TTC after 35

clomid challenge - anyone?

Has anyone done the Clomid challenge before? I am a little nervous. The RE wants to do this as a beginning step to measure my FSH and response to the drugs (I guess?). She also says that it should assist the whole ovulation process. I ovulate on my own, but she said this might help the luteal phase as well.  

She said to call if I experience vision problems. Has anyone had anything out of the ordinary happen with clomid? 

ttc since 2/2010 ~
me (36): Hypothyroid (on Levothroid), low vit. d, borderline/high fsh (day 3: between 7-10) (day 10: 13 during CCCT), AFC: 14
dh (31): awesome (minus one sample with agglutination)
Diagnosis:possible DOR and/or unexplained + elevated NK cells + MTHFR (C677T - one copy)

MAY 2011 - FEB 2012 - 3 injectable IUI's with numerous cancellations due to high TSH levels
MAY 2012 - onto IVF/ICSI (Antagonist Protocol) on BCP and Folgard (3 week delay - cyst - boooo) 5/21 start stims 5/30 ER 11R 8M 3F 6/2 3DT of 3 6/12 Beta #1 83 | 6/14 Beta #2 196 | 6/21 Beta #3 3818 | 6/28 Beta #4 22,213 | 7/2 1st U/S - 2 on board! 8/24 CVS reveals that we have a boy AND a girl on board!

Healthy baby boy and girl born in February, 2013 at 38 weeks and 2 days!


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Re: clomid challenge - anyone?

  • I never did the Clomid challenge, but I've been taking Clomid with my IUI's (I ovulate fine, it's standard treatment for unexplained IF--increase the number of eggs with each cycle and hope one does what it is supposed to). I don't really have any physical side effects from Clomid. I do have some trouble concentrating, and have had three really good screaming matches with DH for no good reason other than he annoyed me. I blame the Clomid for that.

    It didn't do a thing for my LP, despite the fact that I had 2 follies with the first round, and 4 with the second.  

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    TTC #1 since 2009 with unexplained infertility
    IUI#1-4 Jan.-Apr. 2011 = BFNs
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    Beta #1 = 153, Beta #2 = 269, Beta #3 = 675
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  • imagetst1998:

     I do have some trouble concentrating, and have had three really good screaming matches with DH for no good reason other than he annoyed me. I blame the Clomid for that.

     

    Thanks for the warning!  I'll be sure and tell my S/O that I may become somewhat *itchy.  He'll be glad to know - he already likes to track my cycles to better understand my mood swings.

    ttc since 2/2010 ~
    me (36): Hypothyroid (on Levothroid), low vit. d, borderline/high fsh (day 3: between 7-10) (day 10: 13 during CCCT), AFC: 14
    dh (31): awesome (minus one sample with agglutination)
    Diagnosis:possible DOR and/or unexplained + elevated NK cells + MTHFR (C677T - one copy)

    MAY 2011 - FEB 2012 - 3 injectable IUI's with numerous cancellations due to high TSH levels
    MAY 2012 - onto IVF/ICSI (Antagonist Protocol) on BCP and Folgard (3 week delay - cyst - boooo) 5/21 start stims 5/30 ER 11R 8M 3F 6/2 3DT of 3 6/12 Beta #1 83 | 6/14 Beta #2 196 | 6/21 Beta #3 3818 | 6/28 Beta #4 22,213 | 7/2 1st U/S - 2 on board! 8/24 CVS reveals that we have a boy AND a girl on board!

    Healthy baby boy and girl born in February, 2013 at 38 weeks and 2 days!


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  • I never did the clomid challenge. My understanding was that the clomid challenge was more of a "antiquated" test that isn't necessary now.  AMH is a newer test that measures ovarian reserve so you wouldn't really learn anything new by doing the clomid challenge. What was your FSH and estrogen on CD3? Why does your doc want to do to CC?

    I took clomid for 1 cycle. I really hated it.  I had ridiculous hot flashes for 3 weeks. After experiencing that I have a whole new respect for any woman in menopause!

    ETA: just saw your FSH in your siggy. Was your AMH tested??

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

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  • Thanks for the info. I didn't do an AMH yet, but I will ask her about that soon. Hmmm...

