My husband and I missed a few season (i think the first 4 seasons!) of 24...and enjoyed watching those on DVD....actually maybe it's a bad recommendation...it was soooo addicting that we would stay up waaaaay past our bedtime....we couldn't turn the TV off!!
For comedies, I suggest 30 Rock and Arrested Development. For dramas, since you like Lost, I suggest Heroes and Alias (but only the first couple of seasons!). House is also good, if you feel in the mood for medical stuff.
Re: TV shows that are worth watching?
Frasier and Friends! I love both!!!
It's Always Sunny in Philadelphia (hilarious)
Mad Men?