Infertility

Introduction *** Losses Mentioned ***

Hi everyone! I'm starting my first cycle and decided it would be nice to meet some other women who can commiserate. I feel like I could write a book about everything that has happened (probably like most of you), but I'll try not to do that here :)

I came to IVF in a kind of roundabout way. I've had 3 unexplained losses. After loss 2, I discovered I have premature ovarian aging (I'm 34). My FSH was not too bad (about 10) but my AMH was .49. A few months after loss 3, I had a little freak out, because I started to feel like menopause was breathing down my neck. My cycles now average 34 days. AF is super light and short now, sometimes only a day and a half. I've been getting hot flashes and I soak the bed with sweat every night. I just feel like my clock doesn't have enough time on it to keep trying or to have another loss.

I picked a new RE to discuss options (my old RE said things like, "You're losing fertility every day you aren't pregnant!!" which may be true, but is not helpful). I was thinking I could see how many embryos I get, then decide if I had enough to risk one on myself or go with a GC. 

At first (before my ultrasound) he was optimistic. He said there's no need for a GC, that I should get plenty of healthy embryos. At my US we discovered that I only had a total AFC of 3 and he recommended "family building" where I do 3 ERs in a row in the hopes of getting a healthy embryo for one FET. From what I've ready, many REs don't recommend IVF for patients with only 3 follies. I think the idea of family building is they go through with ER even if I only have a few mature follies since we are already planning to do three. And I get a discount for buying three up front.

He also found I have a small septum, and he recommends I get it removed before FET. And my uterine blood flow is not great. I start estrogen priming with testosterone Monday, and first ER should be beginning of December. FET is estimated for (groan) May if all goes well. I'm hopeful, but frankly pretty cautious about getting excited. If I get one or two embies, I may go back to considering a GC. I'm afraid to waste them on my crazy body.

*** losses discussed in more detail below ***



I know this isn't the TTCAL board, but here is some more info on my losses anyway: I lost one at 9 weeks (no chromosome analysis done), one at 15 weeks (test came back normal female), and quadruplets at 8 weeks (normal males). The quads were identical (mono/tri), and two were conjoined. My first RE kept insisting that the losses were caused by my POA, but that doesn't totally make sense since the two chromosome tests were normal.

My new RE says the first and third may have been flukes (4 babies with one placenta can't be good, and the first may have been chromosomes). But the second one worries him, and that's why he recommended the septum resection, even though it's small. He also recommends CCS.



***  Losses Mentioned ***

Me: 35 this month DH: 35

TTC since January 2013

2/13: BFP  4/13: MC @ 9 weeks - D&C - no chromosome testing
7/13: BFP  10/13: MC @ 3 1/2 months - D&C - chrom test normal

11/13: 1st RE visit for testing only - AMH .4 - FSH 11 - positive MTHFR (one copy)

2/14: BFP 4/13 (identical mono/tri quads, 2 conjoined) - MC @ 8 weeks - D&C - chrom test normal

10/14: RE 2nd opinion & IVF consult - Dx small uterine septum - AFC 3 total - recommended banking 3 ERs - DH slightly low morphology
12/14: First ER cycle - EPP w/testosterone, Lupron microflare w/Saizen. 4R/3M/2F. Both abnormal. RE strongly recommends donor eggs.

 image


Re: Introduction *** Losses Mentioned ***

  • Hi! Thanks for the well wishes. Good luck with your ER, too! Sounds like it's happening soon.

    ***  Losses Mentioned ***

    Me: 35 this month DH: 35

    TTC since January 2013

    2/13: BFP  4/13: MC @ 9 weeks - D&C - no chromosome testing
    7/13: BFP  10/13: MC @ 3 1/2 months - D&C - chrom test normal

    11/13: 1st RE visit for testing only - AMH .4 - FSH 11 - positive MTHFR (one copy)

    2/14: BFP 4/13 (identical mono/tri quads, 2 conjoined) - MC @ 8 weeks - D&C - chrom test normal

    10/14: RE 2nd opinion & IVF consult - Dx small uterine septum - AFC 3 total - recommended banking 3 ERs - DH slightly low morphology
    12/14: First ER cycle - EPP w/testosterone, Lupron microflare w/Saizen. 4R/3M/2F. Both abnormal. RE strongly recommends donor eggs.

     image


  • Thank you. Good luck to you too!

