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Femara/Letrozole Protocol

jacmdbjacmdb
in Infertility

We started our first medicated cycle this month and it seems very different than what our women on this board have done.

BCP for 2 weeks

Stop taking BCP today. Next Sunday I take 10 pills of 2.5mg Letrozole. The following Friday I have an u/s. Depending on the u/s, TI on Sunday, Abstain Monday. Tuesday I have another u/s and get my hcg trigger shot and also TI. TI on Wednesday as well. Then in a week they will check my progestrerone. 

Has anyone had a similar protocol? I thought most took the Letrozole like clomid and it was daily for 5 days. 

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Re: Femara/Letrozole Protocol

  • JM1977JM1977 member
    That does sound different... I did use Femara like Clomid (2.5 mg on days 5-9).  Do you mean that you will take all 10 pills next Sunday or that you will start on Sunday taking 2.5 mg per day?  Did your dr. give you a reason for taking the BCP before starting on Femara?  Sorry I'm not familiar with the protocol you're doing, but I wish you the best!
    TTC with DOR, low morphology, fertilization issues
    IVF#1 Oct 2009 (CCRM) - BFN
    IVF#2 March 2010 - Poor response/cancelled
    DE IVF#1 Aug 2010 - BFN
    DE IVF#2 Dec 2010 - Transferred 1, 2 frozen - BFP!
    TTC#2 FET Jan 2013 - Transferred 1 - BFP!

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  • jacmdbjacmdb

    According to the paperwork I have, BCP are for ovarian down regulation which prepares the ovaries for the hMG stimulation.

    Yes, I take all 10 pills on one day. 

    I thought this was different than the usually protocols on this board. 

    I guess we will see what happens in the next few weeks!

     

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  • JM1977JM1977 member
    Yeah, that seems like a lot in one day, but there must be a reason for it....  I hope you have success with this protocol.  Good luck with everything!
    TTC with DOR, low morphology, fertilization issues
    IVF#1 Oct 2009 (CCRM) - BFN
    IVF#2 March 2010 - Poor response/cancelled
    DE IVF#1 Aug 2010 - BFN
    DE IVF#2 Dec 2010 - Transferred 1, 2 frozen - BFP!
    TTC#2 FET Jan 2013 - Transferred 1 - BFP!

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  • katieranck2202katieranck2202
    I do something similar. I confirm a BFN with a hpt before taking my Femera and I take all 10 pills on cd2 and then go from there until ovulation where I take HCG injects 3dpo, 5dpo, 7dpo, and 9dpo. I questioned my doc about that too and he said that the femera works just as well taken all at once instead of over 5 days.
    Katie, PCOS since May 2005, Fostering since November 2010 Adoption since December 2011 Baby Birthday Ticker Ticker
    *PCOS bio* *Cold Hands, Warm Heart*
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  • slizsliz

    I took 2 pills a day for CD4-8 both times...so taking them all at once seems a little weird to me...

    plus I thought femara was supposed to leave your body very quickly - so if you took all 10 pills at once, wouldn't it be metabolized and excreted before your follies had time to mature?

    the second time I spotted past AF until CD12

    This month is after the second round of femara and I am also experiencing post AF spotting

    so for me the femara definitely affects my estrogen levels (which it is supposed to) and my lining (which it is not) :(

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