New to the Infertility Board- Loosing hope- Hoping for Advice/Support

babycarrott

I just found out that my 5th IUI failed. For a short background, I have been pregnant three times before, twice on my own and once via IUI. All three ended in miscarriage during the first trimester. I have unexplained infertility as a diagnosis. After my third IUI resulted in a pregnancy and then a loss, I decided to try IUI again. The past two times have been with a higher dose of clomid and progesterone with no luck. I can do one more round of clomid and another IUI if I choose. IVF may be the next step. I am 33 years old.

I have had all forms of testing and everything comes back fine. My husband has been tested and after sperm washes his sperm count and motility is more than perfect.

I guess I am looking for advice/support. Any one here go on to have successful IVF after so many IUI's? I am just wondering if it is worth it to spend all that money just to end in miscarriage again. I know how horrible that sounds but I don't think I can handle another miscarriage. This process is HARD!! There are days I want to throw in the towel  but giving up is even harder to do. 

MKLEWIS2010

Hi I am sorry for your losses. I do not know too much about this topic, however from what I read about miscarriages it could be anything from chromosomal abnormalities with the embryos to your body rejecting the pregnancy. What has your RE said about the miscarriages?  Have you seen a Reproductive Immunologist?  I have read that they can help diagnose these types of issue. 

Also IVF may be a good option this way you can do genetic testing on the embryos before the transfer. If there is a genetic or chromosomal issue they will know before they transfer the embryo.  

Hang in there and best wishes to you on this difficult journey. 

babycarrott

Thank you! I have had chromosomal testing and so has my husband, it all came back negative for abnormalities. I have been seeing a REI for about 10 months. After my last miscarriage I even had chromosomal testing done on the baby and everything came back normal. 

I agree about the IVF. It has been pointed out to me that the egg retrieval could help answer any questions the doctors have and may increase my chances since they will fertilize many eggs.

Thank you for your kind words and support. I truly appreciate it.

MrsBwIVF

Bfp, loss mentioned

Yes, agree with PP.
You said you've had testing for everything, did that include a blood test for MTHFR mutation?
We had a loss, unexplained infertility, failed iuis, successful ivf that ended in twin loss. We felt the same way you did! I was terrified to do another ivf cycle, fearing I'd lose another child. We decided to do the genetic testing and the only thing they found was I have the MTHFR mutation. We looked it up and I had about half of the things listed on what it can cause within your body, like fatigue, bowel issues, frequent headaches, and then unexplained infertility. Now, our Dr explained that the doctors are all about 50/50 split on if it does affect fertility but she put me on folic acid and baby aspirin regiment just in case.
I don't know if that is what helped us over the hump but it was the only thing that changed. We are currently 15w4d with healthy twins.

Whenever I hear or read on here someone who has a similar struggle to me, I always suggest they get tested for the mutation. If it is indeed why this pregnancy is sticking, it was such an easy and cheap fix and I want more woman to know about it.

Good luck on your journey. And know, you're not alone. Always allow yourself to vent and cry out your frustrations. I like to cry it out in the shower and clear my head for the day.

babycarrott

Thank you everyone so very much!!! I really needed to hear those words of encouragement, good vibes and prayers.

@Mrs.BwIVF I wasn't sure if I had been tested for the MTHFR mutation so I asked my doctor. He was going to double check and get back to me. I am already on a baby aspirin regime, so he said if I did have it, the aspirin would help. Thanks for the info!! Much appreciated! I am willing to try anything at this point.

HCG this morning confirmed what I knew with HPT, BFN However, I had a long talk with my doctor about the next steps. He would really like me to try clomid and IUI again. It will be my sixth time since November of last year. He said that since I got pregnant before this way he wants to give it another shot before we go to the much more invasive IVF. We also talked about doing a trigger shot this cycle. While I don't have problems ovulating this would help timing of the IUI. 

So I will stop the progesterone and wait for my period to rear its ugly head and start the process again. Keeping my fingers crossed for all of us!!!

lovelifewife

So sorry for the losses. Keeping the hope for you that this is a good month.

MKLEWIS2010

You're welcome @babycarrott I wish you success in this journey and if you ever need to vent we are here. Good luck!