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ICSI v "natural" fertilization (paifw/saifw)

OCW2010OCW2010
in Infertility

If you've done ivf, which have you done?  Once there are embryos, will they even know which ones were fertilized w/ICSI vs not?  And do they elect to transfer in the one(s) that were not ICSI'd?

Just looking to hear your experiences.

Also, if you did this, what was the fertilization rate with natural vs ICSI?

Thanks ladies 

11/10: IUI #1 =100mg Clomid CD4-8 + pregnyl trigger + IUI = chemical pregnancy
1/11: IUI #2 = 5mg Femara + trigger + IUI = BFN
2/11: IUI #3 = injectibles + trigger + IUI = BFN
IVF #1 April 2011 ER 4/23 w/16 eggs retrieved, 14 mature, 11 fert., 4 blasts to freeze, 5dt of 2 blasts on 4/28, beta #1 5/7 = 243... beta #2 5/9 = 491....beta #3 5/11 = 1113!!
my blog

2011-02-04_11-37-12_452
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Re: ICSI v "natural" fertilization (paifw/saifw)

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    STL34STL34 member

    The RE at the clinic with whom I did both of my IVF cycles does ICSI with everyone.  They do a high resolution selection of sperm for ICSI and don't see any benefit to "natural" fertilization. 

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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    OCW2010OCW2010
    imageSTL34:

    The RE at the clinic with whom I did both of my IVF cycles does ICSI with everyone.  They do a high resolution selection of sperm for ICSI and don't see any benefit to "natural" fertilization. 

    Thanks ST.  I'm going to ask my RE/nurse about this and whether they do it too. 

    11/10: IUI #1 =100mg Clomid CD4-8 + pregnyl trigger + IUI = chemical pregnancy
    1/11: IUI #2 = 5mg Femara + trigger + IUI = BFN
    2/11: IUI #3 = injectibles + trigger + IUI = BFN
    IVF #1 April 2011 ER 4/23 w/16 eggs retrieved, 14 mature, 11 fert., 4 blasts to freeze, 5dt of 2 blasts on 4/28, beta #1 5/7 = 243... beta #2 5/9 = 491....beta #3 5/11 = 1113!!
    my blog

    2011-02-04_11-37-12_452
    Pregnancy Ticker
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    chizzle09chizzle09

    MH's motility was a little slow so they split my eggs in half and ICSI's half and the other eggs were "naturally" fertilized. Both fertilized exactly the same amount. The naturally fertilized ones ended up doing a little bit better than the ICSI'd ones, but it was really close. Good luck!

    Edit: They kept track of the 2 groups. I don't know which ones they put back in. I don't think it made a difference, really. I had a 5dt of 2 blasts.

    TTC #1 since 7/09
    Dx: LPD, underdeveloped follicles, blocked left tube
    3 C/P, 1 BO, 1 Ectopic
    IVF#1=BFN (3/11)
    FET#1=BFP
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    Temp935838312504158Temp935838312504158
    imageSTL34:

    The RE at the clinic with whom I did both of my IVF cycles does ICSI with everyone.  They do a high resolution selection of sperm for ICSI and don't see any benefit to "natural" fertilization. 

    This exactly per my RE at my clinic.

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    missjul61missjul61 member

    Although my DH had normal SAs, we did half ICSI and half natural fertilization just in case. They did kerp the two groups separated. Te ICSI group did slightly better than the natural fert group so the two blasts we transferred were ICSI'd.

    ETA: The fertilization rate was the same for both groups. 

