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Progesterone In Oil ? for IVF Ladies

mdluv21mdluv21
in Infertility

This is the only IVF med I haven't already purchased...do  you guys remommend the seaseme seed oil or the ethyl oleate?

They said over the phone that the ethyl oleate is a little thinner so I am thinking that is a good thing?  It is $10 more a vial but if it hurts less or has less side effects I will buy that one.

TIA!

TTC since 07/2009
Me: PCOS, Blood/Immune Issues DH: Low all 3
Jun.- Sep. 2010 IUI#1-#3 = BFN
Oct. 2010 = IVF #1 = B/G Twins (passed away Feb. 2011)
May 2011 = Myomectomy and trans-abdominal cerclage (TAC)
Sep. 2011 = Surprise BFP = C/P
Feb. 2012 = sFET #1 = BFN
Feb.2012 = Hail Mary IUI #4 = BFN
April/May 2012 = FET #2 w/our last two embies = BFP (Please let this be it!)
Beta #1 8dp5/6dt = 234 Beta #2 10dp5/6dt = 695 Beta #3 12dp5/6dt = 1796 Beta #4 17dp5/6dt = 17,888 U/S #1 May 17, 2012 = Twins
Baby B's heart stop beating at 9 weeks 5 days
Our little miracle baby is a boy. :)

Baby Boy Owen and Baby Girl Avery were born too early on Feb. 13, 2011 due to a pedunculated fibroid, incompetent cervix and suspected placental abruption.
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"What the heart has once owned and had, it shall never lose." - Henry Ward Beecher
SAIF/PAIF Welcome
Lots of love and luck to my PAIF/3T/IF Veteran ladies, especially my dear friend Zookie. Congrats to Papps, Teach84 and Starbuck on their little ones.
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Re: Progesterone In Oil ? for IVF Ladies

  • Yellow_DaisyYellow_Daisy
    My doc ordered the ethyl oleate for me.  I am taking my first shot tonight, eek!
    TTC since 8/2004
    Me - DX Hashimoto's Disease, Hypothyroid, Rheumatoid Arthritis
    DH - DX Azoospermia - Sertoli Cell Syndrome
    DS-IUI #1-4 BFN IVF #1 - BFP! It's a boy!!!
    Baby Birthday Ticker Ticker
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  • BigHairQueenBigHairQueen member
    I have been on both. I got a rash with ethyl oleate on my last FET and my RE thought I might have had a reaction to the carrier, so she switched me to seaseme oil. I didn't  get a rash this hit but I did notice the my butt was more sore this time than the previous 2 cycles. GL!
    Stacy
    PCOS, RPL, & Anti Cardiolipin Antibody
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  • LnR70707LnR70707 member
    I have the sesame oil because insurance doesn't cover the ethyl oleate, I did my first injection tonight and so far it isn't even sore.  I did heat before and after.


    imageimage
    2 years, 2 surgeries, 2 clomid fails, 2 IUIs, 1 loss, IVF #1 - 10/25/10 = BFP!, DS is now 3.5yrs!
    TTC #2 - 6/12 surgery #3, FET #1 & 1.2 = BFN, 12/2012 FET #2 = BFP! DD is 1.5 yrs!
    Surprise! 12/16/14 BFP, loss #2 12/31/14

    I can't wait for the "im getting a divorce" post in 5 years or so because your husbands were fed up with your disgusting chair asses from playing on the knot all day and getting fired 4-5 times for not doing any work. you guys are all winners!! ~ Laur929

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  • thewormstheworms member

    i use ethyl oleate and have had allergic reaction to sesame oil.  ehtyl oleate is thinner than sesame oil and you can use a thinner needle to inject it.

    gl

    image
    Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
    Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)

    It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
    MTHFR A1298C & C677T, Immune Issues and Factor II
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  • KelinandKevinKelinandKevin member
    I used the sesame seed oil with my IVF and broke out in a horrible rash with welts about 2 weeks into it.  For my FET this month I am going to try cotton seed oil. 
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  • Yellow_DaisyYellow_Daisy
    imagetheworms:

    i use ethyl oleate and have had allergic reaction to sesame oil.  ehtyl oleate is thinner than sesame oil and you can use a thinner needle to inject it.

    gl

    Oh yes I forgot the skinny needle part.  I am using the same needles as I did for the menopur IM shots.  A big one to draw it up and the thinner one to do the shot.

    TTC since 8/2004
    Me - DX Hashimoto's Disease, Hypothyroid, Rheumatoid Arthritis
    DH - DX Azoospermia - Sertoli Cell Syndrome
    DS-IUI #1-4 BFN IVF #1 - BFP! It's a boy!!!
    Baby Birthday Ticker Ticker
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  • robynssrobynss
    I have sesame oil... I dont think there is a problem at all! I just like to ice first because although I cant see the injwctiin going in i am still intimidated by the size of the needle. I dont feel a think except sore butt cheeck muscles the next day!!! Sorry if this is TMI!
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  • GenRN45GenRN45

    i recommend neither.

    I recommend Olive Oil. It's not as thin as ethyl oleate, but IMO is a much more gentle oil, and i've never heard of anyone have a reaction to it. Reactions to sesame are EXTREMELY common, and i've heard of people reacting to the ethyl oleate as well.

    Good luck.

    Dx: MFI, DOR, 9 Fibroids and homozygous MTHFR

    Baby Birthday Ticker Ticker

    "Smudge's Story - How to Grow a Dandelion" will return soon!
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    "If dandelions were hard to grow, they would be most welcome on any lawn."

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  • STL34STL34 member
    I believe mine was in castor oil.  So, I don't have any recommendations for you. Good luck!

