I have severe major depression and was put on Zoloft.
I took 25 mg for 6 days, 50 mg for 10 days, 75 mg for 2 days and 1 day at 100 mg. So far I haven't felt any better. There are times when I think it is getting worse. I was taken out of work to try to cut that stress out. I go to a therapist weekly but I don't go back to my psychiatrist for another 9 days.
For those on medicine how long did it take until you felt a change?
Thanks.
Re: When will the medicine start working?
They say that it can take up to two or three weeks to really feel the effects of anti-depressants.
That said, when I have found meds that work well for me, I start to feel better in less than a week--not the full effect, necessarily, but I can feel them working. It looks like you are coming up on three weeks. . . I'm pretty sure that if you were to call your psychiatrist now, he would tell you to wait it out. I guess my suggestion would be to talk to your therapist and see what s/he says about it.
When you do go to the psychiatrist, s/he may want to keep you on Zoloft with higher dosages. Personally, I would ask to try something different. I have dealt with depression for over a decade and have been on many different anti-depressants. I think that if a medication is not working at a usually starting amount, why take more of the same thing when there are so many other medications out there.
The only thing I would be careful about is what you can take while pregnant. That limits the options for you, but talk to him and share your concerns.
Best of luck and I hope that you feel better soon!
It may take 3-4 weeks for Zoloft to take full effect. Zoloft is always started at the 25mg dose and then increased after a few days or weeks until a suitable dose is found. The maximum dose is 200mg/day. It takes some time for Zoloft to "build up" and correct the chemical imbalances in the brain. It blocks the body's reabsorption of serotonin, a chemical that is responsible for improving mood. When serotonin reamins in our brain, we feel better.
I started at 25mg for 2 weeks, took 50mg for 2 weeks, and now am at 100mg/day. I felt a huge difference after about a week of the 100mg/day dose.
It sounds like you might need to give your current dose a little more time to work. If you are not seeing improvement after a few days or weeks, call your doctor to see what the best next step would be. If you feel worse, call your doctor immediately!
Good luck!
7 years ago i was put on paxil. i have to be honest with u and tell u it took 3-4 weeks before it kicked in and i felt better and i remember actually feeling worse when i started taking it. my doctor had to prescribed xanax to take the edge off during the first few weeks until the SSRI kicked in.
good luck!