Hi there... re-intro and ?

thamesie

Not sure if anyone will rec me... but I was a frequent poster about a year ago, before the TTCAL board split. I had a 2nd miscarriage in Feb. Since then, I have been seeing an RE and have had surgery to resect my uterine septum... twice! Not going to bore you with the details... just not fun! I also found out, from the very expensive blood work that I had done ::rolls eyes::, that I have one copy of the MTHFR mutation. I am currently taking 3000 mcg a day... but was wondering if any of you who may have the same gene are taking more. JW and TIA!

michrocc

Welcome back! I do remember you! I don't have an answer, but I'm sure someone else will... All the best, though!

shanna82

I have hetero C677t MTHFR and I take 4mg FA, BA, B6, and B12 plus a PNV.  The baby aspirin is for the possible blood clotting from the mutation, and the B vitamins are supposed to help with the absorption on FA--the other possible problem.

2 OBs I've had have told me that it probably has nothing to do with my losses.

Welcome back.

 

rjl07

Welcome back - I remember you!  I don't know the answer to your question, but I hope that the extra FA helps you.

butterfly843

Welcome back!

dondraandluis

I remember you! Welcome back! I also had a uterine septum removed and have the same MTHFR as Shanna. I take 2 mg of folic acid  on top of my pnv (not sure how many mcg that is) and baby aspirin. I will also have to do Lovenox injections when pg.

ColleenS629

Welcome back!

tlcW0714

I have one copy of MTHFR, I take 4000 a day and once I am pregnant I will take baby asprin daily. 

mdm2137

Welcome back!

triple_sevens

Hi thamesie, I remember you.

I also have one copy of MTHFR. My RE doesn't believe it has anything to do with my losses. She said it's a very common mutation. I'm not taking anything for it other than my regular prescription prenatal. I don't believe we will be changing anything once I get pregnant again, either, whenever that is.

Susan Whelan

Hi, I work for Neevo. Maybe I can give you some additional information about MTHFR? As you know, MTHFR is a genetic classification, referring to how much of the MTHFR enzyme is present in your body. Having MTHFR is an indication that you may be limited in the value you get from folic acid. You should seek additional folate support from diet and/or a more modern source of supplementation, such as L-methylfolate or metafolin. Modern prenatal vitamins have begun to include L-methylfolate to help patients with MTHFR.

As for the different classifications of MTHFR, homozygous MTHFR is either CC or TT. Approximately 50% of the population is CC which is considered normal. These people have an ample amount of MTHFR enzyme and can easily process folic acid into L-methylfolate. Only about 10% of the population is TT. These people have less than 30% of the normal amount of MTHFR enzyme. These individuals are at risk for adequate folate status. The rest of the population are heterozygous or CT, like yourself. They have between 30% and 70% of the normal MTHFR enzyme level, and their ability to process folic acid falls somewhere between the groups listed above.

I hope this information on MTHFR helps. I wish you luck.