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IVF Quesiton #2 ~ Preimplantation Genetic Testing

Ruby_TuesdayRuby_Tuesday member
in Infertility

Has anyone considered or done this?  What are you thoughts on it? 

I'm not sure if it would be covered with my insurance and I'm not sure I want to pay the extra $5,000 for it.  But I kind of like the idea of only transferring embryos that have been tested and are probably free of chromosome abnormality.  I'm 35.  And it's possible that my CPs have been the result of chromosomaly abnormal embryos, although who really knows.

On the other hand, on a gut level it doesn't sound like such a great idea to remove one cell from my 6-10 cell embryo. 

jailbirds Lilypie Second Birthday tickers
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Re: IVF Quesiton #2 ~ Preimplantation Genetic Testing

  • pria2004pria2004

    ...sorry dont have ans for you...but just wanted to say I lvoe your home...stone and wood....lovely....is this ur home in philly???

     

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  • pria2004pria2004

    okie...i may have some info....PGD only checks for few chormosomes...(i think 9) and it is done on Day 3 embryos.....howeevr CGH testing is done on embryos after Day 5/6 and a placenta cell is removed and all 23 chromosomes are tested....personally if I leaning towards genetic testing,i would do CGH instead of PGD...I am sure you can google up for more opinions. I know CCRM ad SIRM do CGH...

    Also for recurrent miscarriages, have you had other testing like RPL etc done? to make sure you and DH dont carry anything wrong in your chromosomes or blood?

     

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  • *Willis**Willis*

    I haven't done IVF, but I did ask my RE about IVF with PGD at my last appt post-m/c.  My RE said that there was a time when clinics did PGD for everyone, thinking it would rule out chromosomal abnormalities.  However, a recent study was published in one of the leading journals that basically said your chances are the same for m/c even with PGD.  Apparently, PGD is best used for parents who may be carriers of a certain disease (CF, etc), and not just for ruling out possible abnormalities.  My clinic only recommends it for this situation now, and a patient (who isn't a carrier) must really insist on it before they will do it.

    In short, he didn't think it would be a fix for me.  I thought it was interesting.  Even after two losses, he thought I should continue with injectable IUI's for a bit.  

    Good luck!  Any idea when you will start?

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  • Ruby_TuesdayRuby_Tuesday member

    Thanks about the house!  Yes that our home in the Philly area.  We are out in the western burbs and the contemporary homes seem to be popular near us.

    My RE only talked to me about PGD then he said something about some doctor's getting carried away with the testing...

    I've had all the RPL testing done and the only thing they found was the A version of MTHFR which is not supposed to be the 'bad' one. 

    Thanks for responding!

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  • Ruby_TuesdayRuby_Tuesday member

    Willis ~ That's interesting.  The literature that my RE gave me said that it did reduce the instance of m/c.  But when he spoke to me he sort of poo-pooed the procedure.  He said he preferred what he called 'poor man's PGD' where they wait the extra couple of days before transfering to see how the embryo is doing.  He told me the exact number of days but I don't remember.  He definitely gave me the impression that if it was his family he would not do it.

    I'm on a femara cycle with no IUI this time and it ends (hopefully in a pregnancy-a girl can dream) on 9/15.  At that point my insurance will consider me IF since I have to wait 6 months since the last documented m/c which was in March.  The paperwork says something about cycling quarterly.  So I'm thinking that I could start BCP around Oct. 1.  That was a really long way of saying, "I'm not sure."  Embarrassed

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  • *Willis**Willis*

    I was surprised too, but my RE said this study came out this summer.  He definitely poo-pooed the procedure.  I was somewhat relieved, because it once again proves my RE isn't money hungry.  DH and I were ready to shell out the cash for IVF w/ PGD, and he basically said, let's give injects a few more tries.  But we are OOP and relatively young (28 and 30), so I'm going to give it a go.

    I've got everything crossed you don't make it to IVF :).  I have lurked over on MM forever, so I've been following your "story."  Not to sound creepy or anything!

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  • Ali212Ali212 member
    I just had a d&c last month  and we're starting IVF #1 now.  We are opting for the testing...it can't guarantee everything but it helps avoid some potential pitfalls which I want to do after what I just went through (the cause of my miscarriage, trisomy 16, could have been detected through genetic testing).  It's not cheap - I'm paying $7K out of pocket - but we've decided it's worth it for us.
    5 IUIs | 4 IVFs | 2 sweet little girls Baby Birthday Ticker Ticker Baby Birthday Ticker Ticker
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  • Ruby_TuesdayRuby_Tuesday member
    image*Willis*:

    I've got everything crossed you don't make it to IVF :).  I have lurked over on MM forever, so I've been following your "story."  Not to sound creepy or anything!

    I'm totally taking out a restraining order. j/k Stick out tongue

    I wish you tons of luck with your IUI cycles!

    jailbirds Lilypie Second Birthday tickers
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