I have a question. My Re has me on ganirelix, luveris and follistim for my IVF protocol (I take them all each day of stimming). Has anybody used this? Do you know what kind of protocol this is?
Here is some info on the most common protocols, but there are many more, let alone lots of variation of these core protocols. It sounds like you're doing some kind of antagonist protocol. For mine, I started Ganirelix (the antagonist) after 5 days of stims, but I've heard of protocols using half-doses from the get go.
i agree with E - sounds like a variation of an antagonist protocol although i'm not familiar with the luveris you are taking. is it like menopur maybe?
S/PAIFW
Tara & Dave - TTC since September 2006
PCOS - dx 1999 (amenorrhea) | freakishly long fallopian tubes
Hypoglycemic | thyroid issues | severely anemic
Multiple Clomid cycles of 50, 100, 150 - absolutely no response
Follistim 50/100 | Follistim 75/125 | Follistim 100/150 IUI - all BFNs
Converted IVF - BFP - m/c | FET - BFN | IVF #2 = BFN
IVF #3
I should clarify, and this is a general, as I don't understand the chemistry behind it...
antagonists, such as Ganirelix or Cetrotide, prevent ovulation in one way.
agonists, such as Lupron, prevent ovulation in another way. MDLF protocols take advantage of Lupron's flare reaction to kick-start FSH production.
estrogen priming is a particularly aggressive protocol, and is complex in it's executtion in that there are many ways to prime, and many stim protocols (not just antagonist) it can be combined with. Some clinics have "their" way of doing EPP, not just as described on this blog. But the definition itself is good.
I am not sure about the names of the protocols but from my understanding here's the scoop...
Ganirelix is to prevent premature ovulation...this is so your ovaries don't pick a dominant follicle as they would normally.
Luveris and Follistim work together to stimulate the follicles to grow.
For IVF they want a lot of follicles to grow and grow at the same rate, because if one or two are much larger than the others, they may get released before the others are done growing and there won't be enough follicles to make the IVF retrieval worthwhile. With your combo, basically they are trying to have a whole bunch of follicles that are about the same size so you can maximize the potential eggs for fertilization.
Hope this helps. I am not an RE or an OB/Gyn doc, but I am an internist and pediatrician and most importantly have just joined the IVF bandwagon.
I am not going to Uconn, but SIRM NY. I started at Uconn with my IUIs though, and they were great. But they don't treat immune issues, which I have, while SIRM does. It take me an hour to get to the SIRM satellite office for monitoring, but oh well....who do you see at uconn?
Re: IVF protocol question
Here is some info on the most common protocols, but there are many more, let alone lots of variation of these core protocols. It sounds like you're doing some kind of antagonist protocol. For mine, I started Ganirelix (the antagonist) after 5 days of stims, but I've heard of protocols using half-doses from the get go.
GL!
Tara & Dave - TTC since September 2006
PCOS - dx 1999 (amenorrhea) | freakishly long fallopian tubes
Hypoglycemic | thyroid issues | severely anemic
Multiple Clomid cycles of 50, 100, 150 - absolutely no response
Follistim 50/100 | Follistim 75/125 | Follistim 100/150 IUI - all BFNs
Converted IVF - BFP - m/c | FET - BFN | IVF #2 = BFN
IVF #3
I should clarify, and this is a general, as I don't understand the chemistry behind it...
antagonists, such as Ganirelix or Cetrotide, prevent ovulation in one way.
agonists, such as Lupron, prevent ovulation in another way. MDLF protocols take advantage of Lupron's flare reaction to kick-start FSH production.
estrogen priming is a particularly aggressive protocol, and is complex in it's executtion in that there are many ways to prime, and many stim protocols (not just antagonist) it can be combined with. Some clinics have "their" way of doing EPP, not just as described on this blog. But the definition itself is good.
I am not sure about the names of the protocols but from my understanding here's the scoop...
Ganirelix is to prevent premature ovulation...this is so your ovaries don't pick a dominant follicle as they would normally.
Luveris and Follistim work together to stimulate the follicles to grow.
For IVF they want a lot of follicles to grow and grow at the same rate, because if one or two are much larger than the others, they may get released before the others are done growing and there won't be enough follicles to make the IVF retrieval worthwhile. With your combo, basically they are trying to have a whole bunch of follicles that are about the same size so you can maximize the potential eggs for fertilization.
Hope this helps. I am not an RE or an OB/Gyn doc, but I am an internist and pediatrician and most importantly have just joined the IVF bandwagon.
Good luck!