Clomid Questions (Low progesterone)

Morty27 · July 2010

First Question: I have had two miscarriages and recently discovered I had low progesterone. My FSH and estrogen levels were tested and that all came out fine. The doctor wants me to do the clomid challenge to see how I would respond to medication. He prescribed 100 mg a day. I did some research and found most doctors start you off at 50mg. I am very concerned about side effects as my body is very sensitive to medication. Did anyone start at 100 mg and still get pregnant? I ovulate on my own regularly every month.

Second Question: The doctor has discovered that I have low progesterone as noted above. Has anyone used fertility drugs like clomid to increase progesterone levels, i.e. to get a better ovulation, and got pregnant?

jeannaqueena · July 2010

I got PG on my own the first time and the egg split and we had identical twin boys (we were about to start clomid that next cycle). This time we were impatient and I did 50mg of clomid CD3-7 and we got PG! They never tested my projesterone b/c I was able to carry the twins with no problems (we lost them due to identical twin complications with the cord implantation). Good Luck to you!

You might try the Success after IF board too! This board has women who have gone through IF and some who can conceive naturally.

JamieFL · July 2010

I also ovulated on my own when my OB put me on 50mg of Clomid. She did this because of my age (35) and the fact that we were trying for several months with no success and to give DH's sperm "more to aim at" if I should release more than one egg.

I was also placed on progesterone suppositories prior and during the time that I did clomid (100mg, inserted nightly from 2DPO until my period or a positive PG test).

It took 2 cycles on Clomid to get pregnant with our miracle. I'd be curious why the higher dosage of Clomid for you to start on, though. It is a doozy with symptoms, I will warn you. Also, if you are on Clomid, definitely get some Preseed (sperm-friendly lube) because Clomid truly dries up your cervical mucus. I attribute Preseed for our positive test on month 2 of trying Clomid - I didn't know this side effect the first month and learned quickly!

GL!

Heidisean · July 2010

HMM, if you ovulate on your own and don't seem to have difficulty getting pregnant I wonder why your OB put you on clomid as there are side effects that are negative also to taking this drug. I would hope this doesn't make you release a bunch of eggs:) As for the progesterone, I had low progesterone and clomid does not increase it....you would need to be on prometrium or a progesterone supplement either orally or vaginally (there is also topical but don't know anyone who took that to help). I was on 2 100 mg vaginally inserted pills of prometruium from prior to getting pregnant (3 dpo) until 13 weeks. I would start my prometrium prior to even knowing that I was pregnant each cycle and when my period would come I would stop and wait until the next cycle. You also have to be careful with prometrium as if you take it before you O it will stop you from o'ing. Infertility sucks! GL to you!

Mrs.Brink · July 2010

We were in the same situation. I ovulate like clock work but have low p4 (peaked at 5 with no meds). Our ob put us on 50mg clomid though for a better egg quality (apparently I make sad tiny ones). My p4 doesn't hold so I had to be on 200mg vag. suppositories 2x's daily. On clomid alone my levels got up to 19.1 but my body couldn't sustain for pg, 2nd loss. This current pg we were on 50mg clomid and the 200mg prometrium. I did release several eggs but twins run on my side of the family...didn't know this until after we told my mom (a cousin is also pg with twins right now). Now we just wait to see if they're identical or not.

Heidisean · July 2010

Mrs.Brink:
We were in the same situation. I ovulate like clock work but have low p4 (peaked at 5 with no meds). Our ob put us on 50mg clomid though for a better egg quality (apparently I make sad tiny ones). My p4 doesn't hold so I had to be on 200mg vag. suppositories 2x's daily. On clomid alone my levels got up to 19.1 but my body couldn't sustain for pg, 2nd loss. This current pg we were on 50mg clomid and the 200mg prometrium. I did release several eggs but twins run on my side of the family...didn't know this until after we told my mom (a cousin is also pg with twins right now). Now we just wait to see if they're identical or not.

Wouldn't they not be identical since they are in 2 different sacs? I thought identical twins are in the same sac.

E&RMommy · July 2010

Did he do the clomid challenge test or is he prescribing clomid to try and conceive this cycle?? Those are two very different things.

Mrs.Brink · July 2010

Heidisean:
Mrs.Brink:

We were in the same situation. I ovulate like clock work but have low p4 (peaked at 5 with no meds). Our ob put us on 50mg clomid though for a better egg quality (apparently I make sad tiny ones). My p4 doesn't hold so I had to be on 200mg vag. suppositories 2x's daily. On clomid alone my levels got up to 19.1 but my body couldn't sustain for pg, 2nd loss. This current pg we were on 50mg clomid and the 200mg prometrium. I did release several eggs but twins run on my side of the family...didn't know this until after we told my mom (a cousin is also pg with twins right now). Now we just wait to see if they're identical or not.

Wouldn't they not be identical since they are in 2 different sacs? I thought identical twins are in the same sac.

I thought this too...and still think ours our fraternal. ID's can still have their own placenta/sacs if the split happens early enough. I got some "lovely" pm's from the multiples board telling me how wrong I was to think they're fraternal. But we were on clomid so it's more likely that they are.

Morty27 · July 2010

I should have been more clear - yes, I am doing the clomid challenge test. I called the doctor and turns out I have to do 100 mg to do the challenge. Although, now I am not understanding why I have to do the challenge because my FSH came back good.

Ad.Interim · July 2010

With my 1st pregnancy, I had very low progesterone, but everything else checked out okay, so, like Heidisean, I was just put on Prometrium (200 mg/day oral). I got pregnant the first cycle I took it.

chutch831 · July 2010

I was ovulated on my own but had low progesterone and a short LP (usually 9 days). My OB discussed clomid to increase my progesterone level and was going to start with a new cycle. However, things happened and I ended up ovulating very early and there was a possibility I could be pregnant, so I took prometrium starting 4 days after O. Turns out I was pregnant, didn't need the clomid and just took the prometrium until 12 weeks. I also take baby aspirin for blood clotting. My little boy is doing well and should be here shortly! Good luck to you! I know it can be confusing and it's hard to know what to do.

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