Nationwide PIO shortage? — The Bump

Nationwide PIO shortage?

Anyone else coming up against this? My out of pocket maximum was met many months ago and although we aren't starting another FET cycle until the new year, I wanted to get my meds ordered and lined up while they cost me nothing, and there is STILL, after how many months?, a shortage of PIO. I've heard PIO isn't used as much in Europe/Australia - they use suppositories - but I've been prescribed both the injectible AND the suppositories. GAH, as if this crap isn't hard enough!!

Re: Nationwide PIO shortage?

  • Yeah i am having to pay 50.00 more per vial, and on top of that they recently upped my dosage. I am pretty bitter!

  • @Crystal321 They're charging MORE too?? That feels semi-illegal. Like, paying more isn't going to create more product, so what is the rationale for that?

  • This company makes them on demand and ships overnight. It makes no sense to me tbh

  • I have to have it in ethyl olate (I think this spelling is correct) and it costs like $50 more a vial that just in sesame seed oil. But that's all anyone I call has in stock. 
  • Yes, we are experiencing the PIO shortage here, too. Normally the pharmacy here has everything plus the kitchen sink, but they had to do a referral for me through Freedom. (The lady on the phone said they will probably be the only company to have it until January.) Luckily it was just a $10 co-pay with my insurance, but that's shady that anyone would jack up their prices. I also have the suppositories waiting for me, so I'll be having all sorts of fun with progesterone in the coming days.
    Me: 35 DH: 28
    TTC since June 2016

    Azoospermia diagnosis (zero count) Dec 2016

    AZFc chromosome microdeletion discovery March 2017
    Unsuccessful TESE for DH in August 2017
    October IVF with donor sperm
    29R, 24M, 16F, 2d5, 4d6 (6 embryos total)
    Only 3 could have PGS. 2/3 normal. 5 embies frozen
    12/15/17 FET--CP
    2/7/17 FET #2--BFN
    Chronic endometritis diagnosis May 2018
    ERA Sept 2018--borderline receptive--12 more hours of progesterone
    Abnormal SIS Oct 2018
    Repeat hysteroscopy Nov 1.
    FET ??
    ~*~*~Nevertheless, she persisted~*~*~
  • Yes, I dealt with it today too, I used to deal with Freedom, but my insurance now requires me to go through Caremark for everything normally.  My nurse called me today and said she was going to have to call it into a small pharmacy that she thought might be able to give me a small quantity, and I convinced her to send the script to Freedom since I used them in the past.  I called Freedom and the woman told me "We don't have any, there's a national shortage."  I said "hmm that's weird, my nurse said since I used you in the past you would be able to help me."  She explained they aren't able to fill new prescriptions, only refills on existing prescriptions.  So crazy, she did say they believe the shortage should be ending soon, and I am really keeping my fingers crossed, because I am only getting enough to get me through to beta and I had the ERA so we know that I require 6 days of high dose PIO before FET and then to remain on 2ml daily for awhile.  
  • I ordered some with freedom and will get it tomorrow. Price seemed to stay the same. 
    TTC history in spoiler box:
    Me: 42, single
    Hysteroscopy: 2013
    IUI #1-2: 2013 BFN
    Surgery 10/2015: Planned to start trying again but had a surgery. (Not related to fertility)
    Surgery 5/2016: Planned to start trying again but had another surgery. (Not related to fertility)
    IUI  #3-5 (with Clomid): summer 2016 BFN
    IVF #1: 11/2016. 30R; 21M; 20F; 8B (6 day5 & 2 day6); 4 normal after PGS
    Medicated FET #1: 1/31/2017 transferred 1 embryo 3AA. BFP. Embryo stopped growing at 6w 1d. MUA at 9w 3d.
    Medicated FET #2June 2017 - cancelled...
    Hysteroscopy #2: June 2017
    Medicated FET #2: 8/7/2017 transferred 1 embryo 5BB. BFP. Ended in CP.
    Medicated FET #3: 10/11/2017 transferred 1 embryo 3AA. BFN
    ERA: December 2017 - need an extra 12 hours of PIO
    Medicated FET #4: 1/24/2018 transferred 1 embryo 4AA. BFN
    Out of embryos.  :'(
    IVF #2: 03/2018.

  • My office called the script into Cornerstone in Pennsylvania today. Not sure why they have some and no one else does!

  • Hii All, my RE just ordered the meds for my FET and the specialty pharmacy called me saying there's a PIO shortage. The manufacturer advised that PIO is on backorder until late 2018. I was shocked, to say the least. Thankfully, the insurance company allowed me to find another pharmacy who has it and that they'd approve an override to pay for it. My RE ordered from Cornerstone in Ohio for me. @sarcasticowl my RE said Cornerstone is one of the most frequently restocked mail-order pharmacies. Now seeing that they are in multiple states, they can probably leverage PIO quantities elsewhere to get them out to patients quicker. 

    Me (33) & DH (29)
    DS (13) DS (11)

    TTC#3 since '10 (PCOS)
    2 IUIs 2013 (1 canceled and 1 BFN)
    Ready to try again 2017: 

    IUI converted to IVF Dec'17
    ER 12/11, 20 eggs retrieved/15  mature, 12 eggs fertilized and 5 day5 blasts frozen
    FET set for January 2018

  • Hmm....I am using New Era out of Oregon.  They told me there is a shortage, so I'm only getting 1 vial of PIO sent to me, not the 3 that were prescribed.  They'll send me another vial once I am close to actually needing it.  They have the meds and are just carefully doling them out so more people can get them, rather than a few people having a full supply and a bunch of others being told they get none.
    Me: Age 40  Husband: Age 41
    Chemo killed my ovaries (along with a BRCA1 mutation, which causes DOR)
    4/30/13 ER just prior to chemo: 8 embryos frozen at 2pn. 2 survived to blasts/1 PGS normal

    4/16 ER cancelled on CD7: 1 follicle on L/ 0 follicles on R
    FET #1  7/13/16  BFN

    Super shocker +HPT 9/19
    Baby Alyce arrived 5/8/17

    Went forward with donor eggs from my sister for baby #2
    ER 4/24, 5 eggs fertilized/1 survived to blast and was chromosomally normal.

    FET 2/15 (my sister/donor's birthday!).  Beta 10dp5dt:172; beta 12dp5dt: 425

    My TTC/Cancer/Random thoughts blog:
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