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Pity Party for One..

Mrs.McIrishMrs.McIrish member
in TTC after 35

I've told this board before that I am BRCA1+ which means I have the breast cancer/ovarian gene.  Protocol is to remove my ovaries around 40 (I am 37).  For some reason today I wondered if fertility drugs would be riskier for me due to the BRCA gene. I wasn't as concerned about the ovaries since I will be removing them anyway but was wondering if drugs would raise my already-high risk for breast cancer. So, I took to googling my theory.  What I discovered instead is that there is a link to BRCA1+ and infertility!  Apparently the studies say the BRCA1 mutuation may lead to early dimishment of egg reserve and that there is a low response to fertility drugs being successful. I really enjoyed the advice they gave: to have a family early!! Gee, thanks.. let me get in my time machine to go back a decade.  I'm freaking out a bit since I took the First Response fertility test a few weeks ago and it said my ovarian reserve was crappy.  I know I am jumping ahead but it all seems to fit together (in a bad way). I guess my appt with the RE next month will be interesting.  I guess I just wanted to vent. Thanks for reading.

TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

K & K born 11/21/14 at 38wks 4 days

imageimage

SAIF/PAIF Welcome


http://waitingforraintostop.wordpress.com

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Re: Pity Party for One..

  • shyntrueshyntrue
    ((Hugs))
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  • aurora1974aurora1974 member
    Oh Mrs., I'm so sorry.  Sometimes the internet is way more of a problem than it is a help.  I know it's easy for me to say, but try not to worry about it too much at this point.  There may be things your RE knows about that you're not going to find on the google search.   And when you go in next month, just make sure that you tell them your concerns about this and I'm sure they'll help you through.  You're in my t&p's. 
    image
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  • lhcooperlhcooper member
    I'm with aurora1974; sometimes a little knowledge, brought oh-so-helpfully to us by the powers of Google, can be a dangerous or at least depressing thing.  Not that it's not good to have informed yourself, because you're now that much more prepared to talk with the RE.  But (and I say this as someone who can't stop Googling when I'm on the hunt for medical info of all kinds), try to now put it out of your mind and assume that your RE is going to help you put together a workable plan for your situation.  A drink might help if you're in that part of your cycle when you feel you can have one.  Wink
    me - 41 (dx: DOR); DH - 53 (no problems); 7/18/09 - married!; 8/4/09 - BFP on first (real)try; 9/14/09 - missed m/c; 9/15/09 - d&c; 11/09 - 3/10 - 4 natural cycles = BFN; 4/10 - dx hyperthyroidism caused by Graves' disease; 6/10 - thyroidectomy; 7/10 - 12/10 - 1 natural and 5 medicated IUI cycles = BFN; 1/11 - new RE; dx low ovarian reserve (AMH .42; 1/26/11 -- BFP (ectopic) from IUI #6; methotrexate 2/10/11; 6/2/11 - IVF #1 = BFN; 9/12/11 - prescreening for DE; 9/15/11 - IUI #7 (unmedicated)= BFN; 11/8 - begin DE cycle (shared risk program); 12/5 - ER (5 eggs/4 mature/3 fertilized/2 left by day 5) 12/10 - ET of one 1BB blast (expanded, "fair" quality), none to freeze; 12/22 - totally shocked by +hpt; beta #1 = 413; #2 = 3952 2/14 - CVS reveals a healthy baby girl! EDD: 8/27/12 DD born 8/31/12, 10 lbs 10 oz and perfect in every way. 
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  • Mrs.McIrishMrs.McIrish member
    Yes, I need to step away from Google!  Thanks for your support ladies. I'm coming to the bar in a minute:-)

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

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  • karenannmarkkarenannmark
    I dont have much advice sorry hun, id say the majority of us 'older gals' here are the same, my FSH test were high which indicates DOR also, we only need one good egg, my sis in law was told she was going through early menopause and she got pregnant (she wasnt trying as she didnt think she would be able to get pg) she has 3 already and this was no.4, a surprise, a beautiful girl, she is now 2yrs, there is always hope, we cant give up, i hope you feel better soon (((hugs)))
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  • boymamacoboymamaco member

    imageMrs.McIrish:
    Yes, I need to step away from Google!  Thanks for your support ladies. I'm coming to the bar in a minute:-)

    I've been doing the same thing and getting myself all worked up in a tizzy! Hang in there. I'm happy to hear your appointment is next month! Not too long to wait. Hugs!

    image

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