IVF Trigger side effects?? Anyone??? — The Bump
Infertility

IVF Trigger side effects?? Anyone???

Hi Folks,

This is not my first ER (6th in fact) however this is the first time that i'm not feeling so great after taking the trigeer shot.  Noveral 10,000 units.  Could I really be having an allergic reaction to it all of a sudden.  having this strange tightness in my left hand and its very tender in one area, feeling super bruised.  Dr google says its a reaction.  Anyone else experience this?  I'm not one to run to hospitals at all.  How concerned to I need to be??

Any input is appreciated!!


History of TTC in spoiler box
TTC since 2014
Unexplained Infertility - but I am 40...Low AMH .30
7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
IVF#7 June 2017 // EPP praying this is it and then on to an FET!

Re: IVF Trigger side effects?? Anyone???

  • Hi hun sorry your feeling like that. I finished my trigger and the only side effect I had was I was itching around the injection site and a lot of bruising. I used ice before and after and it went away
  • Hi hun sorry your feeling like that. I finished my trigger and the only side effect I had was I was itching around the injection site and a lot of bruising. I used ice before and after and it went away
    thanks for the input!!  The strange thing is I did do it in my butt cheek and my arm and leg are bothering me... hoping this feeling is just temporary!
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • Loading the player...
  • Oh wow. I'm doing the PIO and boy oh boy the actual shot isn't that bad. However, afterwards my legs ache really bad
  • @hopeful_mom I didn't realize you did the trigger in the butt. If that's the case, you probably hit a nerve. Both my upper outer thighs are numb from the PIO injections I've done 5 months ago! It's much better now. But still not 100%. 

    So my guess is that you hit a nerve. The arm and the leg are the same side you did the injection at?
    TTC history in spoiler box:
    Me: 42, single
    Hysteroscopy: 2013
    IUI #1-2: 2013 BFN
    Surgery 10/2015: Planned to start trying again but had a surgery. (Not related to fertility)
    Surgery 5/2016: Planned to start trying again but had another surgery. (Not related to fertility)
    IUI  #3-5 (with Clomid): summer 2016 BFN
    IVF #1: 11/2016. 30R; 21M; 20F; 8B (6 day5 & 2 day6); 4 normal after PGS
    Medicated FET #1: 1/31/2017 transferred 1 embryo 3AA. BFP. Embryo stopped growing at 6w 1d. MUA at 9w 3d.
    Medicated FET #2June 2017 - cancelled...
    Hysteroscopy #2: June 2017
    Medicated FET #2: 8/7/2017 transferred 1 embryo 5BB. BFP. Ended in CP.
    Medicated FET #3: 10/11/2017 transferred 1 embryo 3AA. BFN
    ERA: December 2017 - need an extra 12 hours of PIO
    Medicated FET #4: 1/24/2018 transferred 1 embryo 4AA. BFN
    Out of embryos.  :'(
    IVF #2: 03/2018.

  • prudence9-2 did the injection on the right butt cheek and have the sensations on the left.  I used a 20 gauge instead of 22 I think.  This time they didn't send the needles with the trigger so I used what I had...not sure if thats an issue...even though I didn't see anything.  
    My clinic still hasn't responded which is unlike them.  Just hoping that it starts to go away soon!  I'm more concerned that it shouldn't cause a problem for my ER.  Maybe we did hit a nerve it did hurt this time around too.

    Knottie704b93630c50d2cf yes i hear PIO is not fun that is the one shot I'm nervous about having to take come time for my FET!
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @Hopeful_mom yikes! The 20 gauge is thick!!! And I'm not sure where nerves go. But it might be that nerve on the right butt goes to the left side of the body. Not sure  :s hope they get back to you soon!
    TTC history in spoiler box:
    Me: 42, single
    Hysteroscopy: 2013
    IUI #1-2: 2013 BFN
    Surgery 10/2015: Planned to start trying again but had a surgery. (Not related to fertility)
    Surgery 5/2016: Planned to start trying again but had another surgery. (Not related to fertility)
    IUI  #3-5 (with Clomid): summer 2016 BFN
    IVF #1: 11/2016. 30R; 21M; 20F; 8B (6 day5 & 2 day6); 4 normal after PGS
    Medicated FET #1: 1/31/2017 transferred 1 embryo 3AA. BFP. Embryo stopped growing at 6w 1d. MUA at 9w 3d.
    Medicated FET #2June 2017 - cancelled...
    Hysteroscopy #2: June 2017
    Medicated FET #2: 8/7/2017 transferred 1 embryo 5BB. BFP. Ended in CP.
    Medicated FET #3: 10/11/2017 transferred 1 embryo 3AA. BFN
    ERA: December 2017 - need an extra 12 hours of PIO
    Medicated FET #4: 1/24/2018 transferred 1 embryo 4AA. BFN
    Out of embryos.  :'(
    IVF #2: 03/2018.