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    ellenchris0506ellenchris0506
    My RE recommended that we do ICSI due to my husband's low count. 
    Ellen & Chris 5/6/06
    -------------------------
    TTC Since 10/2007 with no luck and a 'go with the flow' attitude
    1/1010 FINALLY decided to have testing done, dx MFI
    7/2010 - DH starts Clomid to increase testosterone and hopefully sperm count
    10/2010 - Still low (but improved) sperm count.
    11/30/10 - IUI #1 and only = BFN
    February 2011 - IVF #1 w/ ICSI =
    Chemical PG (Beta 1: 10, Beta 2: 19, Beta 3: 17) :-(
    April 2011 - IVF #2 w/ ICSI = BFN :-(
    September 2011 - IVF #3 w/ ICSI = BFFN
    November 2011 - AMH level tested - .83 (normal for age range)
    February 2012 - IVF #4 w/ ICSI = (best response ever yet still) BFFN
    April 2012 - DNA testing - NORMAL, RE suggests cycling again with own eggs or using DE
    On Break indefinitely...not sure we can afford the emotional and financial roller coaster anymore.
    *PAIFW/SAIFW*
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    magnolia_femmemagnolia_femme
    we did ICSI for all three, and our fert rates were pretty good. 
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    eclepticecleptic
    Our clinic does routine ICSI for all cycles. We need it regardless but all the research I've done shows that it significantly increases implantation rates when the sperm sample is less than ideal and does no harm when the sample is good.
    image
    Friends for 15 years. Married 8. TTC since January 2009
    2010 Diagnosis: Anovulation and Severe MFI
    2011 Treatment:
    IVF w/ICSI #1 Antagonist: 2 blasts - c/p - BFN 04.22
    FET #1: 1 blast/1 early blast - BFP 06.22 - m/c 06.30 @6w0d
    07-11 RPL: MTHFR C677T Heterozygous & Slightly elevated ACLA IgM
    FET #2: 1 morula - BFN: 9.02

    January '12: IVF #2
    Started BCP and Metformin (New!) 12-14 for stimming in January

    Dum spiro, spero.
    ?SAIF/PAIF/PgAL/PAL always welcome?
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    ej708ej708 member

    We did all ICSI, but we were also dealing with MFI.  Out of 6 mature eggs, 5 fertilized and 4 made it to blast (transferred 2 and froze 1).

    Good luck!

    Our IVF miracles arrived on 7/20/11 at 37 weeks after 3 weeks of hospital bedrest! Lilypie Second Birthday tickers "Stubbornly persist, and you will find that the limits of your stubbornness go well beyond the stubbornness of your limits." ~Robert Brault
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    sb78sb78
    We did ICSI due to MFI (low count), but I believe my RE ICSI's everyone who does IVF.
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    illinigalillinigal member

    Due to our MFI diagnosis, they ICSI'd 100% of my eggs. 

    IVF #1- 11 retrieved, 9 mature and ICSI'd, 7 fertilized

    IVF #2.2- 14 retrieved, 11 mature and ICSI'd, but only 6 fertilized.

     

    TTC #1 since October 2008. Dealing with MFI.
    IVF #1 w ICSI in July 2010 = BFN
    IVF #2.1 in Oct 2010 converted to IUI = BFN
    IVF #2.2 w ICSI in Dec 2010 = BFN
    Met with new RE in new city on 1/31/11.
    IVF #3 w ICSI in April 2011. HPT on 5/9 = BFP!
    Beta #1 on 5/10 (10dp5dt) = 99.4. Beta #2 on 5/12 = 284. First u/s on 5/26. = Fraternal TWINS!
    Twin boys born & lost on 8/16/11 at 18w1d due to PPROM & preterm labor.
    IVF #4.1 in Jan 2012 converted to IUI on 1/7/12 = BFN
    IVF #4.2 w ICSI in Feb 2012. Lupron on 2/10. Stims on 2/18. ER on 2/29- 7R,6F
    ET scheduled for 3/5/12- nothing to transfer :(
    Dh seeing new MFI uro & Dh starting meds- June 2012.
    IVF #5 in Dec 2012 = BFFN.
    IVF #6 planned for Spring 2013. Praying for our take home baby/ies.
    **P/SAIF and P/SAL always welcome!**

    Lilypie Angel and Memorial tickers
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    kegkeg member
    Our clinic only does ICSI if there are MFI issues.  Since we didn't have any (only dx is endo), we did natural.  They retrieved 16 and only 4 fertilized.  However, I think that a bunch of the 16 weren't mature (they only check maturity for ICSI).  We did a 3dt of 2 and have frat twins and the other two are frozen (planning for a FET this week). 
    2004-Started TTC; Nov 2007-Lap with endo removed; Jan 2008-Ectopic (mtx); April 2008-IVF #1 (bfp, twin girls); March 2011-FET (cp); June 2012-IVF #2 (bfp, singleton, EDD 3-19-12)

    ***Twin fraternal girls born at 35w6d in 12/2008***

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