Infertility

Lupron - s/e, delays AF, general experience w/it **paifw/saifw**

I'm starting Lupron in just about 3 weeks, would you mind sharing your experience on it?

 Side effects, did it delay AF and if so by how long, and other tips.  Did the shot really hurt?  

Thanks all. 

11/10: IUI #1 =100mg Clomid CD4-8 + pregnyl trigger + IUI = chemical pregnancy
1/11: IUI #2 = 5mg Femara + trigger + IUI = BFN
2/11: IUI #3 = injectibles + trigger + IUI = BFN
IVF #1 April 2011 ER 4/23 w/16 eggs retrieved, 14 mature, 11 fert., 4 blasts to freeze, 5dt of 2 blasts on 4/28, beta #1 5/7 = 243... beta #2 5/9 = 491....beta #3 5/11 = 1113!!
my blog

2011-02-04_11-37-12_452
Pregnancy Ticker

Re: Lupron - s/e, delays AF, general experience w/it **paifw/saifw**

  • I didn't have any s/e from lupron, but I was on a very low dose. I've heard some ladies describe a lupron headache or lupron fog. The shots don't hurt. Occasionally, I'd get a bruise from hitting a vessel, but it's not any more painful that any other bruise. Honestly, of all the shots this was by far the easiest.

    I think AF was about 5 days late for me. I'm not sure if that's b/c of the lupron or the bcps.

    Good luck!
    IVF #3 = Feb 2012
    beta#1 3/21 (14dp3dt)=413, beta#2 3/23 (16dp3dt)=785, u/s 4/11
    EDD 11/25/12
    **SAIFW** Baby Birthday Ticker Ticker
  • Loading the player...
  • Lupron is pretty brutal on me! I get a headache the whole time, and it makes me very forgetful!  It just made me feel.. off.   I always get a "lupron period"  My nurse even puts it on the calendar for me!  The shots aren't painful. For me, they are probabally the easiest one!

    Some people get no s/e from the Lupron.. I hope you are one of them! Good luck!

    Renee- 37 DH - Chad - 39
    2/06 - surprise pregnancy - twins
    3/06 - m/c 1st baby at 6 weeks 
    5/06 -2nd baby had no heartbeat at 14 wks.
    D&E - Bled out. Blood transfusions. Week in ICU - Cheated Death!
    Diagnosis: Blood clotting and bleeding disorder, immune issues, & cervical stenosis
    5/10 - 1st IVF cycle - BFN
    FET - 10/12/10 - BFN
    1/11 - IVF with PGD - BFN
    IVF - May - BFN
    6/11 New RE - fingers crossed!
    9/11 - IVF - 4 transferred
    10/13 - BFP!!
    It's a boy! Clint Michael, Due in June!!!

    image
    Baby Birthday Ticker Ticker





  • I was only on 5 units of lupron a day, and I didn't have any side effects.  The shot didn't hurt.  I actually bled on bcp's, so I only had light spotting on lupron, and it started the Thursday after my Sat start day.

    image
    After 2+ years and multiple treatment cycles,
    including an IVF vacation in Costa Rica/Panama,
    IVF #2 brought us our miracle baby!
    Baby Birthday Ticker Ticker

    Surprise!  Baby Boy is on the way!

    image

     

  • kegkeg member

    I'm only on 10 units of lupron now and I'm not experiencing any side effects (and I've been on for several weeks now for a FET).  When I initially did IVF, I think I had a higher dose for a while (20 units?) and the only side effect I had was some insomnia. 

    In terms of AF, if anything I got it about a day earlier, but I was on BCP and I only started lupron a couple days before AF was due, so I'm not sure if that was related to lupron or not.  

    The shot really doesn't hurt at all.  One thing i figured out the first time around is if you have a spot that really hurts going in, stop and do a different spot.  For me if I did it where it hurt, I was more likely to wind up with a bruise, which makes me think I was hitting some type of superficial blood vessel.  This time I haven't injected where it hurts and I have no bruises yet. :-)  Good luck!

