MTHFR gene mutation, 35 yrs old, and I'm about 4 weeks pregnant- need advice

unitykr

Hi Moms and Moms-to be,
I found out I have the MTHFR gene mutation, which can cause among other things, multiple miscarriages due to blood clotting issues. I also do not process Folic Acid properly. I read up and found that L-Methylfolate is best to take, as it is a non-synthetic folate supplement. I read up some more about some things I should have done to prepare for a pregnancy, such as taking the right supplements and possibly taking anticoagulants like Lovenox. Well here I am pregnant, and I want to proceed the best way possible. I just started taking a baby aspirin and bought a prenatal with L-Methylfolate. I have a dr. appointment in two weeks to discuss everything further with my OBGYN.  This is my third pregnancy, I lost the first two very early (before 6 weeks). Does anyone with the MTHFR gene mutation have advice and can speak from experience regarding a pregnancy regiment? Thanks in advance!

BlueJell0

There are probably some MTHFR ladies here, but none of us are pregnant. PAIF or PgAL would be a better place for this question. Good luck OP.

tumbleweed123

unitykr  you should definitely jump over to Pregnant after IF - none of us here is pregnant.  But, since I have the MTHFR mutation, I wanted to offer up some advice.  All your research is correct.  L-methylfolate is the way to go.   You should speak to your doctor about the aspirin and possible injections of Lovenox, if you have the double mutation.  If you have the single, they might just have you on baby aspirin.  But, always check with your doc before starting any meds.  You could just give them a call and ask if it is ok to take the aspirin, based on your past losses and mthfr mutation.  You should also make sure to have your B-12 and B-6 tested, because mthfr ladies often lack those too.  H&H 9 months to you. Now, go over to PAIF. 

eta: spelliing

chicagobride_07

SIggy warning, SAIF response: I am homozygous for the MTHFR mutation. As you can see from my siggy, I have a long and complicated history. With DD (who was the result of an FET in 2012), I was not aware of this, and did nothing, and had no clotting related complications. I've had 4 failures with our attempts for a sibling since then and found out that I had MTHFR through follow up testing with a reproductive immunologist. The RI suggested Metanx, baby aspirin and lovenox. GL to you!

kreardon11

Check out MTHFR.net

I'm on BA, Vital Nutrients Prenatal w/ 5-mthf, ProDHA, and NO dairy/egg/wheat. A lot of MTHFR folks have food sensitivities. I'm doing a juice cleanse next week to ramp up TTC and then DH and I are starting again. I've had two losses <7 weeks. 

przemosbabe

I am not pregnant but take lovenox, baby asprin and a prescription prenatal with a folate in it because when you have this mutation I think your body also has trouble absorbing folic acid. I hope we have all been of some help despite not being pregnant. Good luck to you.