TTC after 35

What form of progesterone are you taking?

My OB has me on Clomid CD 5-9 and prometrium pills CD 16 to end of cycle (or beyond, if we should be so fortunate).  I have been reading a little bit about pills vs suppositories vs shots.  I have read that the suppositories may be more effective, but it's hard to find any great information.  

For those of you on progesterone, what form are you taking?  Anyone found some great research on which form (if any) is most effective? 

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Re: What form of progesterone are you taking?

  • I'm using Edometrin suppositories, they're pretty easy to use and I'm happy to be done with shots for two weeks, but they can get messy, panty liner required. Based on my progesterone levels last cycle they definately work.
    nate and teddy
    Me 41 DH 46  Not actively ttc, surprise BFP on 1/6/11! 4/1/11 m/c our sunshine at 16wks after complications from CVS test. TTC #2 **5th cycle 12/6/11 BFP! Missed m/c at 9 weeks 1/21/12, trisomy 14. Two Chemical PG 3/12&7/12
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  • imagedhreczuck:
    I'm using Edometrin suppositories, they're pretty easy to use and I'm happy to be done with shots for two weeks, but they can get messy, panty liner required. Based on my progesterone levels last cycle they definately work.

    This.

    BFP on IVF #2 6/29/2012. Beta #1 7/3 = 522; Beta #2 = 1180; Beta #3 = 6491 image BabyFruit Ticker
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  • I am using Progesterone in Oil, IM shots once a day.  I see it used more on IVF patients though.  It also varies by clinic obviously since a lot also use crinone.  The benefit they say with the shots is that the progesterone is more easily measured in the bloodstream, and you don't have to deal with messy panty liners. 

    Me:40 AMA, DH:36 0% morph, TTC#1;
    BFP#1 4/2011, MMC 6/2011 11wks Trisomy 13;
    BFP#2 11/2011, CP
    FSH: 17.9, AMH: 2.2
    IVF#1 w/ICSI: ER 4/3: 5R,4M,4F
    ET 4/6 All 4 (1-8A+, 2-8A-, 1-3A) BFP#3
    Two weeks of beta hell = Blighted Ovum
    IVF#2 Aug/Sept: ER 8/27: 4R,3M,3F
    ET 8/30 (1-8A+, 1-6A+)
    Beta#1 9/10: 350; Beta#2 9/12: 796; Beta#3 9/20: 9155
    Expecting Boy/Girl Twins! My babies were born 4/23/13 at 36w1d!

     
     

  • I use Endometrin.  I start it three days after IUI until a negative blood test.  She put me on twice a day this month.  My dr prefers suppositories vs. pills as the medicine is more readily absorbed.  I used to use a compounded waxy suppository and that was a huge mess!  The Endometrin isn't completely tidy, but it is much better than the other stuff!
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  • imageMrsNukem:
    I am using Progesterone in Oil, IM shots once a day.  I see it used more on IVF patients though.  It also varies by clinic obviously since a lot also use crinone.  The benefit they say with the shots is that the progesterone is more easily measured in the bloodstream, and you don't have to deal with messy panty liners. 

    So do you get a nightly shot in the bum?  Does it hurt more than a trigger?

    BFP on IVF #2 6/29/2012. Beta #1 7/3 = 522; Beta #2 = 1180; Beta #3 = 6491 image BabyFruit Ticker
  • imageCountry Girl in the City:

    imageMrsNukem:
    I am using Progesterone in Oil, IM shots once a day.  I see it used more on IVF patients though.  It also varies by clinic obviously since a lot also use crinone.  The benefit they say with the shots is that the progesterone is more easily measured in the bloodstream, and you don't have to deal with messy panty liners. 

    So do you get a nightly shot in the bum?  Does it hurt more than a trigger?

    DH does my shot at 6:30 pm every day, it gives me enough time to walk around before bed time (I find that the progesterone sometimes forms a lump if I end up just sitting on my arse the rest of the night).  Odd days on my left, even days on my right :)  The needle is the same length as my trigger shot needle (mine is 1" vs 1/2" for the sub-q shots).  So to me it feels the same as the trigger shot.  DH is getting very good at giving me my shots, I hardly feel it now.  Massaging the area afterwards helps a lot too.

