Infertility

poor responder to meds

Hi All,

 I had my IVF cycle cancelled two weeks ago due to being a poor responder to the meds. I had itty bitty follicles and not one became full size. I was on Lupron, Menopur and Follistim. My DH and I meet with our RE on Tuesday to discuss the next step. I've heard of other protocols used on those who are poor responders. Is anyone out there a poor responder to IVF meds and has a used a med protocol that worked? Any info would be greatly appreciated!!

Re: poor responder to meds

  • I am DOR, so a poor responder.  I have had better results with EPP (Estrogen Priming Protocol), but I think it is for AMA (Advanced Maternal Age).

    What protocol where you on?  What was your AFC (Antral Follicle Count on CD3)? 

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  • I have had 2 cycles cancelled.  One was a long lupron (which I responded to previously) and the other was the antagonist.  I am currently trying microdose lupron this cycle, which is supposed to help poor responders. 

    My RE put me on BCP for only 15 days, so I dodn't over-supress and I will be on 450IU Gonal-f and 225 IU Menopur.  Those are my highest doses (by far) to date. 

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  • Poor responder in the house and a LATE responder that at.  I almost got cancelled it was a VERY VERY close call and one heck of a roller coaster!  My protocol was micro-flare (I think) 

     

    • Lurpon 20 units AM/PM
    • Stims started 2 days later
    • Menopur 4 powders (AM)
    • Gonal F 300 Units (PM)

    HOpe it helps!  It did work in the end and I only had 10 antral follicles and not all of them responded.  Good luck to you, please don't lose hope I know it is an absolute downer.

    Married to the Mr. 8/6/2008- Together 10+ TTC #2 R/X unexplained infertility/premature ovarian failure/diminished ovarian reserve
    FSH (16) AMH (.61) AFC (9)
    Male factor: low sperm count/ low motility
    IVF #1 11/10 brought us DS Stimming for IVF #2 begin 11/5/11 AFC (7) =( Protocol: Lurpon flare (2 days) + Lupron 10ml/Menopur 4 vials (AM) Lupron 10ml/300IU Gonal-F PM (converted to IUI) failed IVF 2.1 1/12 BFP!
  • I responded poorly to Lupron. Then with an antagonist cycle I got more eggs, but all of them piss poor quality. We did an estrogen priming protocol and I got both good numbers and great quality. It resulted in my son. 
    A lot of years and a million tears finally led me to you.
    After 7 years trying to concieve, 3 failed IUIs and 2 failed IVFs, my third IVF was a success!
    My Christmas baby turned into a turkey bird! Dillon Richard was born at 34 weeks, 5 days on November 28, 2009 after 10 weeks on bedrest for preeclampsia.
    <a href="http://smg.photobucket.com/albums/v705/arriinthere/PJ/?action=view
  • hi! thanks for your response. when my cycle was cancelled, my re mentioned taking me off of lupron but nothing about epp.

    i was on bcp, 10 units of lupron then reducing to 5, two vials of 75 units of menopur and 300 of follistim.

     

    my afc was 6 but none of them grew to full size.

     

     

  • thanks, everyone! i never thought trying to get pregnant would be so hard and thought ivf would be the easy fix!
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