Infertility

On Clomid - Had ZERO follicle growth over three days!??

I had a follicle check last Tuesday and the largest was 10mm (this was CD 12) so they told me to come back on Friday. On Friday they were... still 10mm!! (CD 15)

I took Clomid CD 4-9, and I typically ovulate late - like CD 21 - but not when I'm on Clomid. They told me do the at home ovulation tests for the rest of this cycle. My assumption is that it is due to stress... I have to drive two hours to my RE's office, and had to go without my hubby both times. I also had to be there between 730-830am - so I had really crappy sleep too. I'm on CD 18 now and still no surge detected. She wants to double my dose of Clomid next cycle to 100mg - not looking forward to that!

The crazy thing is, I have never had this happen before - there was always some growth between scans. I'm just really hoping this cycle isn't a bust!!! :(

Anyone else use Clomid and not have growth/ovulate?

Me: 32 DH: 38 TTC for 4 years (total) Me: PCOS, Low Progesterone, Factor V Leiden Thrombophillia (fancy for genetic blood clotting disorder) I've had 4 miscarriages, two with my current DH, and two in my previous marriage. Unfortunately, I am the common factor here! *3/2012: Clomid CD 4-9, awaiting ovulation!! *1-23-2012 BFP! Unfortunately without Progesterone supplements early on, M/C 1-30-2012 *3-2010 BFP! Low progesterone, small gest sac, m/c 4-2010 at 9 wks *9-2008 BFP, Tried Myofacial Release Therapy and Daily Progesterone Injections. m/c 10-2008 at 9 wks *9-2007 BFP, Clomid, Estrace, Gonal F injection, Progesterone suppositories. m/c 10-2007 at 7wks

Re: On Clomid - Had ZERO follicle growth over three days!??

  • I actually just had my second IUI cancellled today due to no growth. In Feb I had 2 follies that were a 12 and one to small to measure, and that was on Clomid 50mg. This time we used 150mg clomid and I had one follie at a 7. Its super frustrating, Im sorry your not getting a good response. Hopefully they figure it out soon.
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  • Yep... Clomid was a big old joke for me. Might as well have eaten a packet of tic-tacs.  I was even on the highest dose that they give and NADA.

    My RE decided to try the drug Femara and it grew one little 22mm follicle. Our IUI wasn't successful, but I DID ovulate the one cycle we used it for. We just started another cycle a few days ago, and we'll try the Femara again.

    I see that you're military as well. My hubs is AD Navy right now and I know exactly how much it blows to have to do so many steps of this process A.L.O.N.E.

    Let me know if you need to vent about all things Tricare... cause IF isn't enough of a challenge   :0)

    image
    Dx Hypothyroid 2009 - Dx PCOS 3/2011- TTC since March 2010
    DH: Perfect
    April 2011 - HSG - Normal/Clear but tilted uterus
    May 2011 - Start Metformin
    June 2011 - SIS - Arcuate but normal uterus
    July 2011 - 100mg Clomid Cycle cancelled - No response
    August-September 2011 - Break for oral & eye surgery
    Oct 2011 - Femara 7.5mg + Metformin 1500mg + Novarel trigger + IUI #1 = BFN
    Nov-Mar 2012- Break due to DH ship schedule
    April 2012 - Femara 7.5mg + Metformin 1500mg + Novarel trigger + IUI #2 = BFFN
    May 2012 - Femara 7.5mg + Metformin 1500mg + Trigger + IUI #3 = BFFN
    June 2012 - Femara cycle cancelled - No response
    Jul-Aug 2012 - Break, getting our financials in order
    September 2012 - IVF w/ ICSI and AZH
    9/11/12 - ER (34 retrieved, 24 mature, 18 fertilized)
    9/16/12 - ET - 5dt of 2 perfect blasts and 7 frosties!!!
    Beta #1 - 10/1/12 - BFP!!! 2000+
    Beta #2 - 10/3/12 - 4881
    Beta #3 - 10/5/12 - 8570
    First u/s - 10/9/12 - 6w0d - 2 sacs!!!
    Second u/s - 10/16/12 - 7w0d - 2 babies with 2 strong hbs!!
    First OB appt - 11/5/12 - "Baby A" looks great, good hb and movement, measuring 10w0d
    "Baby B" stopped growing at 8 weeks :0(
    12/5/12 - Baby looks great at 14w2d - 165bpm heartrate!
    January 4th, 2013 - Lost our Baby Girl, Faith at 18w3d
    Emergency D&C to clear infection
    We love you and miss you little one
    image
  • I'm sorry you're having trouble with clomid.  It's definitely not for everyone so your increased dose next month might give you the results you're looking for. 

    I just wanted to say that you shouldn't stress about your stress.  The stress you described is not anything that should affect your fertility or follicle growth rate/ovulation.  You're doing fine, you just might need to try a few different meds.