    Me:40 AMA, DH:36 0% morph, TTC#1;
    BFP#1 4/2011, MMC 6/2011 11wks Trisomy 13;
    BFP#2 11/2011, CP
    FSH: 17.9, AMH: 2.2
    IVF#1 w/ICSI: ER 4/3: 5R,4M,4F
    ET 4/6 All 4 (1-8A+, 2-8A-, 1-3A) BFP#3
    Two weeks of beta hell = Blighted Ovum
    IVF#2 Aug/Sept: ER 8/27: 4R,3M,3F
    ET 8/30 (1-8A+, 1-6A+)
    Beta#1 9/10: 350; Beta#2 9/12: 796; Beta#3 9/20: 9155
    Expecting Boy/Girl Twins! My babies were born 4/23/13 at 36w1d!

     
     

  • I'm on Crinone 8% suppositories.  I started them CD21 after IUI on CD18.  They aren't too terribly messy.
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  • I was given suppositories, but instructed not to start to use them until after I have confirmed BFP. 

     I don't know what the side effects, nusances are yet, since I haven't had a chance to use them.... 

    P

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    Breast Cancer diagnosis 12/01/2010 - Survivor and Cancer free as of 03/22/2011
    BFP#1 04/12/201
    1 - fetal demise - MC 05/28/2011
    BFP#2 10/14/2011 - fetal demise - MC 12/13/2011
    BFP#3 05/30/2012 - fetal demise - MC 07/23/2012
    IVF#1 02/14/2013 - 2 Beautiful Blasts transferred
    BFP#4 02/25/2013 - BFP - MC and ectopic 03/06/2013

    IFV#2 07/02/2013 -BFP#5 - 07/07/2013
    1st Beta 07/11/2013 - 483 (9dp5dt) - 2nd Beta 07/13/2013 1006 (11dp5dt)
    1st U/S 07/31/2013 - TWINS! "The Minions"
    IVF#3 BFP#6 09/01/2015 6dp5dt
    1st Beta 09/05/2015 - 105 - 2nd Beta 09/08/2015 335
    1st U/S 09/22/2015 - .......

  • imagelindaeverly:
    I'm on Crinone 8% suppositories.  I started them CD21 after IUI on CD18.  They aren't too terribly messy.

    One more person using Crinone 8% gel. So far it has lengthened my LP (which was 5/6/8 days depending) -- I'm 9DPO, so that's a thing. I have no side effects from them so far (I'm still nursing so I'm not sure I'll experience the breast soreness anyway) other than CRAZY RAGE. But that could be any number of things. :)

    Not really messy at all. 

  • For non-IVF cycles, I've been on the prometrium pills, but used them as suppositories. They must be doing something because even one a day extends my luteal phase from 11 days to indefinite. 

    I've only heard of the shots being used in IVF or FET cycles.

    I'm pretty sure the endometrium suppositories are the most expensive of all the options. The PIO shots are the cheapest.

  • Can you fill me in on this...you literally stick the little pills in your vagina?  I didn't know you could do that!
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  • Hmm. Maybe they're not the same thing. I thought they were. I have Prometrium (progesterone, USP) 200 mg capsules. To be inserted vaginally 2X a day. They are yellow and say SV2 on them.
  • imageReeceFamily:
    Can you fill me in on this...you literally stick the little pills in your vagina?  I didn't know you could do that!

    Yes, for my IUIs they gave me pills that some people take by mouth but I had to stick them in my vagina.  For the IVF, It is a really hard tablet that is about an inch.  It goes in with a plunger.

    BFP on IVF #2 6/29/2012. Beta #1 7/3 = 522; Beta #2 = 1180; Beta #3 = 6491 image BabyFruit Ticker
  • imageReeceFamily:
    Can you fill me in on this...you literally stick the little pills in your vagina?  I didn't know you could do that!

    The Crinone is a thick liquid that comes in a pre-filled applicator that is kind of like a tampon, but smaller.  You sqeeze the pouch & you're done without having to touch anything.

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