Hi everyone. I am starting my first IUI cycle tomorrow and will move onto IVF next month if unsuccessful, so I thought this might be a good place to hang out and get/give any support I can.
(TW: child/pregnancy loss mentioned below)
Background: I am TTC #2 and dealing with secondary infertility, though I imagine our fertility has always been sub-par. We have been TTC this time around actively for a little over a year. We have had one loss @ 9 weeks in November. At our fertility workup with the RE, I came out all good, but my husband was discovered to have low motility and volume (2 semen analyses done). This probably shouldn't have been too much of a shock, he has 2 brothers who have dealt with infertility and a history of a testicular injury. They suggested to start with a clomid IUI cycle, so we did the paperwork, got the meds etc. Our RE is on vacation this week and yesterday we got a call from her coordinator that after the new semen analysis (even though it was better than the first) that her new recommendation is IVF, but that we can do this cycle as is for now since yesterday was CD and I doubt we could get everything set up for IVF in such a short time period, but maybe I'm wrong.
Anyways, after doing some reading, I'm not all that confident in our plan considering the sperm concerns. As of now we are doing clomid 100 mg, ovidrel trigger and IUI. My first monitoring ultrasound is on CD 10 ( I normally ovulate CD 12/13) and I start clomid tomorrow. This process has moved extremely fast for us, our first appt was March 25th, so it's been a bit of a whirlwind.
Thanks for having me, and any feedback, opinions etc are always welcome.
Hello and welcome! Often REs will suggest IVF right off the bat with MFI issues... not because IUI can't be successful it's just a lower success rate. We were told we can do some IUIs first but the best recommendation is IVF... we also have low motility, and low morphology. About to try IUI #3 then move on to IVF if unsuccessful. Feel free to join us over in the May IUI thread, since it looks like maybe your IUI will be in May? I'm looking at starting my cycle next week. Good luck to you!!
***BFP & Child Warning***
Me: 34, DH: 38 ~ TTC since 2014 IUI #1-3 (Nov 2015, Feb 2016, May 2016) = BFNs IVF ER (July 2016) = 7 PGS normal embryos FET #1 (Sept 2016) = BFP! DD born 5/30/17 FET #2 (April 2019) = BFN FET #3 (July 2019) = BFP! DS born 3/27/20
Married May 2009, TTC since November 2012 (Together since 2006 ish - had my eyes on him since 2001)
Me: 32 (33 in May), Him: 37 (January)
DX: Me: High Prolactin, Possible Autoimmune Disease Issues, though RE not concerned (?) New RE has a plan!!
Him: Minor Varicocele, low morphology, slightly low count
History:
Beta 5/9/2016 BFP!! Embryo transfer scheduled for April 28, 2016 and beta test May 9, 2016 (day after Mother's Day!) Transfer Meds include: Lupron Depot (4/1), Minivelle Patch (every 3rd day), Estradiol (3x daily), Amoxicillin, Progesterone in Oil, Methylprednisonlone. Lovenox and baby asprin added after transfer.
3/22/16 - Sono Saline ultrasound cyst to be aspirated on 4/1/16 if not cleared up by 3/29 US - It cleared on its own Retrieval 3/4/16 - 26 eggs retrieved, 23 mature, 20 fertilized, 14 embryos currently frozen Starting IVF Stims on +/- Feb 22, 2016 HSG scheduled for 1-26-16 - All clear "beautiful uterus" (though inverted)
Switched clinics and now prepping for IVF in February / March
I have done 3 Clomid IUIs so far with a MFI issue (morphology). IUI is definitely a boost all around--hopefully you get more eggs from the Clomid so more chance a healthy sperm will meet an egg, the wash and direct injection into the uterus should help a bit as well--but the chances are not like the chances with IVF. It's definitely disheartening to see the statistics, especially when you are about to start an IUI cycle (I remember looking at the charts when I was starting), but it's not nothing. Good luck and fx for you!
About me: /loss mentioned/ TTC#1 July 2014 dx: MFI (morphology) IUI #1 w/Clomid + Ovidrel Sept. 2015 ~ BFN IUI #2 w/Clomid + Ovidrel Halloween 2015 ~ BFN IUI #3 w/Clomid + Ovidrel Thanksgiving 2015 ~ BFP!! hb 146 bpm at 7w5d 1/28/16 ~ began to say goodbye to our beautiful baby at 11w d&c, followed by cytotec TTCAL April 2016 IUI #4 w/Clomid + Ovidrel Apr. 2016 ~ BFN IUI #5 w/Clomid + Ovidrel ~ CP IUI#6 w/Clomid + Ovidrel ~ BFN
Thanks for the welcomes! I guess I'm more hopeful than if we were just trying on our own, so that's what I"m holding on to. I spoke with the nurse earlier and she said we will meet after our IUI and plan for an IVF cycle next cycle should the IUI be unsuccessful. Marching forward!
Re: Intro: child/pregnancy/loss mentioned
Me: 34, DH: 38 ~ TTC since 2014
IUI #1-3 (Nov 2015, Feb 2016, May 2016) = BFNs
IVF ER (July 2016) = 7 PGS normal embryos
FET #1 (Sept 2016) = BFP! DD born 5/30/17
FET #2 (April 2019) = BFN
FET #3 (July 2019) = BFP! DS born 3/27/20
Beta 5/9/2016 BFP!!
Embryo transfer scheduled for April 28, 2016 and beta test May 9, 2016 (day after Mother's Day!)
Transfer Meds include: Lupron Depot (4/1), Minivelle Patch (every 3rd day), Estradiol (3x daily), Amoxicillin, Progesterone in Oil, Methylprednisonlone. Lovenox and baby asprin added after transfer.
3/22/16 - Sono Saline ultrasound cyst to be aspirated on 4/1/16 if not cleared up by 3/29 US - It cleared on its own
Retrieval 3/4/16 - 26 eggs retrieved, 23 mature, 20 fertilized, 14 embryos currently frozen
Starting IVF Stims on +/- Feb 22, 2016
HSG scheduled for 1-26-16 - All clear "beautiful uterus" (though inverted)
Switched clinics and now prepping for IVF in February / March
Trying to conceive since November 2012
Me: 40, DH: 35 / Married: 2009; TTC #1: 2013
2013 - 2015: 5 pregnancies —> 5 miscarriages
TTCAL with RE (RPL specialist): February 2016
2016: 3 medicated TI cycles —> 3 medicated IUI cycles: All BFN
Donor Egg IVF Transfer: May 1, 2017
May 11, 2017: BFP!! Beta #1: 449.1, Beta #2: 844, Beta #3: 1714
EDD: 1/17/18, it's a GIRL! E. L. A. born 12/7/2017
/loss mentioned/
TTC#1 July 2014
dx: MFI (morphology)
IUI #1 w/Clomid + Ovidrel Sept. 2015 ~ BFN
IUI #2 w/Clomid + Ovidrel Halloween 2015 ~ BFN
IUI #3 w/Clomid + Ovidrel Thanksgiving 2015 ~ BFP!!
hb 146 bpm at 7w5d
1/28/16 ~ began to say goodbye to our beautiful baby at 11w
d&c, followed by cytotec
TTCAL April 2016
IUI #4 w/Clomid + Ovidrel Apr. 2016 ~ BFN
IUI #5 w/Clomid + Ovidrel ~ CP
IUI#6 w/Clomid + Ovidrel ~ BFN