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Infertility Veterans
Talk to me about lovenox
Quick history: after failed OE IVF #1, I asked RE to run add'l testing. Found out I have mthfr & was borderline on two clotting tests. Upon retest, clotting issues were normal, so decided not to treat. After c/p with DE IVF, asked for those tests to be run one more time. Previous abnormal tests were normal, but now another clotting issue came back borderline abnormal.
So, for DE IVF #2, I will be on lovenox. Ugh, more shots.
I am a little nervous about being on a blood thinner. What if I am in an accident or something? Is this a ridiculous concern?
Any side effects?
TIA!
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Re: Talk to me about lovenox
My main side effect with lovenox is injection site bruising. It isn't too bad until I start baby aspirin, though. Will you be on baby aspirin, too?
If you are really concerned about being in an accident on blood thinners, you could ask to do heparin injections. However, you have to do two injections a day with heparin. However, it doesn't stay in your system as long (thus the two injections) and they have an antidote for it.
Good luck, hon! I hope lovenox is the las piece of the puzzle for you!
~SAIF/PAIF/Everyone Welcome~
Me= 37 and DH = 41
Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)
IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN
IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.
IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132. Lil is here!
TTC#2: Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.
IVF #4: BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN
IVF #5: MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN
IVF #6: (New RE): Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN
FET#1: BFN
Thanks for the info! I will read up on the differences between heparin & lovenox and ask my RE. I'm not sure if I will be on baby aspirin too. I will ask that too.
I hope it is the missing piece as well!
I did Heparin and I am doing Lovenox now, the change mainly being due to insurance coverage. Frankly, I prefer Lovenox, it seems to sting less and, of course, it's only one injection. I only got 2 bruises in 4 weeks on it, it was far worse for me on Heparin.
Good luck, Holly, I hope this is it for you!
TTC since July 2008
IUI 1,2,3 BFN
IVF #1 C/P, FET 1,2,3 BFN
IVF#2 BFP
it's a girl!!
Callan George and Bennett Charles born and died 11/7/10
FET #1 April 2011= BFN
FET #2 July 2011= no transfer because my lining sucked
FET #3 February 2012= BFP! 1st beta 9dp5dt=314 2nd beta 11dp5dt=977 1st U/S 3/20 Twins- Heart rates of 111 and 138
Living After Losing
I was on heparin. I didn't not think the injections were too bad at all. You use the small lupron needle. Like STL said it is twice a day though and it does leave bruises but they do not hurt. It has a shorter life than lovenox and more studies have been done it because it is an older drug and it is approved for use in babies/children. My RE prefers to it lovenox.
I did have a SCH bleed in my 10th weekend of pregnancy and I was bleeding so much they decided to take me off and it was out of my system very quickly. I do understand your concern about being in an accident, etc. I had the same worries.
Me: PCOS, Blood/Immune Issues DH: Low all 3
Jun.- Sep. 2010 IUI#1-#3 = BFN
Oct. 2010 = IVF #1 = B/G Twins (passed away Feb. 2011)
May 2011 = Myomectomy and trans-abdominal cerclage (TAC)
Sep. 2011 = Surprise BFP = C/P
Feb. 2012 = sFET #1 = BFN
Feb.2012 = Hail Mary IUI #4 = BFN
April/May 2012 = FET #2 w/our last two embies = BFP (Please let this be it!)
Beta #1 8dp5/6dt = 234 Beta #2 10dp5/6dt = 695 Beta #3 12dp5/6dt = 1796 Beta #4 17dp5/6dt = 17,888 U/S #1 May 17, 2012 = Twins
Baby B's heart stop beating at 9 weeks 5 days
Our little miracle baby is a boy.
Baby Boy Owen and Baby Girl Avery were born too early on Feb. 13, 2011 due to a pedunculated fibroid, incompetent cervix and suspected placental abruption.
"What the heart has once owned and had, it shall never lose." - Henry Ward Beecher
SAIF/PAIF Welcome
Lots of love and luck to my PAIF/3T/IF Veteran ladies, especially my dear friend Zookie. Congrats to Papps, Teach84 and Starbuck on their little ones.
I took Lovenox while cycling (1x/day) and during my pg (2x/day). It's not the greatest shot - it stings and bruises - but you'll get good at them. I usually did them in my stomach in really good light to help avoid any little blood vessels. Also, after your shot, resist the urge to apply pressure. Anytime I applied pressure, I ended up with a big ol' bruise.
I always used to tell DH that I was glad we lived in the midwest and not someplace where I'd have to wear a bathing suit. Someone would have surely called the cops if they saw my belly! :-P
ETA: A few dumb things I forgot...
* I probably should have mentioned that I was on Lovenox b/c I'm homozygous for Factor V Leiden.
* I never had any issues with bleeding. Even if I cut myself shaving, I never seemed to bleed too much more than normal. You'd just want to make sure someone was aware that you were on it if you had some type of surgery or something.
* I was scheduled to switch to Heparin at 33-34w (it leaves your system faster) but I ended up with sudden pre-e so my OB took my LOs prior to the switch. If you'd stay on it thru your pg, make sure you ask about that.
Thanks everyone!
This was all very helpful information.
the worst part - it burns like a motherfu*cker and leaves bruises
so my tips
ice area first (do shots at least 2 inches from beely button), inject lovenox very slowly (faster injection ='s more burning), leave area alone
i can't really answer about more bleeding i bled a LOT when i m/c but i also have tendency to bleed combined with my factor 2 (to be fair ai bled a lot when i m/c and wasn't on lovenox). i didn't notice more bleeding w/ acu needles or cuts
lovenox leaves your system in 24 hours wo try to do shots at same time
GL cutie
Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)
It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
MTHFR A1298C & C677T, Immune Issues and Factor II
Holly, not sure if you remember me. I met you at a Chicago GTG back in the day at Quartino. Just wanted to say hi and that I hope this is it for you!
I took Lovenox until I had some issues with bleeding (turned out to be an SCH). I just wanted to reiterate, push the plunger slowly, leave it for a second, then once you pull the needle out, do not touch the area AT ALL!! Touching it only ever meant more stinging, bruising and welts for me. But other than that, it's not too bad.
Good luck!
Yes, I remember you! Thanks for the info. William is adorable!!!