    ***  Losses Mentioned ***

    Me: 35 this month DH: 35

    TTC since January 2013

    2/13: BFP  4/13: MC @ 9 weeks - D&C - no chromosome testing
    7/13: BFP  10/13: MC @ 3 1/2 months - D&C - chrom test normal

    11/13: 1st RE visit for testing only - AMH .4 - FSH 11 - positive MTHFR (one copy)

    2/14: BFP 4/13 (identical mono/tri quads, 2 conjoined) - MC @ 8 weeks - D&C - chrom test normal

    10/14: RE 2nd opinion & IVF consult - Dx small uterine septum - AFC 3 total - recommended banking 3 ERs - DH slightly low morphology
    12/14: First ER cycle - EPP w/testosterone, Lupron microflare w/Saizen. 4R/3M/2F. Both abnormal. RE strongly recommends donor eggs.

     image


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  • I am sorry for your losses, FX for your next cycles :)
    TTC since May 2013, w/ RE since July 2014

    Me: 33 Poor responder, Low AMH
    DH: 32 Severe MFI 
    09/2014 IVF #1 - Antagonist Protocol - 2 immature eggs
    11/2014 IVF #2 - Micro Flare Lupron - 3 immature eggs
    Please forgive my writing mistakes, english is my second language.
    imageimage


  • Welcome and I am so sorry for your losses. Best of luck with the upcoming ER.
  • Welcome. I'm so sorry for your losses, as I know how hard and frustrating going through each is. I hope your stay is short and you get some answers soon.

     

    image



    Married: 8/25/13 - TTC #1 since May 2013 - Met with RE June  2014
    BFP #1 August 2013 - Suspected Ectopic September 2013
    BFP #2 May 22, 2014 - MC May 27, 2014
    BFP #3 June 30, 2014 - MC July 6, 2014
    BFP #4 IUI cycle #1 October 10th - ectopic identified October 24th
    ****Looking to start IVF next round since I've had 2 ectopics*** 
  • Welcome. I'm so sorry for your losses, it sounds like moving to the new RE was a good choice. 
    If it makes you feel better at all, I'm 30 and have a hormonal imbalance, which I'm sure is common around here. So my cycles are usually 30-37 days and last about a day and a half. And I've been getting hot flashes since I was about 17. :( So it very well could just be your body working things out. 

    Good luck with your next round, fx!
  • Welcome. You've been through so much, I'm sorry for your losses. ((Hugs))
    Me: 30 DH: 30 ~ TTC #1 Since August 2011 
    BFP #1 2/28/13, Ectopic, Tubal surgery 3/25 
    Began RE testing 8/8, Dx Unexplained, 
    IUI #1 11/1=BFN Moving on to IVF 
    IVF #1 12/2 ER 8R 7M 4 fertilized
    12/7 Transferred 2 "perfect" little blasts 12/17 BFN
    New DX= DOR, I fu*kng hate IF
    1/14 Hysteroscopy, new clean uterus!
    IVF #2: bcp, Lupron, follistim 300, menopur 225. 2/21 8R 4M 3F. 3dt of 2 perfect embryos. 1 little penguin 
     3/10 BFFN
    Regrouping. Seeing reproductive immunologist Dr. Kwak Kim 6/10 
    Kwak Kim protocol: Metformin 1000mg, vitamin D 4000iu, vitamin E 400iu, baby aspirin, Metanx, levothyroxine 75mcgs 
     Surprise BFP 9/21!!! Beta #1 247, Beta #2 630. Miscarried 10/13

  • You have been through alot (((HUGS))). I'm so sorry for your losses. You are very welcome here.
  • Thanks for all the welcome posts everyone!

    ***  Losses Mentioned ***

    Me: 35 this month DH: 35

    TTC since January 2013

    2/13: BFP  4/13: MC @ 9 weeks - D&C - no chromosome testing
    7/13: BFP  10/13: MC @ 3 1/2 months - D&C - chrom test normal

    11/13: 1st RE visit for testing only - AMH .4 - FSH 11 - positive MTHFR (one copy)

    2/14: BFP 4/13 (identical mono/tri quads, 2 conjoined) - MC @ 8 weeks - D&C - chrom test normal

    10/14: RE 2nd opinion & IVF consult - Dx small uterine septum - AFC 3 total - recommended banking 3 ERs - DH slightly low morphology
    12/14: First ER cycle - EPP w/testosterone, Lupron microflare w/Saizen. 4R/3M/2F. Both abnormal. RE strongly recommends donor eggs.

     image


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