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Anyone heard of Dexamethasone?

orange682orange682
in Infertility

My RE wants me to try Dexamethasone with 150 mg Clomid (days 3-9) this cycle. Clomid was unsuccessfull in the past (i ovulated late) but he thinks that my 15 lb weight loss makes it worth trying again. It's my understanding that Dex helps with egg quality, and thats about all I know about it.

I'm trying to avoid Dr. Google, since that always freaks me out, but does anyone know anything about this medicine? We're gearing up for an IUI and have been for months- I just don't seem to be having a strong enough ovulation and every cycle has been canceled.  Has it helped anyone have a stronger ovulation? 

 

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Re: Anyone heard of Dexamethasone?

  • STL34STL34 member
    My RE puts IVF patients on Dex.  I take .75 mg of Dex per day.  It is administered to decrease inflammation and reduce inflammatory response of your body to foregin bodies (i.e. embryos). 

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    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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  • k-martk-mart

    Well, this was on explination I found:

    I.  DEXAMETHASONE (Decadron)
    Patients who are found to have an immunologic problem (presence of certain antibodies) that could be potentially affecting their fertility will be given a course of this steroid medication. Steroids work by suppressing the body?s response to detected antibodies

    My dr puts me on it and has not tested for antibodies - so I'm actually not sure if it's a combination of the antibodies and the inflamation.

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  • Tab2710Tab2710

    imageSTL34:
    My RE puts IVF patients on Dex.  I take .75 mg of Dex per day.  It is administered to decrease inflammation and reduce inflammatory response of your body to foregin bodies (i.e. embryos). 

    This.  :)

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  • etoyamaetoyama member
    I'm on it as well for my IVF cycle. I have Crohn's Disease (an autoimmune, inflammatory disease)
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  • Just AnythingJust Anything member
    I was put on 1 mg of dexamethasone while I was on clomid.  My understanding is that it suppressed the androgens that my body was producing.  Because of that production, I was not ovulating.  After they put me on this medicine, I did ovulate.
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