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IVF and Estradiol Level Issue

ufrowerufrower member
in Infertility

Hi ladies -

I don't come on here a tremendous amount, but when I do you ladies are always so helpful with information and support.

So a little background -- I am 33, husband is 36. No known medical issues. Have had every test under the sun - all came back normal for both of us. Only thing was that my AMH was 1 and my antral follicle count was 10 (5 on each ovary).

We did about 8 IUIs. Currently I am doing my first IVF. I did 10 units of Lupron for about 10 days (along with BCP). I dropped down to 5 units of Lupron when I started stims. I started stims 4 days ago -- 225 of Menopur and 225 of Bravelle. Just went in today for my first estradiol level check (no ultrasound yet) and I am only at 83 (should be at 200-250). They are increasing my Menopur and Bravelle to both being 375. I go back in 3 days for an ultrasound and I guess at that point they will decide whether to continue.

Now my issue is that when I did my IUIs with Follistim, I always responded with at least 4 follicles. What could cause me to not respond to the Menopur and Bravelle?  Also, with the increase in dosage -- do I need to worry that I am going to a lot less eggs and that my eggs are going to be crap?

Thanks for any information or support that you can provide. I am starting to freak out a little bit that the cycle might be cancelled or that I am already doomed to have a negative result.

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Re: IVF and Estradiol Level Issue

  • Ginger71Ginger71 member

    BCPS and Lupron supress you so that your follies don't grow too fast. With IVF, they want to grow the follies slower so the quality is better. You can add more drugs if you need to but you can't reverse follie growth if you are given too much meds.

    I don't think you are not responding....I wouldn't say that yet. I have had cycles where it looked like nothing was going to grow one day and all of a sudden I am ready to trigger.

    I wouldn't worry yet. GL!

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  • ufrowerufrower member
    Thanks so much! I am trying to stay positive, but god, it gets hard sometimes!
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  • Ginger71Ginger71 member
    I know! GL! :)
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