Anyone else have their LO start with massive quantity and increased frequency spit-up on nystatin? My DD#1 had reflux and so far DD#2 has spit-up infrequently and rarely in large quantities. She is 3 weeks 5 days old and today has spit-up 4 massive quantities and at each of her last 4 feedings. This is unusual for her and she now seems uncomfortable/fussy which is also unusual for her. She started nystatin on Thursday and that may be the cause but I am concerned about reflux since this is the time it starts. Just curious if anyone had a problem with LOTS of spit-up while LO was on Nystatin?Obviously it isn't an urgent problem, but my DH is worried about it, too. We had such a hard time with DD#1 until we got the reflux under control.