  • prudence9-2 nurse never called and the dr did instead and said i should go to the hospital...r they kidding me!!  Maybe its a blood clot and he's just not sure.  UGH!!!  Obviously I have no desire to go...not sure what to do...
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • Blood clots can be fatal...if doctor says go I wouldn't question it!
    ******TW*****
    Me 39 DH44
    Married 8/2/14
    TTC 9/14
    Dx: PCOS, blocked L fallopian tube, suspect poor egg quality
    MFI (low #, poor morphology)
    IVF #1 9/15 Failed
    IVF #2 12/15 Failed
    1st DE FET  5/16-BFN :(
    2nd DE FET 7/18-BFP :)
    8/17 Baby HR 140/min EDD 4/6/17
  • @Hopeful_mom- oh no! If the doctor thinks you should go to the hospital, I think you should just in case! Hope it is nothing. 
    Me: 41  DH: 46
    Unexplained infertility/AMA, polycystic ovaries, insulin resistance
    FET#1(July 2017): eSET of first of 4 PGS-normal embryos, DS born 3/30/2018
    FET#2(Oct/Nov 2019): eSET  
  • @Hopeful_mom did you go to the hospital? What did they say? Hope it's nothing!!
    TTC history in spoiler box:
    Me: 42, single
    Hysteroscopy: 2013
    IUI #1-2: 2013 BFN
    Surgery 10/2015: Planned to start trying again but had a surgery. (Not related to fertility)
    Surgery 5/2016: Planned to start trying again but had another surgery. (Not related to fertility)
    IUI  #3-5 (with Clomid): summer 2016 BFN
    IVF #1: 11/2016. 30R; 21M; 20F; 8B (6 day5 & 2 day6); 4 normal after PGS
    Medicated FET #1: 1/31/2017 transferred 1 embryo 3AA. BFP. Embryo stopped growing at 6w 1d. MUA at 9w 3d.
    Medicated FET #2June 2017 - cancelled...
    Hysteroscopy #2: June 2017
    Medicated FET #2: 8/7/2017 transferred 1 embryo 5BB. BFP. Ended in CP.
    Medicated FET #3: 10/11/2017 transferred 1 embryo 3AA. BFN
    ERA: December 2017 - need an extra 12 hours of PIO
    Medicated FET #4: 1/24/2018 transferred 1 embryo 4AA. BFN
    Out of embryos.  :'(
    IVF #2: 03/2018.

  • Hopeful_momHopeful_mom
    2500 Comments 500 Love Its Third Anniversary Name Dropper
    member
    edited August 2017
    thanks so much for the input ladies - yes I maybe should've gone to the hospital but I did not and thank g-d I'm still here :)  Blood clots can be fatal I just didn't think that was the issue.  My other Dr does believe that I am having an allergic reaction for whatever reason but the fact that its getting better and not worse means I should be fine AND more importantly it should NOT cause an issue for ER tomorrow...and lets be honest thats the main concern here.   :D
     
    Crazy that I've taken this shot 5x already and all good, yet this time there was an issue.  It definitely feels off but at least not as intense as last night and its only in my hand and arm and not my leg.  Always gotta worry about something!
    History of TTC in spoiler box
    TTC since 2014
    Unexplained Infertility - but I am 40...Low AMH .30
    7 - IUI (50mg-150mg Clomid) Feb - August 2016 all BFN 
    IVF#1 August 2016 (Antagonist protocol 4/5 eggs) Cancelled cycle :( RE thought I would get at least 10.
    IVF#2 Sept 2016 (microdose luporn pro - disappearing follies, ONLY ONE, convert to IUI) BFN
    IVF#3 November 2016 (4 ER, 3 F,  3DT)-BFP  with TWINS // MC both at almost 10wks  :'( 
    IVF#4 March 2017 //EPP  (10 ER (1 wonky so 9 ER) 7F, 3B (5AB, (2)5BB) PGS tested- ALL abnormal  :'( 
    IVF#5 April 2017 // EPP (7 ER, 7F yes! 6B) 2/5 day 4/6 day - 2 PGS normal! yes!! :)
    IVF#6 May 2017 // Antagonist didn't have time for Estrogen Priming...(4 ER, 3 F, 3B) (5AB, (2) 5BB) 2 PGS normal, yes!! :)
    IVF#7 June 2017 // EPP praying this is it and then on to an FET!

  • @Hopeful_mom glad you're feeling better! And I think this is a sign that this should be your LAST trigger!!!!!!!!
    TTC history in spoiler box:
    Me: 42, single
    Hysteroscopy: 2013
    IUI #1-2: 2013 BFN
    Surgery 10/2015: Planned to start trying again but had a surgery. (Not related to fertility)
    Surgery 5/2016: Planned to start trying again but had another surgery. (Not related to fertility)
    IUI  #3-5 (with Clomid): summer 2016 BFN
    IVF #1: 11/2016. 30R; 21M; 20F; 8B (6 day5 & 2 day6); 4 normal after PGS
    Medicated FET #1: 1/31/2017 transferred 1 embryo 3AA. BFP. Embryo stopped growing at 6w 1d. MUA at 9w 3d.
    Medicated FET #2June 2017 - cancelled...
    Hysteroscopy #2: June 2017
    Medicated FET #2: 8/7/2017 transferred 1 embryo 5BB. BFP. Ended in CP.
    Medicated FET #3: 10/11/2017 transferred 1 embryo 3AA. BFN
    ERA: December 2017 - need an extra 12 hours of PIO
    Medicated FET #4: 1/24/2018 transferred 1 embryo 4AA. BFN
    Out of embryos.  :'(
    IVF #2: 03/2018.

    Hopeful_mom
  • I am really sorry, and I feel for you because of the way you feel.  Of course, there many women who have experienced itching and a little of pain at their butt or the leg after receiving a jab. There are also cases where women experience numbness in the in the limbs after receiving the jab. However, these are just some of the symptoms of the trigger which I think should go away on its own. The trigger shot plays a crucial role in sending the egg into a creative division process referred to as meiosis. This is a normal reproductive process which we do not expect to have a big impact. So I suggest that if you are not feeling great, you may have to visit a doc so that further tests can be conducted to establish the cause of the problem. 
    If you had the trigger in the limbs, it is also possible that a nerve was hit. This may cause numbness, and you will not feel great. Consider seeing a medic so that you get advised on how the problem could be solved.

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