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If clomid doesn't work out

Persephone0024Persephone0024
in Trouble TTC
I have done 5 rounds or clomid within the last year, three with no response or O at all and two where I O'd but BFN. Is it time to move on from Clomd? And what would be the next step? My RE has mapped out another clomid cycle this month but I would like some suggestions! On a side note, the last two times I took clomid I had some wierd visual things happen at night like light flashes and" trailing" with movement (kinda hard to explain) so maybe that's a sign that I shouldn't take clomid?
Baby Birthday Ticker TickerBabyFruit Ticker TTC since 1/10 DX PCOS Early 2010: 3 rounds of Clomid 50mg, 100mg, & 150mg. responded to first cycle, but all BFN summer 2010: break 10/10: 100 mg Clomid cancelled due to no response 11/10: RE consult: begin Metformin 1500 mg + I month BCPs 12/10: 100 mg Clomid + Hcg + TI + progesterone = BFN 1/11: 5 mg Femera + Hcg + IUI + progesterone = BFP!!! 2/21/11: beta # 1 116 2/23: beta # 2 57 =2/25 m/c 3/2011: break cycle 3/30/11: surprise BFP! beta #1 =36 beta #2 4/1/11= 87 beta #3 4/5/11= 701 4/20/11: US hb found @ 6w2d
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Re: If clomid doesn't work out

  • peppersnicpeppersnic

    If out of 5 times you only responded twice then yes it is time to move on.  I think most ladies that don't respond to Clomid move on the injectables.  Im not totally sure on that and I am sure some of these ladies can correct me. 

    I have done 2 rounds of Clomid and did respond nicely to both, but for my 3rd we will be moving on the Femera or Injectables depending on MH's SA 2morrow.  If he has an excellent SA then we will go on to Femera next cycle but if not on to injectables so I will produce more follies and have a better chance.  I think some ladies even do half Femera and half injectables so there is also something to talk to your RE about.

     I hope you can move on to something that you will respond better to.

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  • Persephone0024Persephone0024
    I was thinking injectables too. It is frustrating to think about moving on to another round of clomid that I'm certain will be a failure again!
    Baby Birthday Ticker TickerBabyFruit Ticker TTC since 1/10 DX PCOS Early 2010: 3 rounds of Clomid 50mg, 100mg, & 150mg. responded to first cycle, but all BFN summer 2010: break 10/10: 100 mg Clomid cancelled due to no response 11/10: RE consult: begin Metformin 1500 mg + I month BCPs 12/10: 100 mg Clomid + Hcg + TI + progesterone = BFN 1/11: 5 mg Femera + Hcg + IUI + progesterone = BFP!!! 2/21/11: beta # 1 116 2/23: beta # 2 57 =2/25 m/c 3/2011: break cycle 3/30/11: surprise BFP! beta #1 =36 beta #2 4/1/11= 87 beta #3 4/5/11= 701 4/20/11: US hb found @ 6w2d
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  • apaige25apaige25
    I would move on to injects if I were you.  Are you seeing an RE?  Most RE's wouldn't have kept you on clomid so long if you weren't responding well.
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  • apaige25apaige25
    Oh, nevermind.  Just reread that you are seeing an RE.  Long day.
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  • Persephone0024Persephone0024
    yes, saw an RE in november, but previous cycles were by an OB/GYN and not monitored, plus I was not on metformin then
    Baby Birthday Ticker TickerBabyFruit Ticker TTC since 1/10 DX PCOS Early 2010: 3 rounds of Clomid 50mg, 100mg, & 150mg. responded to first cycle, but all BFN summer 2010: break 10/10: 100 mg Clomid cancelled due to no response 11/10: RE consult: begin Metformin 1500 mg + I month BCPs 12/10: 100 mg Clomid + Hcg + TI + progesterone = BFN 1/11: 5 mg Femera + Hcg + IUI + progesterone = BFP!!! 2/21/11: beta # 1 116 2/23: beta # 2 57 =2/25 m/c 3/2011: break cycle 3/30/11: surprise BFP! beta #1 =36 beta #2 4/1/11= 87 beta #3 4/5/11= 701 4/20/11: US hb found @ 6w2d
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  • missjul61missjul61 member
    I would move onto injectables. If this round of clomid doesn't work out for me (7th, but 3 with IUI), I'm definitely moving on to injectables.  Good luck to you!
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  • abvernonabvernon
    I would move on to injectables. I did 3 rounds of Clomid with minimal response and one round of Femara with horrible response. Injectables will be me for next month
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  • Aime32Aime32 member
    I think it is time for you to talk to your RE about moving onto injectables.  My RE gave me a 5 cycle limit for clomid and then move to other treatment.  I just had my lap/hysteroscopy done to see if there were underlying isses and I will now move on to injectables.  I had fairly good response with clomid but something wasn't clicking.  GL to you
    Life As I Know It
    TTC #1 Since 2/2008
    Dx: Hyperprolactinemia and Unexplained
    Parlodel 2.5 mg (1 Tab M,W,F; 1/2 tab the other days); Folic Acid; Prenatals
    All 5 Clomid cylces resulted in BFN; no more Clomid.
    Laparoscopy Scheduled 1/11/11: Path report showed minor inflammation and infection.
    3/30/11 Biopsy results: cervial and endometrial pathologies normal; one pathology came back abnormal with 5 rare cells from the endometritis
    Cycles 1-5 of Follistim, Novarel, Progesterone = BFN
    Surprise BFP 11/18/11
    Beta #1 208, p4 7.4; Beta #2 1846.20, p4 16.1
    u/s #1 12/2/11 Heart rate 126 bpm measuring at 3mm
    Baby Birthday Ticker Ticker
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