Progesterone - Oral Vs. Suppositories

Re: Progesterone - Oral Vs. Suppositories

• jr63_2020 member

  May 2011

  I've heard that the vaginal suppositories are "better", but I knew from previous BFN cycles that my body had trouble absorbing them. I took oral promethium and it seemed to work really well for me. My progesterone was a 45.5 last time they measured it while I was still taking it.

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• julesjb member

  May 2011

  I was on Crinone which I was told was the best for local absorption. It isn't as mess as the other stuff but sorta accumulates in a not so pleasant manner. That being said I was on it from 3 dpo to just this past Saturday at 11 weeks and overall it went fine!! It doesn't change your blood levels much I heard but mine were not vein monitored. I have never had a progesterone issue it's just a mainstay for my RE to start her patients on!! GL I don't think you can go wrong!!

  BFP #1 6/18/10 Saw HB 7/15/10 Missed M/C 8/17/10 @ 12 weeks 2 days- 2 D&C's( 8/20 and 8/26) BFP#2 11/21/10 Nonviable at 5wks, possible ectopic. Methotrexate 12/3/10&12/9/10 BFP#3 3/10/11 Beta@12dpo 39 Beta@14dpo 160! 21 DPO 2439 HB at 7wks 127 EDD 11/17/11
  ITS A BOY!!!! Born 11/13/11 BFP #4: 10/29/12 edd 7/11/12
  

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• romigu member

  May 2011

  My understanding is that the progesterone supplements are better absorbed and reach their therapeutic level more effectively.  In my personal experience, the oral supplements raised my level adequately so my doc kept me on those. 
  

  
  
  

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• luckymrs718

  May 2011

  I'm on oral Prometrium right now and it does the trick.  We were given the option this time around with either sticking with the oral or using a cream, and personally a pill is just so much easier for me.

  BFP #1 - 5/15/10, EDD 2/11/11, missed m/c no heartbeat at u/s, D&C 7/14/10 BFP #2 - 3/14/11, EDD 11/25/11, natural m/c at 5 wks BFP #3 - 4/27/11, DD born 12/14/11

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• lotus88 member

  May 2011

  My MD said the vaginal was a little better because it went directly to where we wanted it. Also she said the oral had to go through the liver. She gave me the option, but leaned toward the vaginal. It's a little messy, but not bad. I just wear a long pantiliner. I haven't had any irritation or infections (though I think it might be why sex was uncomfortable).

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• ColleenS629 member

  May 2011

  My RE had me take Endometrin (vaginal suppository). The other option was PIO, oral wasn't an option. I did IVF though so I wasn't making any progesterone on my own.

  m/c 7/17/10
  Dx: MFI- 3% morph
  IUIs: Gonal-F + Ovidrel + b2b IUI= BFNs
  IVF with ICSI= BFP! EDD 11/25/11
  3/18- Beta #1 452! 3/20- Beta #2 1,026!! 3/27- First u/s- TWINS!
  Our twin boys arrived at 36w5d due to IUGR and a growth discordance

  
  

  FET: Medicated FET moved up to 5/23 due to ovulation

  Transferred a 6BB hatched blastocyst- genetically normal female embryo

  BFP! 5/28- 5dp6dt      

  6/1 Beta #1- 223! 6/3 Beta #2- 567!
  

  
  
  
  Be kinder than necessary, for everyone you meet is fighting some kind of battle.

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• eminbmore member

  May 2011

  The suppositories are more effective, and seem to have fewer side effects.
  

  
  
  
  

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• thewayiam

  May 2011

  Thanks, everyone. As it turns out, they're giving me suppositories whether I want that or not. Sounds like it's a good call though. Thank you for your input.

  
  
  BFP#1 - 8/27/10 - D&C 10/27/10 @ 13 weeks to Trisomy 18
  Missing our Angel Baby Gabriel
  BFP#2 - 3/18/11 - CP 3/19/11 BFP#3 - 4/27/11 - Due 1/9/12

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• TeacherVicky member

  May 2011

  I took prometrium intravaginally. I was glad as I heard the SE were worse when taken orally.

  

  
  

  
  

  
  

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