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Tell me about Follistim and/or B2B IUIs

EmptyOven25EmptyOven25
in Infertility

I start Follistim tomorrow (no more Clomid, yay!!).  I'm just wondering what your s/e were/are.  Are they comparable to Clomid?  Feel better?  Worse?

Also... I am thinking about doing B2B IUIs this cycle because this is my last month of summer vacation and I think we should be as aggressive as possible.  What do you know about the pros/cons to doing B2B IUIs??  We are OOP on IUIs, so it will cost around $500 for two of them.

TIA!!

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Re: Tell me about Follistim and/or B2B IUIs

  • nygrl79nygrl79

    Follistim was completely different for me than Clomid.  I was less moody on Follistim and I didn't have hot flashes like I did on Clomid.  However, Follistim made me exhausted and very very very bloated.  I would go to sleep at 9:30-10 p.m. every night after the shot when on a regular night I'm usually up until midnight.  The bloating was very unconfortable for me too and no matter how much water I drank it would not go away.  Follistim didn't interfere with my estrogen (while Clomid did) and as a result I have better lining this cycle. 

    There are mixed research studies on B2B vs 1 IUI.  If money is an issue, I would just go with one IUI if you have no MIF and BD the next day.

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  • MrsWood1228MrsWood1228

    I am in the midst of a Clomid/Follistim and B2B IUI right now. I just had the first IUI done and the second will be tomorrow. So far - great results! I think I stimmed for a total of 6 nights and have one 22mm follie to O today.

    My biggest side effect was mild morning nausea and it wasn't every day.

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  • PoeticJusticePoeticJustice
    I finished my first Foillistim cycle at the beginning of July.  It had a postive impact during my cycle i.e. the best EWCM I have ever had.  It did make me sleepy and I would always take a nap in the early evening.  I ended up with some good follies. HTH
    May 06: Natural PG= m/c, July 09: TI= m/c, November 09: TI=BFN, December 09: IUI= c/p
    IVF#1: start stims 1/26; ER 2/8; ET 2/13= BFN; FET#1: May 2010= m/c *NEW CLINIC Jan 2011* IVF#2: start stims 1/12; ER 1/22; ET 1/27= BFN; IVF#3: TBD
    ~SAIFW/PAIFW~
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  • MrsP71506MrsP71506
    I did not have any side effects with the follistim.  I was on clomid for 6 cycles and I had every bad side effect that you can imagine!  So going to follistim was such a relief.  I actually produced mature follies and had great EWCM.  Like the pp the best I have had in a while!  My office doesn't do B2B IUI so I don't have any advice on that.  Good Luck!! 
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  • 2becomes32becomes3

    I'm on Follistim now for IUI#1, and so far so good.  I little tired, a little bloated, and have had a couple of dizzy spells...although I'm not sure if that's the Follistim's fault.

    I asked my RE about B2B IUI's, and he said he doesn't do them because there is no evidence that shows it produces better success rates.

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  • psychmusetlspsychmusetls member
    omg i was so thankful when they switched me to follistim.  comparatively it's a cakewalk.  i had horrible s/e on clomid.  i get mildly weepy, bloating, and sometimes fatigue with the follistim, but doesn't compare at all to the raging anger, hysterics, migraines, flashes, etc. . . on clomid!
    S/PAIFW
    Tara & Dave - TTC since September 2006
    PCOS - dx 1999 (amenorrhea) | freakishly long fallopian tubes
    Hypoglycemic | thyroid issues | severely anemic
    Multiple Clomid cycles of 50, 100, 150 - absolutely no response
    Follistim 50/100 | Follistim 75/125 | Follistim 100/150 IUI - all BFNs
    Converted IVF - BFP - m/c | FET - BFN | IVF #2 = BFN
    IVF #3
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