Hello everyone. In short, we are dealing with IF (on my part) and I have had four losses, two of which were multiples. We lost our triplets at 9 weeks on July 19th. I am Hetero FVL and Hetero MTHFR C677t. My RE contributes my losses to my thrombophilias. I was on 40mg Lovenox/day with my second, third (c/p) and fourth loss in addition to BA and the extra folic (4mg/day).
When we cycle again, we are going to try 80mg/day of lovenox instead of 40mg. Also, I start my lovenox early, at 3dp HCG trigger shot (which is about 1dpo). My triplets was the first time we tried this (starting lovenox early) and I can't help but think it may have helped us get farther. My first and second pregnancies were barely 6 weeks and my third was early, a c/p.
I just wanted to check and see if anyone had prior losses on one dose of lovenox but then success once they tried a higher dose. Also would love to hear success stories of starting lovenox prior to implantation. Oh yea, and I am also now on 2000mg Metformin/day for PCOS.
TIA!
Re: Anyone have success after trying a higher lovenox dose?
I have not. I was on it with DD and it was only precautionary so I was on the smaller dose. I just wanted to say I'm sorry for your losses and I hope this larger dose works for you. Good luck.
I've always been on 80 mg twice/day since TTC. When I switched Dr's, my new OB thought that was too high and checked to see if I was therapeutic and I was right in range. My perinatal mentioned to me that many OB's do not prescribe high enough doses to keep you at a therapeutic level. I had one miscarriage a few months prior to this pregnancy (still I was on 80mg twice/day) but couldn't know if it was due to my homozygous factor 5 or not.
I'm so sorry for your losses. I just can't imagine how much emotional pain you've been through. I truly hope you get your miracle soon! GL!