    Good Luck!

     
    me 33/DH 36
    ttc since 10/2008; d/x: mild MFI, stageII endo
    ~~PAIF/SAIF Welcome~~
    11 IUI’s = 1 m/c (7w4d)
    IVF#1 January 2012 BFN, FET #1 April 2012 BFN
    Surprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)
    IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762
    U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160
    Stick Frogger Stick! Please!!!!!!!!!!!!!   It's a Girl, EDD April 7, 2014

    BabyFruit Ticker

  • Same thing happened to me. I had lots of follicles but all under 10 that never progressed. Finally by cd16, my RE decided it was a lost cause. She immediately switched me to injections though, and they've worked really well for me!! Good luck!!
    Me: 33, Endocrine issues & FVL       DH: 32, Nothing 
    NTNP 2009-2012         TTC since 2012:
    • Clomid, 2 IUI cycles, and 5 IVF cycles = BFN
    • FET #1   August 2013 = BFP!     EDD 5/11/14
    • Jack dx at 19w1d with Dandy Walker on 12/16/13
    • Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13
    • FET #2 --July 2014  BFP!  ---  EDD  4/5/15

    Jack has handpicked his sibling up there :)

    My blog about IF and loss ... Kate's IF Blog

            Lilypie Angel and Memorial tickers 

                                                      

                                                                              Lilypie Pregnancy tickers


                  Anniversary





  • My first round of Clomid I had very little growth but by the time we did the second one I had good growth. I havd good growth also for rounds 3-5. Did they have you use the Ovidrel? Is this your first round? I was pnly producing one good follicle the other one was just barley there.
  • I, too, never responded well to Clomid or Femara -- lots of minimal, little follicles each time. I think I maybe ovulated once or twice over the course of six cycles (waste of time!). Lol. 

    TTC Since 11/10 due to Unexplained IF 
    4 Rounds of Clomid, 2 Rounds of Femara + IUI, 2 rounds of IUI+ Injectables (Bravelle + Menopur) = First BFP! TWIN GIRLS!

    November 2, 2012 - Claire (2lbs 8.9oz) and Paige (2lbs 10oz) arrive at 29w3d due to PTL and pPROM at 28w5d 
    Lilypie Premature Baby tickers 
    Lilypie Pregnancy tickers
  • My RE said to just do the at home OPK and to start doing the progesterone suppositories 4 days after I get a surge - and to call and let them know.We were going to do Ovidrel but since my follicles weren't progressing they didn't want to have me keep coming in for scans I think - so it's a-la-naturale this month!

    Good news though - I got a surge today!!! Big Smile I read on some other forums to do the OPK's at noon instead of fmu - I guess because it usually spikes mid-day. Anyway, I got a smiley face today at noon!! :)  On CD 20, so apparently the Clomid didn't really do a thing since this is when I usually ovulate.

    The only thing I'm worried about is that my hubby hasn't felt well the last couple days, so no BD'ing in 3 days!  I was a little upset that he wouldn't just bite the bullet and BD last night - I mean, I've done it plenty of times when I didn't feel well lol. So hoping we didn't miss the window.. I'll catch him when he gets home!!! ;)

    Me: 32 DH: 38 TTC for 4 years (total) Me: PCOS, Low Progesterone, Factor V Leiden Thrombophillia (fancy for genetic blood clotting disorder) I've had 4 miscarriages, two with my current DH, and two in my previous marriage. Unfortunately, I am the common factor here! *3/2012: Clomid CD 4-9, awaiting ovulation!! *1-23-2012 BFP! Unfortunately without Progesterone supplements early on, M/C 1-30-2012 *3-2010 BFP! Low progesterone, small gest sac, m/c 4-2010 at 9 wks *9-2008 BFP, Tried Myofacial Release Therapy and Daily Progesterone Injections. m/c 10-2008 at 9 wks *9-2007 BFP, Clomid, Estrace, Gonal F injection, Progesterone suppositories. m/c 10-2007 at 7wks
  • imageCrystal120410:
    I actually just had my second IUI cancellled today due to no growth. In Feb I had 2 follies that were a 12 and one to small to measure, and that was on Clomid 50mg. This time we used 150mg clomid and I had one follie at a 7. Its super frustrating, Im sorry your not getting a good response. Hopefully they figure it out soon.

    UGH! Yeh it is super frustrating because you are at the mercy of your own body, and what the doctor tells you most of the time! I hope things get better for you too!!!

    Me: 32 DH: 38 TTC for 4 years (total) Me: PCOS, Low Progesterone, Factor V Leiden Thrombophillia (fancy for genetic blood clotting disorder) I've had 4 miscarriages, two with my current DH, and two in my previous marriage. Unfortunately, I am the common factor here! *3/2012: Clomid CD 4-9, awaiting ovulation!! *1-23-2012 BFP! Unfortunately without Progesterone supplements early on, M/C 1-30-2012 *3-2010 BFP! Low progesterone, small gest sac, m/c 4-2010 at 9 wks *9-2008 BFP, Tried Myofacial Release Therapy and Daily Progesterone Injections. m/c 10-2008 at 9 wks *9-2007 BFP, Clomid, Estrace, Gonal F injection, Progesterone suppositories. m/c 10-2007 at 7wks
  • imageYankeeNavyWife:

    Yep... Clomid was a big old joke for me. Might as well have eaten a packet of tic-tacs.  I was even on the highest dose that they give and NADA.

