Infertility

No Fertilized Eggs - Devastated & Confused

My ER was yesterday & they got 18 eggs.  Today we got the call from the IVF Coordinator saying that none of the 18 eggs fertilized because they were not mature enough.  I am devastated and so confused by all of this.  We were so convinced this would work and this would be the one.

The IVF Coordinator mentioned that I might have PCO (which I always thought was PCOS), but we have to meet with the RE to get the full details.  I did some brief research on PCOS and don't have a single symptom.  I've had text book cycles since I was 11, I'm overweight now b/c of all the fertility drugs but I'm usually a normal weight & size, I ovulate every month, I've had God knows how many ultrasounds & no one has ever said anything about cysts, all my blood work is perfect - I just don't get it.  I guess I could be insulin resistant, I've never been tested for that, but could that prevent me from producing mature eggs?  And why didn't they catch this before we went through the IUIs and IVF?

She said they could put me in the September cycle with new stim meds to help ensure mature eggs, but I don't know if I'm up for it.  DH deploys at the first of October and we would probably get the "results" of IVF #2 only days before he left.  If IVF #2 fails, I don't know if I could take it.  Plus my body has been through so much, I don't know if it's fair to me to start back so quickly.  They can freeze his sperm before he leaves, but I can't imagine going through this without him.  Of course we can wait until he gets back, but he may not come back - it is a war.

I'm just so confused and we're both hurting.  Any PCOS info or stories would be very helpful.  And any stories about immature eggs would be helpful too.  Thanks.

IVF#1 August 2009 - Failed Currently on hold due to DH

Re: No Fertilized Eggs - Devastated & Confused

  • Oh sweetie. I am so sorry. IF freaking blows. ((hugs))
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  • I'm so sorry. I don't have any PCOS stories, but I wanted to send you (((((hugs))))).
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    Unexplained Infertility

    After two Clomid cycles, three injectable IUI cycles, two IVFs, two miscarriages, and one lap surgery, IVF #2 has brought us our little boy!

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    After months of being postponed or cancelled, FET #1.3 (Natural FET) brought us twin girls!

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  • I am sorry that I don't have any experience or stories to share with you regarding your post.  I just wanted to say Good Luck and I am so sorry you are going through this.

    Thanks to you and your husband for all the bravery and fighting for us!!!

  • Im so very sorry. I have PCOS but am just begging my ttc journey.
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  • I am so sorry.  (((big hugs)))
    TTC with unexplained IF since 8/2007 6 losses, one beautiful perfect boy in our arms Lilypie Premature Baby tickers
  • I'm so sorry.  I had a somewhat *simular* situation a month ago, they retrieved 13 eggs and only 3 of them were close to mature, so they ICSI'd them and two did fertilize, but just didn't grow because they were'nt mature enough (full story in blog, see blow).  We are trying again next month, and the dr. is conviced that everything went well in our cycle, but we just triggered too early.  Even though my follicles looked large enough to house mature eggs, they just weren't.  It was really sad.
  • I have no insight on PCOS but I just wanted to say how sorry I am, I'm sure that is such an awful feeling to not know.  Hang in there and ((HUGS))
  • Gosh, I'm so sorry to hear your news, I truely feel for you.  I was diagnosed with PCOS officially earlier this month.  I was pretty sure I had it though becasue my sister has it and I have had such issures with my cycle for so long.  We have been ttc since Oct'07 so we're coming up to the 2 yr mark (ugh)!  I have never skipped a period except for my chemical pregnancy in Nov '07 and my mc Feb '09.  I do ovulate but they don't think I O on a 'regular' basis.  Every so often when I have a  40+ cycle they think it's because it was anovulatory.  I also spot for about 2 weeks before every period.  I will be trying clomid this cycle in hopes of having a 'stong' ovulation.  My dh has been tested and he seems to be fine, so the issues ly with me. Not sure if this helps since it sounds like you're pretty sure you don't have PCOS.  Good luck and I hope what ever you decide works.
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  • I don't have any info on PCO or immature eggs.  I just wanted to say how sorry I am for you for this devastating news. And to have your DH going off to war on top of it all. I can't imagine.

    Take care of yourself and good luck with what ever you decide.

    Ectopic pregnancy Aug. 2008, followed by a diagnosis of two blocked tubes.
    IVF#1 gave us a BFP on 8/24/09, DD born May 2010
    Surprise, natural BFP July 2012 ended in miscarriage 9/4/12 at 10w4d
    FET#1 January 2013
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  • I'm so sorry this is happening to you - how devastating.  ((HUGS))

    I have polycysric ovaries and some symptoms of PCOS, but have never been outright diagnosed with the syndrome (no weight problems, I ovulate on my own, etc.).  They got 40 eggs from me (36 mature) during my IVF cycle, which I've been told by 2 other REs, is way too many.  With PCOS the trick is careful stimming and tweaking to get the right quantity and quality.

    If you're not sure what to do next, go get a second opinion.  I did these past 2 weeks and it has given me my hope back (details in blog).  

    Best of luck to you!

    PCOS, lupus anticoagulant, MTHFR (A1298C, one copy) 2 IUIs & 1 IVF = BFN FET#1 = It's a girl! Born 7.1.10 FET#2 = c/p FET#3 = Twin girls! Born on 3.16.12 at 33w2d due to severe pre-E. After 4 weeks in the NICU they are home! Lilypie Third Birthday tickers
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  • koynkoyn member

    I am so sorry.  Your cycle sounds almost identical to my first IVF.  I had 19eggs retrieved and none of them were mature.  They matured overnight but only 3 fertilized and I had to even wait to do a 6 day transfer with the only one OK blast left.  That led to BFN.  IVF #2 they changed the medication to a lessor dose so they would get less but more quality.  They only retrieved 1 egg which was not mature and didn't mature overnight.  I am completely devastated.  More about it in my blog.

