I see some that frequent my blog have already read and commented (thanks!) on this. I had b/w done last Monday for several blood cloting disorders and antibodies. Same as with my lap & hys, I had no indication I actually had these, but had the time before starting IVF # 1 in May to get it done. Most b/w is randomly covered by my insurance if sent to an outside lab so I figured why not.
Well Friday I was told I have MTHFR...and no I didn't just swear at you...it's a gene defect that basically means your blood clots too good. I had to wait until today after my doctor reviewed it to find out what exactly that meant. The only reliable information I found on the internet I copied onto my blog if you're interested (link's in my siggie!).
In a nutshell, basically MTHFR causes tubal defects (i.e. spinal Bifida) and miscarriage if left untreated. I am now required to take a low dose aspirin every day (for blood thinning) along with a B Complex vitamin (for extra B6, B12, and folic acid) and a prescription prenatal since that's the only way I can get a full mg of folic acid which is now what I need.
Not the best news in the world, but feel so blessed that we know before IVF #1. I felt like I had to share it with you all. Whether you've had loses or not, I think it's a quick and easy test to have done. I hope this knowledge helps some one here.
Re: Turns out I'm not 'totally' unexplained afterall (SAIFW)
Because we're fancy like that.
My cycle buddy! So happy that they found something wrong with you! (isnt that sad when we are happy that they actually find something)
I have MTHFR too! I take Metnex and the baby asprin daily- I was also told that I will need to be on lovemex after pregnancy is achieved.
Did you request the testing or did your RE?
Do you know what all they tested for?
Sara-HUGE deal to know this now. You will be just fine and I am so glad you got this info now.
I also had a bunch of this b/w done after my loss just to know. Gor forbid any more losses happened that could have been prevented.
I'm so glad you got the info before IVF.
GL!!
Worrying does not empty tomorrow of its troubles, It empties today of its strength. ~Corrie ten Boom
Courage doesn't always roar. Sometimes courage is the little voice at the end of the day that says I'll try again tomorrow. ~Mary Anne Radmacher (thank you beadinglady)
It's been a long journey. TTC since 9/06. multiple IUI's and IVF's and 4 m/c's. IVF#3 = BFP, twins, induced at 34w6d due to baby b passing away (no explanation). Delivered on 35w1d, Baby A - baby girl, and Baby B - baby boy, our little angel.
MTHFR A1298C & C677T, Immune Issues and Factor II
I saw this on your blog and I'm sorry you have that, but glad they found it before your IVF. Hopefully treating your beforehand will ensure a healthy pregnancy. GL!
I wonder if I'll get that test?
PCOS, Ectopic & M/C of twins October 2010, Currently TTC #2
Jaime & Brent
Oahu, Hawaii | Sept. 9, 2005
My Food Blog - Good Eats 'n Sweet Treats
It's a nice feeling to at least find something. I have MTHFR (C677t) & FVL (hetero for both). Do you know if you have 1 gene or 2? 1 is considered not a huge deal but you are definitely on the correct treatment. The most concern with the MTHFR is that it affects the body's ability to absorb folic acid. Folic plays a large part in the development of a healthy placenta. I take 4mg of Folic Acid in addition to what is in my prenatal, BA, and this cycle, we will start the lovenox at 3dp trigger instead of after a + pg test. Crazy as it is, most of the population probably has MTHFR (1 copy) (and FVL as well).
GL with your IVF!
i am so glad you got some answers. Must feel good in that respect, and knowing you are fully prepped now.
Good luck with your cycle!
I have 2 mutations, one hetro and one homo. And the homo one I have is 1298c. They said the C677t was the "more serious" one and would probably require lovenox. I would have totally taken that if necessary and again was so thankful to find it out before IVF #1. Not that nearly 2 years of TTC wasn't bad enough, but basically assuming IVF completely OOP was bound to fail would really suck! Good luck in your upcoming cycle too!
Its not great news by any means but I agree that at least there is something "fixable".
I too have MTHFR and Factor V. I do the same protocal as you and meet with my RE this week to decide the lovenox. I am 4weeks 3 days along.
GL with IVF!
~Working Mom~Breastfeeding Mom~Cloth Diapering Mom~BLW Mom~
Blog - No Longer on the DL ~ The Man Cave
Shawn and Larissa
LO #1 - Took 2 years and 2 IVFs ~ DX - severe MFI mild PCOS homozygous MTHFR (a1298c)
LO #2 - TTC 7 months, surprise spontaneous BFP!
Ok as much as it isn't awesome news, it is good to know that you "know "something about yourself and you are right---before you go into IVF#1!!
Oh sara best of luck to you!!