Good news! We had our genetic counseling today and they confirmed what I was hoping to here. We are NOT carriers of balanced chromosomal translocation! Our fetal tissues had a translocation as well as some extra chromosomal material, but it is believed to be a random occurrence. The results of our individual genetic tests that looked at all 23 of our chromosomes individually (from the test we thankfully already took back in February) show that we are both normal. The good news here is that we can continue to try naturally and there is no hurry to try the painful and expensive approach of IVF plus PGD as we were considering. The next steps are trying to get pregnant again naturally and relying on prenatal genetic testing (2 tests- amniocentesis and CVS)
The only bad news is that we continue to have unexplained recurrent pregnancy loss with no new steps to change the outcome for the next round. The only changes I am making right now is trying weekly acupuncture trying to improve my overall health through diet and exercise. I've been twice so far and I actually do feel something happening to my body while the needles are there. The specialist I see also wants me to take chinese herbs, but) my RE doesn't want me to take any herbs at the same time because she is concerned about the affects of the combination with the fertility drugs (Femara and Progesterone). For helping with the emotional side my RE approved my request for anti-depressants. I will see my primary care physician tomorrow to ask her for the actual prescription. Of course I also have my blog community (thank you readers!), message boards, face-to-face support groups (via Resolve and at Stanford), individual counseling as well as (and a loving husband) for emotional support. Next week there is even a seminar on the topic just up the road at Stanford. It will be good to hear opinions from other medical experts on the subject. In case you are interested, here is a nice link to information on recurrent pregnancy loss.
Re: Moving forward after loss #3, Could they all be due to random chromosomal issues?
I'm sorry for your losses!
I'm in the same boat as you--3 losses and tests came back normal. I'm not even getting pregnant anymore with the fertility meds I'm taking. Next cycle we're going to try naturally again, and if we miscarry, we'll know for sure it's not just bad luck. My RE recommends IVF with PGD for me, because he says it could still be random chromosomal issues.
I don't see the link!
sorry for your losses but glad your chromosomes are ok! that's good news.
I'm interested in how the accupuncture goes. i may look into doing this myself.
Doctors have relied for a number of years on old, bad studies regarding loss and the likelihood of subsequent losses. Turns out the most recent research shows that 1, 2, or 3 losses, your risk doesn't really increase until you're over 5-7 losses. Of course after your 3rd loss, statistics don't mean much - I get that.
But they could be. They could all be due to some randomness. They could be due to something we don't understand. I just don't know. I had a thin thread o fhope after loss #3, but by God, I planned on holding on to it, you know?
I'm sorry. Moving forward is hard after a single loss - and it seems to compound with subsequent losses. I just kept telling myself - we've done this. We've been through those hard scary times. We can do it again if we have to - because the reward is great if it works, you know?
I'm sorry. I wanted this to sound much more "Rah rah you can do it" but words fail me. Often. When discussing multiple losses, that is.
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