    FSH was btwn. 8.4-10.2. Estradiol <50

    She expressed some concern for the FSH, but did an Antral Follicle Count today that was normal.

    I am not exactly sure why she wants to do the Clomid, but she did express that it might help with my overall cycle problems. 

    If I don't like it I will definitely express this. Hot flashes - that's ridiculous.

    Thanks again for passing along info. 

     

    ttc since 2/2010 ~
    me (36): Hypothyroid (on Levothroid), low vit. d, borderline/high fsh (day 3: between 7-10) (day 10: 13 during CCCT), AFC: 14
    dh (31): awesome (minus one sample with agglutination)
    Diagnosis:possible DOR and/or unexplained + elevated NK cells + MTHFR (C677T - one copy)

    MAY 2011 - FEB 2012 - 3 injectable IUI's with numerous cancellations due to high TSH levels
    MAY 2012 - onto IVF/ICSI (Antagonist Protocol) on BCP and Folgard (3 week delay - cyst - boooo) 5/21 start stims 5/30 ER 11R 8M 3F 6/2 3DT of 3 6/12 Beta #1 83 | 6/14 Beta #2 196 | 6/21 Beta #3 3818 | 6/28 Beta #4 22,213 | 7/2 1st U/S - 2 on board! 8/24 CVS reveals that we have a boy AND a girl on board!

    Healthy baby boy and girl born in February, 2013 at 38 weeks and 2 days!


    AlternaTickers - Cool, free Web tickers
  • I took Clomid for 5 cycles. The only s/e I had was being really thirsty. Then on round 5 I got really emotional.  I was sad, it was a horrible feeling. I ovulate on my own as well. Just make sure the RE monitors you closely with u/s.
    Baby Birthday Ticker Ticker Daisypath Anniversary tickers daisypath PitaPata Dog tickers PitaPata Dog tickers Unexplained infertility HSG-clear, DH SA-Great 3 cycles Clomid TI with OB/GYN Switched to RE Jan2011 Feb2011 100mg Clomid + trigger + #1 IUI=BFN Mar. 12,2011 100mg Clomid + Estradiol + #2 IUI BFP 3/20/11, Beta #1 12dpiui 174, Beta #2 17dpiui 1660, Beta #3 21dpiui 6687 image
  • They didn't have me do a Clomid challenge.  Ditto those that have had hot flashes on Clomid.  I have pretty mild ones (maybe 2-3/Clomid cycle), but they will get your attention if they happen.  My luteal phase does seem a bit better - no spotting and is now a more "normal" 14 days instead of 11-12.
    Me: 41, DH 43 TTC #1 since 8/09 CP 10/09.
    3/11 Clomid-Ovidrel-IUI #1-progesterone= BFN.
    5/11 Femara-Bravelle-Ovidrel-IUI#2-progesterone=BFN.
    6/11 Femara-Ovidrel-IUI#3-progesterone=BFP!
    Beta #1 7/1: 39. Beta #2 7/5: 301 U/S 7/19 - saw HB!!
    EDD 3/12/12
    DD born 3/5/12
    Baby #2 Beta #1 12/16: 439.  Beta #2 12/18: 1240
    EDD 8/22/15


  • Initally with the  OB -he perscribed Clomid for three cycles and then an additional 1. After the wasted year I got a refferal to the RE he did testing and had me do the Clomid challenge....He said it was because He could trust his own results and not other Dr's. I really questioned this additional Clomid use however He is the professional so I did it.

    I didn't mind the Clomid, but had lots of hotflashes and night sweats.

    TTC since 2009 very frustrated 42yr and DH 40

    5 cycles of Clomid with satisfactory response=BFN's
    Fibroid removal Nov2010
    IUI Clomid #1 Feb 2011...BFN..damn it!
    IUI Inject's #2 Apr 2011...CANCELLED...low estradiol
    IUI Inject's #3 June 2011...BFN
    IUI Inject's #4 Sept2011...BFFN
    Lap Dec 2011...severe endo..cyst removed..some remains...
    IVF#1 Apr 2012 ....cancelled due to over suppression
    IVF#2 July 2012....6 follies...only 1 retrieved....BFFN
    surgery suggested to move ovary to an better placement but....we moved two time zones away and are financially and emotionally empty

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