Infertility

At What Size Is A Follie Too Mature?

I just realized, when my one lonely follie was 19mm, my RE told me to do another night of stims, then trigger the night after that, then I probably O'ed 36 hours later.  Meaning that the time between when it was 19mm and when I O'ed was about 72 hours.  So going by the 1-2mm per day growth, that would make it 22mm-25mm.  Would the 25mm be too big?

 

TTC in 2008. Stage II/III endo, Hashimotos hypothyroid, low morph (3%).
2 cycles Clomid/Ovidrel/TI/Crinone=BFN.
IUI #1 - 4 Follistim/Ovidrel/IUI/Crinone = BFN.
IVF #1 - Antagonist w/ ICSI 4/10. 17 retrieved, 5DT of 2, BFN :(
IVF #2 - Long Lupron w/ ICSI 6/10. 15 retrieved, 3DT of 2, BFFN!!
Lap 7/21/10
IVF #3 - Clomid/Antagonist w/ ICSI 10/10. 14 retreived, 3DT of 3, BFP 10/20 but m/c. No HB 11/15/10 - D&C 11/17/10.
FET - 2 blasts, 1 survived the thaw. Transfer 2/19. Beta #1 3/1 375, Beta #2 3/3 885, Beta #3 3/8 4261, Beta #4 3/11 9005. U/S 3/8 1 sac 1 yolk, U/S 3/16 1 heartbeat 114bpm!

 

James born Oct. 24th 2011 via c-section at 38 weeks!

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Surprise BFP - Jack born April 28, 2013 via VBAC after PTL at 33 1/2 weeks!

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Re: At What Size Is A Follie Too Mature?

  • My largest follie this time was 23mm on the morning of trigger day.  We still got a mature egg from it.  I think around 27-28 is when they start getting too big.
    TTC #1 since 6/07, Dx = Ovulatory dysfunction, DOR, and autoimmune issues ~ 4 Clomid cycles, 1 Femara Cycle, 6 Injectible IUI cycles~ 4 Chemical PG's ~ IVF #1 Dec '09 = BFP!! Beta 8dp3dt = 68 10dp3dt = 276 16dp3dt = 1511 ~ First U/S 1/14 = 3 Heartbeats!!! Lost Baby C at 8w5d Emergency Cerclage at 22wks saved our babies lives Lilypie Second Birthday tickers
  • hmm - if my follie was 18 or 19, they would have me trigger the next night...but i think it ok - some wait until the follie is 22 to trigger

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  • My RE thinks that any thing over 27 might not be the best quality.
  • It depends on the drugs you're using to stim with:

     

    Q: At what size are follicles considered mature?

    A: Many doctors monitor follicle development during IUI cycles. Most trigger when the dominant follicle is within a certain size range. While there is always some difference in doctor preference, the norms are unmedicated 20-24mm, clomiphene citrate 20-24mm, FSH-only meds 17 or 18mm minimum, and FSH+LH would be 16 or 17mm minimum. It is possible for slightly smaller follicles, 14-15mm, to contain a viable egg. Also, follicles continue to grow until they release, usually at a rate of about 1-2 mm per day. A woman may ovulate more than one follicle in a cycle, but the releases will occur within 24 hours. When hCG is not used, only follicles close in size are likely to release. The use of hCG induces ovulation in about 95 percent of women, and will get most mature follicles to rupture.

     

     

    I know my RE discounted my 26 as a non-player while trying to get 3 more that were smaller to group up.  

    But... how have you been stimming?  And what doses are you on?

    What's your E2 (if you know it?)

    Chances are he's expecting you to fall on the lower growth side based on how he's seen your cycle progress so far.

    That would put you at the perfect size!

     


    Our IF journey: 1 m/c, 1 IVF with only 3 eggs retrieved yielding Dylan and a lost twin, 1 shocker unmedicated BFP resulting in Jace, 3 more unmedicated pregnancies ending in more losses.
    Total score: 6 pregnancies, 5 losses, 2 amazing blessings that I'm thankful for every single day.
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