The dreaded (but expected) "Unexplained Infertility". I know I don't *want* there to be more - but honestly, I kind of wish there was something else, so at least we'd know why and what would work! What really surprised me was he said he wasn't sure why the original OB (I don't go to her anymore) told me I didn't ovulate, I did - it was just weaker than he'd like to see.
The RE was an interesting character but gave us some good information. As for the game plan, he kind of left it in our court. He said we could do 2 more IUIs with Clomid, then move on to Fermera+IUI, or we could go directly to Fermera without doing more Clomid. I'm not sure what to do - so any suggestions would be great. I seem to respond to Clomid (two mature follicles this round) so I kind of want to try another IUI or 2 on Clomid before moving on - but are there downfalls to this? Also, he said with Fermera he only does cd3 monitoring - no cd12 monitoring unless he combines the Fermera with FSH...is that normal?
Anyway - we have a game plan and a few days (14ish) to think about our next move if need be...
Re: Well, looks like I have a DX now...
Unexplained Infertility super sucks. When I was diagnosed I was immediately happy because all my test came out fine, and then my RE grounded me quickly by saying that made it harder because there was nothing she could fix.
No advice on medication. I've only done Clomid.
GL!
I have no advice on the meds as I've only don't clomid. I did ask a similar question and got some great advice so hopefully those ladies chime in! GL
I am so sorry. We are Unexplained as well, and it sucks.
I just did my first IUI last week, with 100 mg. of Clomid. I responded very well to the Clomid, so we will likely do 3 cycles with Clomid before looking at other options. I know nothing about Femara, so I can't comment on that, but my Dr. said that after three tries of one course of treatment, the odds of success go down, so at that point, we would explore other options. I think that if your RE is reasonably happy with how you responded to the Clomid, it wouldn't be a bad idea to try another cycle with that before switching to injects, but for me that is more a matter of cost than anything.
Sorry I am not much help, but just wanted to let you know that I understand the Unexplained IF and am here if you ever want to vent!
** After 2 1/2 years of Unexplained IF, 2 failed medicated cycles, and 4 failed IUI's - our baby girl came to us through the miracle of Mini IVF! **
Our diagnosis is unexplained IF and it sucks.
If your RE doesn't do mid cycle monitoring, how will he know if you are responding to the femera? Also I assume that means you will time your IUI with OPKs. The only IUI I have done so far was timed with OPKs and it made me a nervous wreck wondering if our timing was ok.
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
glad you guys made it to your appointment today! the snow was nuts here all day!
Me-28, DH-22
TTC since July 2011
ovulation confirmed in blood test
progesterone blood test normal as well as thyroid
saline sonohysterogram all clear
DH SA shows excellent swimmers
Sept 2012,1st round of Clomid 12, 15, 18mm follies:BFN
Oct 2012, 2nd round of Clomid, one 19mm egg upping dosage 100mg clomid for November in hopes of doing IUI-BFN
November 18th 2012, IUI #1-BFN prescribed progesterone supplements for next cycle, monitoring appt Dec 12th.
December 14th- Missed ovulation, doing TI instead of IUI.-BFN
January 11th IUI #2-BFN
IUI #3-Feb 13th=BFP
beta#1 2/25 12dpiui 61
beta#2 2/27 14dpiui 141 progesterone 21.2
Thanks guys! I'm finding myself more frustrated by the dx this morning than I was yesterday. I guess the only thing keeping me calm about it is that we're on IUI #1 and DH has always been convinced that would be what works. So, while I know I shouldn't put all my eggs in one basket, so to say, I do think we have a good chance this month.
Also, thanks to those who said Fermera needed to be monitored too - I thought it did. The RE I'm going to is big on saving costs - but if monitoring needs to be done, then we'd happily pay. Geesh, I thought going to an RE would be easier than an OB - they'd just do what needed to be done!
I was also unexplained until I had a lap six months after first seeing our RE.
How is your lining on clomid? If your lining is a concern then I would switch to femera. My RE likes to see it above 7 during treatment cycles and clomid always made my lining thin.
My lining at the last u/s was 9 on the dot...he said that was a good response...I guess I didn't think to research it to make sure...
9 is great! I might stick with clomid because you responded so well. How were your side effects? I think femera is essentially the same thing but other women have said on here that there are less symptoms with it. I've never taken femera before.
I like to think we're mysterious, not unexplained!
Lol Love it!!
DX: Unexplained
BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121. US at 8w3d measuring on track HR 177. Released form my RE. EDD 12/28