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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  • mdluv21mdluv21
    imageGenRN45:

    i recommend neither.

    I recommend Olive Oil. It's not as thin as ethyl oleate, but IMO is a much more gentle oil, and i've never heard of anyone have a reaction to it. Reactions to sesame are EXTREMELY common, and i've heard of people reacting to the ethyl oleate as well.

    Good luck.

    I wasn't given that option.  Sad

    TTC since 07/2009
    Me: PCOS, Blood/Immune Issues DH: Low all 3
    Jun.- Sep. 2010 IUI#1-#3 = BFN
    Oct. 2010 = IVF #1 = B/G Twins (passed away Feb. 2011)
    May 2011 = Myomectomy and trans-abdominal cerclage (TAC)
    Sep. 2011 = Surprise BFP = C/P
    Feb. 2012 = sFET #1 = BFN
    Feb.2012 = Hail Mary IUI #4 = BFN
    April/May 2012 = FET #2 w/our last two embies = BFP (Please let this be it!)
    Beta #1 8dp5/6dt = 234 Beta #2 10dp5/6dt = 695 Beta #3 12dp5/6dt = 1796 Beta #4 17dp5/6dt = 17,888 U/S #1 May 17, 2012 = Twins
    Baby B's heart stop beating at 9 weeks 5 days
    Our little miracle baby is a boy. :)

    Baby Boy Owen and Baby Girl Avery were born too early on Feb. 13, 2011 due to a pedunculated fibroid, incompetent cervix and suspected placental abruption.
    Lilypie Angel and Memorial tickers

    "What the heart has once owned and had, it shall never lose." - Henry Ward Beecher
    SAIF/PAIF Welcome
    Lots of love and luck to my PAIF/3T/IF Veteran ladies, especially my dear friend Zookie. Congrats to Papps, Teach84 and Starbuck on their little ones.
    Report Reply
  • schoolsoutbrideschoolsoutbride
    Supposedly the ethyl oleate works better because it's thinner and leaves more of a bump.  That stuff BURNED, though and made me sore all day.  I switched to Sesame Oil and had no problems.  I think try one and if it bothers you switch it up.  I was also fine with cottonseed oil, which is a little thinner than sesame oil.
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  • GenRN45GenRN45
    imagemdluv21:
    imageGenRN45:

    i recommend neither.

    I recommend Olive Oil. It's not as thin as ethyl oleate, but IMO is a much more gentle oil, and i've never heard of anyone have a reaction to it. Reactions to sesame are EXTREMELY common, and i've heard of people reacting to the ethyl oleate as well.

    Good luck.

    I wasn't given that option.  Sad

    Neither was I. I had to request it.
    Dx: MFI, DOR, 9 Fibroids and homozygous MTHFR

    Baby Birthday Ticker Ticker

    "Smudge's Story - How to Grow a Dandelion" will return soon!
    The Dandelion Archive
    "If dandelions were hard to grow, they would be most welcome on any lawn."

    We're Finally Three Image and video hosting by TinyPic
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  • MrsRumpfMrsRumpf
    Not sure what oil I have but THE THINNER THE BETTER.  Sore "keaster" (sp?) over here!
    My Story and Blog:
    The Conception Craze

    1/2009- TTTC
    After 7 rounds of clomid and HcG, Three failed IUI's with an ectopic pregnancy, two shots of methotrextate, ER visits, breaks, low (3%) morphology One IVF cycle (lupron, gonal-F) that ended in another ectopic, more methotrexate, A Lap to disconnect both tubes, remove endo and a hydrosalphinx, . . .we are finally expecting TWINS from FET#1!
    1.11. 2011: Beginning FET cycle!
    3.11.11- FET! (DH's birthday!) 2 blasts transfered!
    3.20.11- BETA #1 BFP!!! 272! (9dp5dt)
    3.23.11- BETA #2 1346!!! (12dp5dt)
    4.8.11- U/S #1. . TWINS!!! . . .TWO BOYS!
    9.10.11-My beautiful Boys arrive unexpectedly at 28 weeks, 6 days. imageimage
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  • Yellow_DaisyYellow_Daisy

    I did my first PIO in ethyl oleate tonight and it wasn't any different from the IM menopur except that it didn't burn like the menopur did.  I found it to be a very easy shot, no pain at all.  I put the bottle of PIO in my bra (saw that tip on here) for 10 min to get it warm and then drew it up with the big needle, switched to the small needle and then DH did the shot.  After the shot I massaged the area for a couple minutes and then put a hitting pad on it.  The oil appears to have absorbed fine and I don't have a lump.

    Also I didn't have any pain or soreness from the IM shots I have been doing daily while stimming.  I don't know if that will change with the thicker oil shot, but I will let you know.

    TTC since 8/2004
    Me - DX Hashimoto's Disease, Hypothyroid, Rheumatoid Arthritis
    DH - DX Azoospermia - Sertoli Cell Syndrome
    DS-IUI #1-4 BFN IVF #1 - BFP! It's a boy!!!
    Baby Birthday Ticker Ticker
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  • njohnson1972njohnson1972 member
    Also, I would check to see if you insurance covers it.  I don't have insurance coverage for my IVF meds, but they do cover PIO.  PIO is used to maintain pregnancy, so they cover that.
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  • eshellwigeshellwig member
    I just took my first progesterone shot and although it didn't hurt when dh gave it to me, but half hour later I feel so sore! How long does it last? Lilypie Assisted Conception tickers
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  • pblgepblge member
    @eshellwig - Please don't revive old ("zombie") threads like this! No one wants to see the tickers. There are multiple PIO threads on page 1 of the main board right now.
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
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    image
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  • eshellwigeshellwig member
    Oh I didn't know.
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