    My RE decided to try the drug Femara and it grew one little 22mm follicle. Our IUI wasn't successful, but I DID ovulate the one cycle we used it for. We just started another cycle a few days ago, and we'll try the Femara again.

    I see that you're military as well. My hubs is AD Navy right now and I know exactly how much it blows to have to do so many steps of this process A.L.O.N.E.

    Let me know if you need to vent about all things Tricare... cause IF isn't enough of a challenge   :0)

    LOL - maybe we should just try tic-tacs instead!! ;) 

    Yep - I'm an Army wife! It sucks when he has training and can't go with me, or when he's been out in the field all day (like this week) and we need to be doing the deed, and he doesn't feel up to it. (no pun intended hehe) *sigh*

    I will have to check into the Femara if this cycle doesn't work out. Good luck to you!!! And same here - if you need to vent!!  Some days it's like "Oh you have too much on your plate... well get a bigger plate!"  Argh!

    Me: 32 DH: 38 TTC for 4 years (total) Me: PCOS, Low Progesterone, Factor V Leiden Thrombophillia (fancy for genetic blood clotting disorder) I've had 4 miscarriages, two with my current DH, and two in my previous marriage. Unfortunately, I am the common factor here! *3/2012: Clomid CD 4-9, awaiting ovulation!! *1-23-2012 BFP! Unfortunately without Progesterone supplements early on, M/C 1-30-2012 *3-2010 BFP! Low progesterone, small gest sac, m/c 4-2010 at 9 wks *9-2008 BFP, Tried Myofacial Release Therapy and Daily Progesterone Injections. m/c 10-2008 at 9 wks *9-2007 BFP, Clomid, Estrace, Gonal F injection, Progesterone suppositories. m/c 10-2007 at 7wks
  • imageBeeBee08:

    I'm sorry you're having trouble with clomid.  It's definitely not for everyone so your increased dose next month might give you the results you're looking for. 

    I just wanted to say that you shouldn't stress about your stress.  The stress you described is not anything that should affect your fertility or follicle growth rate/ovulation.  You're doing fine, you just might need to try a few different meds.

    Good Luck!

    Thanks so much for the encouragement! I try not to stress... this week has been much better! Fingers crossed we won't have to keep doing all this for much longer.. Good luck to you as well! :)

    Me: 32 DH: 38 TTC for 4 years (total) Me: PCOS, Low Progesterone, Factor V Leiden Thrombophillia (fancy for genetic blood clotting disorder) I've had 4 miscarriages, two with my current DH, and two in my previous marriage. Unfortunately, I am the common factor here! *3/2012: Clomid CD 4-9, awaiting ovulation!! *1-23-2012 BFP! Unfortunately without Progesterone supplements early on, M/C 1-30-2012 *3-2010 BFP! Low progesterone, small gest sac, m/c 4-2010 at 9 wks *9-2008 BFP, Tried Myofacial Release Therapy and Daily Progesterone Injections. m/c 10-2008 at 9 wks *9-2007 BFP, Clomid, Estrace, Gonal F injection, Progesterone suppositories. m/c 10-2007 at 7wks
  • imagekflynn81:
    Same thing happened to me. I had lots of follicles but all under 10 that never progressed. Finally by cd16, my RE decided it was a lost cause. She immediately switched me to injections though, and they've worked really well for me!! Good luck!!

    Bummer! What is up with our slow eggs!?? I am surprised your RE gave up on CD 16 - some ppl, like myself, ovulate late!  But at least the injections are working!! YAY!  

    I see you have Factor V as well - do you have the heterozygous or homozygous? Mine is heterozygous, so it isn't as severe, but I'll still have to do Lovenox when I get pregnant. Do they have you on it all the time? I just take baby aspirin until we are preggo, then will do the Lovenox. I'm pretty nervous about it though... but gotta do what we gotta do! 

    Me: 32 DH: 38 TTC for 4 years (total) Me: PCOS, Low Progesterone, Factor V Leiden Thrombophillia (fancy for genetic blood clotting disorder) I've had 4 miscarriages, two with my current DH, and two in my previous marriage. Unfortunately, I am the common factor here! *3/2012: Clomid CD 4-9, awaiting ovulation!! *1-23-2012 BFP! Unfortunately without Progesterone supplements early on, M/C 1-30-2012 *3-2010 BFP! Low progesterone, small gest sac, m/c 4-2010 at 9 wks *9-2008 BFP, Tried Myofacial Release Therapy and Daily Progesterone Injections. m/c 10-2008 at 9 wks *9-2007 BFP, Clomid, Estrace, Gonal F injection, Progesterone suppositories. m/c 10-2007 at 7wks
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