I'm looking for suggestions/thoughts/comments...whatever.....
So for my two previous (failed) IVF's, I never had a choice regarding how many to put in. I only ended up with 2 on day 4 (IVF 1) and 2 on day 5 (IVF 2). So we put in 2 each time.
This time the RE recommends a 3 day transfer. Most of my mature eggs didn't fertilize. I'm 36, this is my last IVF and I apparently have a major egg quality issue (1 previous pregnancy lost due to chromosomal abnormality)and DOR.
As of today, I have 4 4-celled embryo's that are growing well. A few others that are still 2-celled. Who knows what tomorrow will bring.
Would you put 4 in? My RE says definitely 3 and 4 is a possibility....but she wants me to think about it and decide tomorrow.
This is my last IVF attempt so a singleton would be a dream, but I'd love to have any amount of kids. I've always wanted a big family. Finances are not a problem. It is the safety of it all that is my concern.
Thoughts?
Re: ET - what's the max that you'd put in?
It such a personal choice - so many factors to weigh in. So - here is my simple opinion
If it was me, if I were 36 and this were my last IVF after 2 previous failed IVFs and the ET was on day 3, I would transfer 3.
Started TTC 05.08
Me: Stage II endo, borderline high FSH
DH: perfect
1 lap, 5 IUIs = 4 BFNs and 1 c/p
2 IVFs, 2 FETs = 1 BFN, 1 c/p, 1 ectopic and finally a sticky BFP in May 2011!
1 FET in Aug 2013 = BFP!
Obviously it has to be your call. But 4 scares the crap out of me! I think 3 might be a good option if your RE recommends it, and if you are ok carrying triplets should they all implant and stick. I think you have to be ok with the possibility of the financial and emotional toll of triplets/twins too, but you said that you are ok there. I would just be really concerned about carrying 4 babies-That's how I see it anyway!
GL with whatever you decide though!
My max in your situation would likely be 3.
Best of luck with whatever you choose!!
TTC since August 2008
IVF#1: BFFN; IVF#2: BFN; FET with new RE: BFN
IVF#3: ER 1/15; ET 1/20; Beta#1 1/29: 339!
Twins girls born via c/s at 37w/3d!!
"Let it go, this too shall pass."
I may be crazy, but if it were my last attempt and I had zero implantation on 2 prior transfers of 2, I would probably do 4. But, I guess it may also depend on the quality of the embies on day 3 of this cycle versus day 3 of the prior cycles. If they are all doing better, then I may only put 3 back.
With your history, I would think it would be a very low possibility that all four would stick (or for that matter, even 3). I did a day 5 transfer of 2 expanding blasts on my first IVF cycle (which didn't work). At that point my RE was willing to transfer all 3 of our day 5 blasts. Since it was our first cycle and all three blasts were high quality, I wasn't comfortable with transferring more than 2. With the next cycle, I may be willing to transfer 3. Since my clinic does day 5 transfers, I don't think I would do more than 3.
Good luck with your decision and with the rest of your cycle!
~SAIF/PAIF/Everyone Welcome~
Me= 37 and DH = 41
Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)
IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN
IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.
IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132. Lil is here!
TTC#2: Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.
IVF #4: BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN
IVF #5: MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN
IVF #6: (New RE): Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN
FET#1: BFN
It depends on the embryo grading on cd3, no way to judge without that information.
But I am AMA also, and if this were my last stab at IVF with 2 failed previous cycles, I would lean toward being aggressive.
Good luck in your decision.
TTC in 2008. Stage II/III endo, Hashimotos hypothyroid, low morph (3%).
2 cycles Clomid/Ovidrel/TI/Crinone=BFN.
IUI #1 - 4 Follistim/Ovidrel/IUI/Crinone = BFN.
IVF #1 - Antagonist w/ ICSI 4/10. 17 retrieved, 5DT of 2, BFN
IVF #2 - Long Lupron w/ ICSI 6/10. 15 retrieved, 3DT of 2, BFFN!!
Lap 7/21/10
IVF #3 - Clomid/Antagonist w/ ICSI 10/10. 14 retreived, 3DT of 3, BFP 10/20 but m/c. No HB 11/15/10 - D&C 11/17/10.
FET - 2 blasts, 1 survived the thaw. Transfer 2/19. Beta #1 3/1 375, Beta #2 3/3 885, Beta #3 3/8 4261, Beta #4 3/11 9005. U/S 3/8 1 sac 1 yolk, U/S 3/16 1 heartbeat 114bpm!
James born Oct. 24th 2011 via c-section at 38 weeks!
Surprise BFP - Jack born April 28, 2013 via VBAC after PTL at 33 1/2 weeks!
Thanks for all of the comments. They all make sense to me, which is the crazy part!
I can't wait for my husband to come home so we can have this discussion. I wish I had more time to think about it.
Thanks again. I'll post tomorrow after the transfer.
This exactly.
Me - DX Hashimoto's Disease, Hypothyroid, Rheumatoid Arthritis
DH - DX Azoospermia - Sertoli Cell Syndrome
DS-IUI #1-4 BFN IVF #1 - BFP! It's a boy!!!