Tell me about Intralipids

Re: Tell me about Intralipids

• STL34 member

  April 2011

  Intralipids are usually used in addition to a steriod such as dexamethasone and are supposed to help regulate your immune system in some way (not sure about the exact mechanism).  It is an ifusion of certain types of fats.  Other than making my arm extemely cold when it is infused (and the normal bruising I get with IVs), I haven't had any side effects from it.  The first infusion is usually 7-10 days before ET.  With a second infusion after a positive beta.

  I have been on Lovenox, BA, dexamethasone and intralipids for both of my IVF cycles.  I just set up a telephone conference for next Wednesday to discuss these with a reproductive immunologist.  From my correspondence with him, he thinks I should have testing to make sure that they, along with the Humira I am on for my arthritis, are doing what they are supposed to and are not lowering my immune system too much.  So, we will see how that goes.  I may know a little more after that.

  
  
  
  ~SAIF/PAIF/Everyone Welcome~ 
  
  

  Me= 37 and DH = 41 
  
  Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)
  
  IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN
  
  IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.
  
  IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!
  

  TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

  IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

  IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

  IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN
  

  FET#1:  BFN

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• theworms member

  April 2011

  immune testing

  https://www.reproductiveimmunology.com/diagnostic-testing/
  

  intralipids
  

  https://www.reproductiveimmunology.com/treatments/intralipid-therapy/

   

  Dr. B uses intralipids on patients with immune issues but doesn't rec if you don't have any issues because you can over-suppress the immune system
  

   

  
  Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
  Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)
  
  It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
  MTHFR A1298C & C677T, Immune Issues and Factor II
  

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