Last Monday (after 3 days of stims) I had seven follies between 8-10mm - E2 147
Thursday (after 6 days of stims) I had seven follies between 10-14mm - E2 311
Saturday (after 8 days of stims) I had six follies at 17, a 14, a 12, and a 10. I did one last stim night that night and triggered yesterday.
I *just* heard from the Dr that my E2 was 482 on Saturday.
Um, wha?! Someone level with me.. am I only looking at 2-3 eggs with that kind of E2?
#*&^#!@&#)~!(*!@)(*!@#(*!@#)(*!@#&!@%$^%!!!!!!!!!!!!!!!!!!!!!
Re: F@%& Me- Low E2 at trigger? DOR girls? Experts?
Me 33 DH 36 Together 10 years, Married 5 years
TTC #1 since 8/2007 with MFI
November 2012 - IVF w/ ICSI #1; 11/28/12 - ER 12 eggs! 11 fertilized! 12/3/12 - ET - transferred 1 AA Blastocyst
Charlotte Hannah -born 8/13/13.
This! I hope someone has an answer for you!!
***signature & ticker warning***
Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!
Him: 29 ~ perfect swimmers
Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
Stopped BCP 4/2010.
Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN
IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
BCP to manage endo from 10/2012 to 12/2012.
FET w/donor embryos #1: 10/2013 Cancelled
FET w/donor embryos #1.2: 11/2013 ~ ET of 2 beautiful blasts on 11/27.
Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt) Beta 4: 8503(19dpt)
Twins with an EDD of 8/15/14! Team Purple
G&B born 6/30/14 at 33w3d via emergency c/s.
If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!
TTC #1 since 1/10
DX: Unexplained/??? MFI issues
Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2013
4w c/p loss 10/29/12 - EDD July 2013
Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal
Moving on to IVF.
IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy
Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14
After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
We are so in love with her.
"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."
Everybody is welcome!!!
Sorry, yes. I forgot to put it's an antagonist protocol. I realize the ganirelix can lower E2 falsely.. but by how much does it lower it? Am I looking more at 3-4 eggs?
DX: DH (30) severe MFI, severely low count & low motility
Me (32): all clear
Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test
Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
2nd SA 6/18/12: sample is "adequate for ICSI"
Plan: IVF/ICSI July 2012!
ER: 7/26/12. 15 eggs retrieved, all mature.
TESE/TESA/aspiration from epididymis, no motile sperm found
froze all eggs, the saga of praying for good sperm continues.
8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
SA 8/17/12: Zero sperm
SA 8/23/12: Zero sperm
9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
All 3 survived the thaw on 11/15/12!
FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
moving on to DS
DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
1st u/s 4/8/13 shows one gestational sac
2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
A/S 7/22/13: IT'S A BOY!!
PAIF/SAIF Always Welcome
[IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]
Ganirelix can reduce E2 levels but I don't know how much it's true for each individual person - it may vary greatly.
My E2s on ganirelix were up in the 1400's or so... so... I'm not sure. We wound up with 5 on one cycle and 6 eggs on another.
I would say that both our antagonist cycles produced the best looking embryos we ever had and I did technically get PG on both cycles.
So I know it's crushing to be keeping track of the numbers and feel dismal before a retrieval but try and keep the mentality that it's quality over quantity and your magic bean might be one of those retrieved.
Big hugs.
TTC #1 since 1/10
DX: Unexplained/??? MFI issues
Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2013
4w c/p loss 10/29/12 - EDD July 2013
Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal
Moving on to IVF.
IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy
Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14
After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
We are so in love with her.
"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."
Everybody is welcome!!!
If you didn't trigger until the day after your bloodwork, be assured that your estrogen was higher on your trigger day. I'm not sure how much more, but definitely higher, it's amazing how much the number jumps up in a day or so.
Fingers crossed the trigger is what they need to kick into full gear and mature! Hope you get good news! Hang in there.
Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI (TTC#1 since 2009)
IVFs#1-4: (4/10-2/12) all BFN
Surprise Bfp (9/11) - c/p
DS IUI#1-2 (9/12, 10/12) - BFN
DS IVF: (11/12) - BFN
DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN
FET of 2 day 6 blasts: (12/13) - c/p
DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.
FET 5/14: 1 day 5 hatching blast transferred...another BFFN
Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus
New RE, additional testing reveals elevated NK Cells
FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October
Me 38 MH 41 - TTC since June 2010 - dx with Severe MFI. Straight to IVF with ICSI. IVF #1 - ER 06/13/12 - 9 Eggs Retrieved - 4 ICSI'd - only 2 fert. 06/15/12 - 2DT - 3 cell & 6 cell with fragmentation. Beta 06/29/12 - IVF #1 = BFN. 07/20/12 - WTF Appt -Told by our RE to quit IVF. Second Opinion from RE is good. IVF#2 - November 2012. Estradiol Pills Started 11/6. Stims start 11/16. ER 11/26 - 7 eggs retrieved - all mature. 4 fertilized with ICSI. ET 11/29 Transferred 3 embryos. Beta is 12/10. 1st Beta 81 2nd Beta 160 and 3rd beta 360!!! First U/S 12/21/12 - We saw one beautiful gest. sac. 2nd U/S is 01/04/2013 - H/B 183 02/05/13 - NT Scan - everything looks good and IT'S A BOY! Aiden was born 08/20/2013.
IVF #2 is in progress. ER was 05/12/14 - 11 eggs retrieved, 8 fertilized with ICSI. ET was 05/15/14 - we transferred 3 embryos as we did on the cycle my son was conceived. We were able to freeze 3 embryos. Beta is scheduled for 05/26/14. 1st beta - 111. 2nd beta - 159 didn't double
3rd beta Friday 5/30) - not a lot of hope left. Beta # 3 is 247 - probably ectopic. Beta # 4 is 813 - possibly vanishing multiple sydrome? 06/05/14 - 5w4days - first U/S - we see a gestational sac and yolk - still have hope! 06/17/14 - 7w1day - U/S and saw and heard the heartbeat - Finally! 06/27/14 - 8w4days - Baby and heartbeat look and sound great
EDD 02/01/14 and It's a boy!
"Everything will be okay in the end. If it's not okay, it's not the end."
Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI (TTC#1 since 2009)
IVFs#1-4: (4/10-2/12) all BFN
Surprise Bfp (9/11) - c/p
DS IUI#1-2 (9/12, 10/12) - BFN
DS IVF: (11/12) - BFN
DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN
FET of 2 day 6 blasts: (12/13) - c/p
DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.
FET 5/14: 1 day 5 hatching blast transferred...another BFFN
Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus
New RE, additional testing reveals elevated NK Cells
FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October
Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI (TTC#1 since 2009)
IVFs#1-4: (4/10-2/12) all BFN
Surprise Bfp (9/11) - c/p
DS IUI#1-2 (9/12, 10/12) - BFN
DS IVF: (11/12) - BFN
DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN
FET of 2 day 6 blasts: (12/13) - c/p
DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.
FET 5/14: 1 day 5 hatching blast transferred...another BFFN
Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus
New RE, additional testing reveals elevated NK Cells
FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October