    2004-Started TTC; Nov 2007-Lap with endo removed; Jan 2008-Ectopic (mtx); April 2008-IVF #1 (bfp, twin girls); March 2011-FET (cp); June 2012-IVF #2 (bfp, singleton, EDD 3-19-12)

    ***Twin fraternal girls born at 35w6d in 12/2008***

  • Lupron does put me in a terrible fog. But that fog goes away once I get to stop the Lupron.  And it does delay AF by a day or two.  The shot itself is very easy.

    Good luck!

    Warning No formatter is installed for the format bbhtml
  • STL34STL34 member
    I thought the shots were easy.  They didn't hurt.  It also didn't delay AF (AF came early both times I was on it).  I did have side effects.  I got headaches and a brain fog (it was hard to concentrate).  That being said it effects people differently.  Good luck, hon!

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

  • I had on and off major headaches and kind of foggy brain. I was also pretty emotional on it.  To be honest, I had more side effects of this drug than others. But some women say they have none at all.  The shot doesn't really hurt.  GL!
    Married - 8/2009 Diagnosed right away as sub-fertile. PCOS for me and low motility, morphology for DH. On treatment of glucophage and supplements for PCOS. Completely OOP. 4 IUI's - clomid- all BFN's IVF #1- 13 fertilized, no frozens- BFN IVF #2- ER 2/21, 18 retrieved, 12 fertilized. ET 2/24 - 2 beauties. No frozens. BFN. IUI #5 using leftover meds- BFN Trying new meds for PCOS. SAIF & PAIF and prayers welcome! Entering the world of adoption. Choosing happiness and love and focusing on the blessings we do have instead of the things that we don't.
  • AF was delayed by only a day or two. 

    The shots are super easy... painless for me.

    At 5 units I had no side effects.

    At 10 units, I've had hot flashes and night sweats, and an occasional headache.

    Good luck!

    SAIFW
    TTC since 2008 dx PCOS & MFI
    Clomid/Femara no "O"
    IVF #1 BFN
    FET #1 cancelled for biopsy
    FET #1.2 c/p, July 2012 c/p
    IUI #1 & 1.2 canceled
    IVF #2 ER 12/1, Freeze all due to OHSS
    FET #2.1 cancelled due to DVT risk, FET #2.2 Jan 2013
    my blog
    image
  • the actual shot is painless, very small needle.  i did have lots of burning and raised red welts at injection site.  i iced before shot to prevent this

    lupron gives me headaches and occasional night sweats

    GL & PPV

    image
    Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
    Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)

    It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
    MTHFR A1298C & C677T, Immune Issues and Factor II
  • imagelove2b_mrst:
    I was only on 5 units of lupron a day, and I didn't have any side effects.  The shot didn't hurt.  I actually bled on bcp's, so I only had light spotting on lupron, and it started the Thursday after my Sat start day.

    This was me too...it was one of the drugs i didn't mind.

    I spotted on BCP's, and then my lupron period was really light.

    Warning No formatter is installed for the format bbhtml
  • Eeks.  Thanks for sharing everyone.  Why am I having flashbacks of Clomid as I read the responses?!

    I hope I don't have any major s/e.

    11/10: IUI #1 =100mg Clomid CD4-8 + pregnyl trigger + IUI = chemical pregnancy
    1/11: IUI #2 = 5mg Femara + trigger + IUI = BFN
    2/11: IUI #3 = injectibles + trigger + IUI = BFN
    IVF #1 April 2011 ER 4/23 w/16 eggs retrieved, 14 mature, 11 fert., 4 blasts to freeze, 5dt of 2 blasts on 4/28, beta #1 5/7 = 243... beta #2 5/9 = 491....beta #3 5/11 = 1113!!
    my blog

    2011-02-04_11-37-12_452
    Pregnancy Ticker
This discussion has been closed.
Choose Another Board
Search Boards
"
"