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Lupron Trigger

Houston2010Houston2010
in Infertility

Hello Ladies,

Anyone have any experience with lupron as a trigger? My RE thinks that it will help prevent OHSS and that i will be in a lot less pain after ER if i use lupron as a trigger. Also what was your dose? Thanks!

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Re: Lupron Trigger

  • LCB34LCB34 member

    Kimarino did this with her first IVF I believe - not sure of the dose though.  She did it for the same reasons you have mentioned.

    I see you are in Houston - who is your RE (if you don't mind sharing)?

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  • SarahandAngelSarahandAngel
    I am confused. How could Lupron be used as a trigger. It is the opposite b/c it is a supressing drug. Maybe they meant kept you on Lupron until you trigger???
    TTC#1 since 7/07 with MFI and Endo/PCOS IUI #1 and #2 with 50mg of clomid= BFN IUI#3 with 100mg of clomid and Bravelle= BFN Lap surgery 11-18-09= found Stage IV Endo :( Three months of Depot Lupron Shots and adding 2000mg Metformin IVF w/ ICSI May 2010 = BFP, M/C at 6 weeks Break to lose weight, down 60 pounds and gearing up for IVF #2 in August 2011
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  • LCB34LCB34 member

    imageSarahandAngel:
    I am confused. How could Lupron be used as a trigger. It is the opposite b/c it is a supressing drug. Maybe they meant kept you on Lupron until you trigger???

    I don't quite understand it either but, when a certain dose of Lupron is given, it can act as a trigger. 

    The thought behind using it is that HCG makes OHSS worse so, if you are at a high risk for OHSS, trigger with HCG can make is that much worse so they aviod injecting HCG into the system.

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  • Houston2010Houston2010
    I see Dr Gill @ HFI. I made a last minute switch from HIVF.
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  • Houston2010Houston2010

    imageSarahandAngel:
    I am confused. How could Lupron be used as a trigger. It is the opposite b/c it is a supressing drug. Maybe they meant kept you on Lupron until you trigger???

     

    Not sure either how it works but my RE said that i was at risk for OHSS and so he decided to use the Antagonist protocol so that i could switch to Lupron trigger if my levels were high.

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  • LCB34LCB34 member

    imageHouston2010:
    I see Dr Gill @ HFI. I made a last minute switch from HIVF.

    That was my clinic too!  I LOVE them!  I saw Dr. Witz! 

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  • Houston2010Houston2010
    imageLCB34:

    imageHouston2010:
    I see Dr Gill @ HFI. I made a last minute switch from HIVF.

    That was my clinic too!  I LOVE them!  I saw Dr. Witz! 

     

    I saw him at my appointment on Wednesday. He seems quite nice and level headed. I have had a great experience at the clinic so far and i pray it stays that way.

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  • LCB34LCB34 member
    imageHouston2010:
    imageLCB34:

    imageHouston2010:
    I see Dr Gill @ HFI. I made a last minute switch from HIVF.

    That was my clinic too!  I LOVE them!  I saw Dr. Witz! 

     

    I saw him at my appointment on Wednesday. He seems quite nice and level headed. I have had a great experience at the clinic so far and i pray it stays that way.

    Let me know if you have any questions!

    They have a great track record on this board!  I really think it is their amazing embryologist that makes all of the difference!  Good luck!

     

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  • c0debabec0debabe

    I did a Lupron trigger b/c I was overstimmed (we got 39! eggs at ER).  I did 3/4 cc 12 hours apart.  I was bloated and miserable, but after ER I started to feel better. 

    From what I understand, the Lupron trigger helps prevent OHSS because it destroys the corpus luteum instead of letting it hang around and secrete fluid.

    DS #1 on the way after 2 cycles of ART (IVF+FET) EDD 7/3/11
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  • Houston2010Houston2010
    Thank you so much ladies.
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  • SarahandAngelSarahandAngel
    Very interesting. good to know. I am always learning from you ladies Big Smile
    TTC#1 since 7/07 with MFI and Endo/PCOS IUI #1 and #2 with 50mg of clomid= BFN IUI#3 with 100mg of clomid and Bravelle= BFN Lap surgery 11-18-09= found Stage IV Endo :( Three months of Depot Lupron Shots and adding 2000mg Metformin IVF w/ ICSI May 2010 = BFP, M/C at 6 weeks Break to lose weight, down 60 pounds and gearing up for IVF #2 in August 2011
    Report Reply
  • cowgirltncowgirltn member
    I did it this time because IVF #1 i had OHSS and it sucked. I had my ER retrieval today and feel much better then the 1st time. My E2 was 4000+ less then the 1st time. 
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  • Houston2010Houston2010

    imagecowgirltn:
    I did it this time because IVF #1 i had OHSS and it sucked. I had my ER retrieval today and feel much better then the 1st time. My E2 was 4000+ less then the 1st time. 

     

    Glad to hear that you are feeling better.

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