Dbert pretty much summed it up for me. I did start taking it the cycle I got pg. I don't know if it actually helped or if I was just having wacky cycles for the 5 mo before and the cycle I got pg it just went back to normal but my OB said it didn't hurt to take it. I was scheduled to go in and talk more with my OB about my weird cycles the Monday after I found out I was pg so I didn't go in. I did keep taking B6 for about a few weeks after. The nurse had said it was fine to keep taking and would help with m/s if I got it but she never indicated I should not keep taking it (i.e. because of m/c concerns).