progesterone suppositories vs PIO

Sarah&royale · October 2010

What is the difference? They are both progesterone?

Sarah&royale · October 2010

i know the pio is a shot, but I'm just curious why the drs choose one over the other?

njohnson1972 · October 2010

Yes.

PIO goes IM - big needle, ugly shot, bruised rear end.

Progesterone Suppository - easier application, messy.

Big difference - Progesterone levels can be measured through bloodwork with PIO. You can't get an accurate measure with the suppositories.

Having done both, I tend to prefer PIO because my RE can measure my progesterone levels and I am that obsessive.

Faith722 · October 2010

My nurse said that studies show the injections and suppositories are equally effective. They do PIO from ER to ET, then suppositories after that.

Sarah&royale · October 2010

ah, okay. good to know. I have a bunch of the suppositories and recall my dr talking about the PIO so that's why I was wondering. Thanks for the heads up! I didn't know about the bw part.

AnieS · October 2010

My doc gives the option. I chose the PIO shots bc the suppositories were 3x/day vs 1x/day for the shot. The fewer meds I have to worry about, the better.

Yellow_Daisy · October 2010

My doc prescribes both for IVF cycles. PIO at night, supp in the morning. I think I would prefer to do the shots all the time, but this is how they do it and it isn't that bad.

theworms · October 2010

both of the clinics i've been at (cor.nell and sirm) prefer PIO injections. sirm actually does a PIO shot and supp combo.

GL

abbe19 · October 2010

I am so glad you asked this. Just talked to my RE office today about starting everything up and she mentioned that I have the choice between the shot and the supps. Thanks for everyone's input!

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