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***STL34***

Jeannie1220Jeannie1220
in Trouble TTC
Thanks for the thoughts.  Quick question for you...I saw in your siggy that you used intralipids. Does that mean you have the natural killer cells? I was going to try that at my Embryo transfer (intraplipids) to help with implantation, but with not so good news, I don't know if transfer will happen.  TIA.
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Re: ***STL34***

  • STL34STL34 member

    It is a bit of a story.  My RE wanted to test me for Nka (activated natural killer cells).  However, I take Humira for ankylosing spondylitis and Humira could cause a false negative on the Nka test (some REs treat Nka+ with Humira).  I was asked to stop taking the Humira before IVF #1, but not soon enough to test for Nka, so my RE wanted me to do the intralipids anyway.  According to my clinic, I am a prime candidate for immune problems because (i) I have an autoimmune disease, (ii) I have endo, (iii) I tested positive for a bunch of the APAs, (iv) I have had positive ANA tests, and (v) my TSH has always been near the top of the normal range (my clinic usually tests for anti-thyroid antibodies in these situations, but they didn't test this for me). 

    I took my Humira during IVF #2, but we still did IL.

    For my, I figured if it is completely safe, can't hurt anything and might help, why not go for it.  Additionally, where I live the Nka testing costs significantly more than the infusions.

    I hope you get some good news on Saturday and get to go to transfer.  ((HUGS))  Sending positive growing vibes to your embies.

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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  • Jeannie1220Jeannie1220
    Wow that is quite a story. :) Thanks for sharing and the good vibes. I was surprised that when I went to pick up the intralipids it was covered under my insurance. I guess it's used not only for IVF.
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  • STL34STL34 member

    Intralipids are actually used as a source of calories in some situations (nutritional supplement) and was approved by the FDA for that purpose a long time ago (it seems like maybe in the 70s).  I couldn't get inurance coverage for it, though.

    Sorry it was such a long story.  It boils down to I wasn't tested for natural killer activation, but I was presumed to have it by my RE and thus given IL.

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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