Anyone have success with IUI after 3 failed tries?

babymomma78 · March 2011

Good morning ladies;

I used to be a regular on TTCAL, but I'm not really a regular anywhere anymore - more of a lurker.

I've had 3 failed IUI's - but the first one should have been cx'ed (clomid resulted in 5-6 mature follies with 5mm lining on trigger day). The second 2 IUI's have been femara/trigger with 2 mature follies and 9mm+ lining on the day of trigger. We are unexplained and my husbands' swimmers are good.

A few posts I made on IF made me think I should seek out a new RE, and so I had a consult with one yesterday. She pushed IVF like I couldn't believe and made me think it was my only hope - even though we are OOP for a few more months. She said, "3 IUIs, even though the first should have been cancelled, is enough to convince me that IUIs don't work for you. You can try a few more and maybe get lucky, but you're probably wasting your time and money."

My existing RE wants to do one more femara/trigger cycle before moving onto 3 injectible IUI cycles. Then IVF.

So after all this - I'm wondering if anyone has had success with IUI after 3 failed tries? Or did anyone move right on to IVF after 3 failed IUIs?

Thanks for reading, and for any feedback!

ColleenS629 · March 2011

I'm surprised that the new RE wouldn't try injects/ IUI first before talking about IVF.

Brownee79 · March 2011

I did!!! I had 5 failed cycles on clomid. Only two cycles produced 1 mature follicle. So I had two failed IUI's on clomid. Then I was switched to Follistim. I had one failed IUI on that with 1 follicle. Second cycle of Follistim I had three mature follicles and my fourth IUI. I am almost 7 weeks now. I go for u/s tomorrow! I just hope everything is ok!!! Good luck!!!!!!!!!!

MSaksa · March 2011

We got PG on our 5th IUI, second one on injects. We did so many because we were going to be OOP for IVF. GL!

aj5oh00 · March 2011

I moved to IVF after 4 failed IUI's...all 4 were with Femara and trigger and I had 2-3 follies and a great (11+) lining every time. We were dealing with both my PCOS and DH's low motility/count so it made sense for us to move to IVF.

orange682 · March 2011

I had 3 failed IUI's (clomid and trigger) when we moved onto injections. I got pregnant with twins that 4th cycle.

kelfeen · March 2011

MSaksa:
We got PG on our 5th IUI, second one on injects. We did so many because we were going to be OOP for IVF. GL!

This exactly. I actually had a BFP with #4 (first with follistim) but it was a c/p.

I did #5 with back to back iui's immediately after that cycle and I am currently 7.5 weeks!

Temp616379875002458 · March 2011

I did not. We did IUIs with clomid then moved on to IUIs with injectables. None of that worked BUT doing a couple of injectable cycles before IVF did accurately show my RE how I responded to the meds (at a much lower and cheaper dose). I think it helped provide good research for the IVF and a more successful outcome...

June0609 · March 2011

I moved to IVF after 3 clomid + TI and 3 IUIs with injectables. I'm OOP for everyting and just did not want to waste any more time/money with IUIs. I'm convinced that more clomid cycles or more injectable cycles wouldn't work for us because each cycle we did I always have 2 or 3 good follies and my DH produced good quality samples and it just never worked.

For us 3 IUIs with injectables cost almost the same as 1 IVF. I'm glad we moved on because we got our first ever BFP with the first IVF.

Goldengirl16 · March 2011

Hmmm, that seems to be jumping the gun a little bit. To give you a little background, there's nothing wrong with me, but DH has azoo. We tried 4 DIUI's with DD and it worked on the 4th cycle. We were doing clomid, trigger and progesterone supps. I'd definitely try a few more IUI's before moving to IVF. Good luck and keep us posted!

Sarafuss · March 2011

We conceived on our third Femara IUI cycle. We had done 3 clomid TI cycles prior to that (2 were with my OB). My RE said that he does one protocol for 3-4 cycles before switching to another. We would have switched to injectables + IUI if our last IUI hadn't worked. We were completely OOP and IVF wasn't an option for us financially. Good luck with your decision!

kelfeen · March 2011

PappsMcgee:
ColleenS629:
I'm surprised that the new RE wouldn't try injects/ IUI first before talking about IVF.

This is what I was thinking! I got pregnant on our 4th IUI.... we switched to injects. Can you ask and see if they'll try that? If not, I might get a second opinion

There are a handful of ladies on my local IF board whose RE did this as well. I thought it was strange too. Though if I had IF coverage I might have jumped to IVF too - the odds are so much higher and I just wanted all the madness to come to an end.

autumnlala · March 2011

We moved on to IVF after two failed IUIs with donor sperm. Both failed IUI cycles looked perfect, but didn't work. Honestly, I just couldn't take the emotional roller coaster and devastation of failure, and was ready to take my chances with something more likely to actually work. We were looking at a 10-20% success rate for each IUI, but because I'm young and healthy with no known fertility issues (31yo), we'd probably 60% success rate with IVF.

My RE thinks I may have endometriosis, which would make the IUIs less likely to work but does not interfere with IVF. Who knows. I did get a second opinion after the two failures, and the doc basically said we could try one or two more IUIs (I'm a good responder so injectibles wouldn't have been a good idea, would have ended up with too many eggs), and they might work, but they might not. It was just how much we could take emotionally and what we were willing to do financially.

I got a BFP after our first IVF, and we have 7 high quality frozen embryos for future tries if this one doesn't stick, or siblings!

msjcordova · March 2011

1st IUI cycle- 50 mg of clomid+metformin+hcg= bfn

2nd IUI cycle- 100 mg clomid= Cancelled due to no responce

3rd IUI cycle- 150 mg clomid +metformin+hcg+ prog. supps= bfn

4th IUI cycle- 5mg Femara+metformin+hcg+ prog supps= bfp

amamommy · March 2011

For this pregnancy we conceieved on our 4th IUI. (injectables +trigger, clomid did not work for us)

halfnhalf · March 2011

MSaksa:
We got PG on our 5th IUI, second one on injects. We did so many because we were going to be OOP for IVF. GL!

Same here. Except it was our 3rd time doing injects (one of which we did not do an IUI). I personally wanted to exhaust ALL our possibilities before spending the $ on IVF, and I'm glad I did. GL to you!

ginogomermisser · March 2011

I had success after my second with Clomid.Good luck

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