Trouble TTC

Clomid, Estradiol, and Prometrium

Quick question ladies...My first month on meds (October) my doctor prescribed 50mg of Clomid days 5-9...and it worked like magic, BFP for me.  Unfortunately I miscarried.  Now in January my first month TTC post m/c, the doctor still had me on 50 mg Clomid days 5-9, this time horrible headaches and symptoms of overstimulated ovaries. :-(  However, with CD1 today the doctor has increased my Clomid to 100mg days 3-7, 2mg Estradiol days 8-12, and Prometrium days 17-28 (or end of 1st trimester).  I have done some reading on Estradiol and it appears there are a LOT of really bad side effects...Have any of you taken Estradiol?  What experiences or s/e did you have?  Anyone taken this combination of meds?  What were your experiences or s/e?  If it makes a difference, I have PCOS...TIA
BFP #1 4/07, 6/07 MMC 9w6d D&C | DX PCOS/annovulatory | BFP #2 (50 mg Clomid) 11/8/10, Natural MC 11/25/10 | Cycle #1 (50 mg Clomid) BFN | Cycle #2 (100 mg Clomid) BFN | Cycle #3 (100 mg Clomid & HCG trigger) BFN | Cycle #4 (100 mg Clomid, HCG trigger, & IUI)= BFN | Cycle #5 (150 mg Clomid, HCG trigger, & IUI) = BFP --> Beta #1 12DPO: 48, Beta #2 14dpo: 171, Progesterone: 105, Beta #3 19dpo: 2,418 BabyFruit Ticker BabyFetus Ticker

Re: Clomid, Estradiol, and Prometrium

  • I take estradiol days 10-12 and it just makes me a little weepy.
    Started TTC May 2010 Dx PCOS Nov 2010 DH dx with abnormal morph, low motility, poor progression, March 2011 Nov 2010, Femara, 2.5 mg + TI, = no response Dec 2010, Femara 5 mg + TI, 1 mature follie = BFN Jan 2011, Femara 5 mg + TI = no response Feb 2011, Femara 7.5 mg + TI, 2 mature follies = BFN March 2011-break April 2011, Clomid, 100 mg = no response May 2011, Femara 7.5 mg + Bravelle = no response, ovarian cyst Jun 2011, Checked for cysts, 1 unexpected mature follie, trigger shot + TI = BFN Jul 2011, Femara 10 mg + IUI #1, 2 mature follies = BFN Aug 2011, break
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  • I am a lurker from TTGP.  I took Clomid (100) days 3-7, 6mg Estradiol days 8-12 and Crinone gel at 3dpo.  I didn't notice a lot of s/e from the Estradiol- a lot less from that than Clomid.  However, my progesterone was still too low. 

    I hope it goes easy on you!

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  • I am taking estradiol. It makes me really nausious (sp?). The first night I vomited all night (TMI-sorry). I am taking 3 pills a day and that day I took 2 at once. After that I have been taking them with a shot of pepto to  coat my stomach and def. only one at a time and that seems to help. I do not think that is the norm though, I seem to react badly to all of these meds. I also was on 150mg clomid right before then.
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