     My RE told me the same thing about reacting like PCOS but I don't have it.  She suggested Metformin because it could not hurt but it may possibly help.  I am still on the fence about using something else but considering it.  

     I would definately give it some thought before moving right into another cycle.   It was really hard to think of not just getting done now, but if the same happens again it could really be devastating.  I wish you luck in whatever you do. 

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  • Thank you everyone for the hugs and well wishes.  They truly do make me feel better.  I have thought about getting a 2nd opinion.  But despite the fact that we live in a pretty large city, there are only two REs in town.  However there are REs in cities within 2 hours of us that I could consult.  I just want to hurry up and talk to the RE to find out exactly what went wrong.

    Oh, and a big thank you for the well wishes for DH.  Thanks again!

    IVF#1 August 2009 - Failed Currently on hold due to DH
  • Just wanted to tell you how sorry I am.
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  • I'm so sorry about your fert. report. I know you must be devastated. Please feel free to PM me if or when you have questions about your future options when dh deploys. We are currently going through our 1st IVF with dh overseas. Thank you and your dh for your sacrifices and I wish you the best of luck with your journey. ((hugs))
  • I feel for you hon-I have no advice re: PCOS but IF is so hard. No one esp people working so hard for our country deserve this! Prayers for you and dh.
  • I just wanted to say how sorry I am that you have to go through this. I hope you get some answers soon from your RE as to what happened.
  • No advice but I just wanted to say how sorry I am.  I cannot imagine how difficult this all is, especially with your DH about to leave again.  Hopefully you can get some answers soon. 
    Dx with PCOS and IR June 2009
    After two losses, third time was a charm.
    pm me for blog link
  • Wow...that is just devestating news.  I am so sorry.  I hope you get some answers, and godspeed to your DH - may he come back quickly and safely.
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  • That sounds exhausting and frustrating...hang in there and big hugs.
  • ((((hug)))).............
  • Oh no, I am so so sorry! What a thing to go through. You are in my thoughts. (((HUGS)))
    Lilypie Second Birthday tickers

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    TTC Since Dec 2006
    *IVF #1 cancelled at ET*
    *IVF #2 OHSS, transfer cancelled*
    *FET #1 2 frosties, c/p*
    *Lap April 2010, removed endometrioma/endo implants*
    *Surprise BFP June 2010*
    *Beautiful daughter born 2/14/11!!*
    Thoughts from an Overwrought Mind
    SAIFW
  • i am so sorry...  there just aren't words.   i hate that you're going through this....
    Brought to you by IVF, ICSI, limited fert, and oocyte cryopreservation.
    Because we're fancy like that.

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  • I am so sorry ((HUGS))
  • So sorry.  Hugs to you and your DH!!

    TTC Since 10/08 4 IUIs=BFNx4
    IVF#1=BFP!! Twins!!
    Bradley and Billy born and lost on 2/2/11 at 19w2d due to pPROM/PTL. I miss you, little angels.
    IVF#2=BFN
    IVF#3=c/p IVF#4=Empty Follicle Syndrome; 1 mature, fertilized, & made it to blast. 5dt of "the lone ranger" on 9/6. Please stick, little one! Image and video hosting by TinyPic Lilypie First Birthday tickers
  • i'm so sorry. big hugs!!!!!
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  • Oh sweetie, I am so sorry.  I have no experience with PCOS...sorry I couldn't be more helpful.  ((( BIG HUGS )))
    TTC #1 w/ endo since Sept 2005. After many losses, a lap, tons of meds and tons of testing and, one failed IVF cycle, we were blown away with a surprise, sticky BFP...it's a girl!!! Lilypie Second Birthday tickers
  • I am so sorry.

    If Atlanta is one of the places you could get a second opinion, you are welcome to stay with us so you don't have to drive both ways in the same day.

    3 yrs ttc, 3ivfs, 4 iuis and finally a baby boy! And then a girl to follow. 2 under 2!
  • I am really sorry. :( I have PCO - it is when you only have it in your ovaries - no other symptoms. In my first 2 IVF cycles, I had very low maturity rates because they didn't let me go long enough before triggering and I got too many eggs too fast. It was a disaster both times. There are specialists out there that work specifically with PCO. I would probably want to meet with your RE and go through the specifics. You don't want him/her to just "think" you have PCO. I would want concrete information on why they think this (is it just immaturity) and how they are planning to change your protocol. How many days did you stim this last time?
    I hate to say I'm a PCO expert, but I have definitely been through the ringer on PCO. If you have any questions, please feel free to page me.

    Good luck!

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  • I'm so devastated for you.  All that work for no result.  I'm so sorry honey.
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  • I am so sorry but I agree with tryingtogetpregnant that you should definitely get a diagnosis for PCO or PCOS.  I have mild POCS (I don't have all of the symptoms) When I got PG in July with Follistim and Timed BD they stimmed me for a long time on lower doses to make sure my eggs were mature.  I will be doing IVF #1 in December the long lupron protocol and the stimming will be the same slower to make sure the eggs mature HTH.
    May 06: Natural PG= m/c, July 09: TI= m/c, November 09: TI=BFN, December 09: IUI= c/p
    IVF#1: start stims 1/26; ER 2/8; ET 2/13= BFN; FET#1: May 2010= m/c *NEW CLINIC Jan 2011* IVF#2: start stims 1/12; ER 1/22; ET 1/27= BFN; IVF#3: TBD
    ~SAIFW/PAIFW~
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