Hi ladies, I'm just about to start my first FET cycle and I've been reading a lot of different protocols on here and other websites for FET cycles, all that involve Vivelle patches and antibiotics, baby aspirins, lupron, medrol, etc. My Dr basically has me taking birth control pills for another week, until I start the placebo week (week 4 of birth control), and then, when I start day one of my cycle, he wants me to take 2mg Estradiol three times per day for 2 weeks. After 2 weeks, I go in for an ultrasound of my lining and if it's "getting there", I'll start vaginal progesterone for three days until the transfer (and after the transfer until the beta). Just given that I've seen so much other 'stuff' that can be done with FET protocols, do you think that my Dr is being too minimalist with the meds? I don't mind not being over-drugged, but I just don't want to waste an embryo on lining that isn't optimal because I was under-medicated... What do you ladies think? Has anyone else only done estradiol with a little bit of progesterone at the end?
Married 07/2006, TTC since 2010 08/2011: Clomid 50mg, IUI --> BFN , 10/2011: Clomid 100mg, IUI --> BFN 04/13: Clomid, IUI BFP --> MC at 6w1d 05/13: Femara 2.5mg, IUI --> BFN , 08/13: Femara 2.5mg --> BFN 03/14: Femara 5mg, IUI --> 1 follicle @ 27d --> BFP! EDD 12/02/14--> blighted ovum, missed MC 6w6d --> D&C 4/23: D&C...starting over again, with a little part of my heart broken off
5/31: Femara 7.5mg --> cancelled cycle, no follies 7/14: Femara 5mg + brevelle + menopur + IUI --> converted to IVF, ER 7/28 --> ET cancelled due to severe OHSS. 9/20/14: Frozen Embryo Transfer --> BFP--> EDD 6/6/15 --> MC at 5w3d 10/16/14: Frozen Embryo Transfer --> BFN 2/6/15: Frozen Embryo Transfer --> BFP --> MC at 5w4d 3/20/16: PGS-tested Frozen Embryo Transfer --> BFP, Living Child born 12/1/15 6/6/17: Fresh IVF Cycle --> Severe OHSS, 5 PGS-tested embryos frozen 2/23/18: PGS-tested FET --> BFN 3/30/18: Cancelled cycle due to lining 4.2mm
That is what my Dr. has planned for my FET (minus the BCP), but I had already been taking baby aspirin with my other cycles and he was fine with me starting up again.
I'm currently in an FET cycle and I'm only doing Estrace (3x day) and a baby asprin (1x a day) I started Estrace once a day (for 5 days) , then went up to twice a day (for four days) and am now finally doing three times a day. Progesterone just started and transfer will be on Friday.
For me, it's a welcome change from the overabundance of meds. It's been a nice, boring cycle so far. My lining was just fine at my check last Friday. I would assume if, at the check, things weren't as thick, they could up the dosage as needed before transfer.
Yup, this is what my clinic does, too, not even including the vaginal estrogen or the BCP (although I took a few for scheduling issues). You'll likely get antibiotics and Medrol in the last few days leading up to transfer, but not necessarily. They said that sometimes they'll do more if women have a history of poor linings, and I guess some clinics just go more aggressively for everyone.
***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen. => M/C @ 8 wks. Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
Just goes to show how very different protocols can be. I finished BCP after starting lupron and am working my way up to 4 minivelle patches over the next week or so. I have one lining check 9/5 with b/w and only b/w on 9/10 for a 9/12 transfer. I've been on baby aspirin and will take keflex and medrol.
You'll do just fine- this process so far seems much easier than the fresh ones!
**Signature Warning**
Dx PCOS August 2012
Clomid x4 = BFN
Femara+Follistim IUIs x 6 = 3 BFN, 2 C/P, 1 early miscarriage
IVF June 2014- 43 R, 34 M, 24 F, 12 blasts frozen and severe OHSS
FET September 12, 2014!
Beta #1 12dp5dt- 724
Beta #2 14dp5dt- 1631
Beta #3 20dp5dt- 12,813
Pending EDD at first OB appointment 11/6. Grow babies grow!
"I might have to wait. I'll never give up. I guess it's half timing, and the other half's luck.
Wherever you are, whenever it's right, you'll come out of nowhere and into my life." ~ Michael Buble
Thanks for the input ladies! It can be so daunting reading so many different protocols and then wondering 'should I be on this?' or 'should I be on that'? I'm definitely okay with not taking as many meds...as long as it works. After having such a rough IVF leading to ER in July, I just don't want to 'waste' any of my embryos. It's reassuring to know that others are doing estradiol alone :-)
Married 07/2006, TTC since 2010 08/2011: Clomid 50mg, IUI --> BFN , 10/2011: Clomid 100mg, IUI --> BFN 04/13: Clomid, IUI BFP --> MC at 6w1d 05/13: Femara 2.5mg, IUI --> BFN , 08/13: Femara 2.5mg --> BFN 03/14: Femara 5mg, IUI --> 1 follicle @ 27d --> BFP! EDD 12/02/14--> blighted ovum, missed MC 6w6d --> D&C 4/23: D&C...starting over again, with a little part of my heart broken off
5/31: Femara 7.5mg --> cancelled cycle, no follies 7/14: Femara 5mg + brevelle + menopur + IUI --> converted to IVF, ER 7/28 --> ET cancelled due to severe OHSS. 9/20/14: Frozen Embryo Transfer --> BFP--> EDD 6/6/15 --> MC at 5w3d 10/16/14: Frozen Embryo Transfer --> BFN 2/6/15: Frozen Embryo Transfer --> BFP --> MC at 5w4d 3/20/16: PGS-tested Frozen Embryo Transfer --> BFP, Living Child born 12/1/15 6/6/17: Fresh IVF Cycle --> Severe OHSS, 5 PGS-tested embryos frozen 2/23/18: PGS-tested FET --> BFN 3/30/18: Cancelled cycle due to lining 4.2mm
For FET#1 I was on Lupron and estrace pills (oral and vaginal) with PIO (progesterone in oil) starting a few days before transfer. This time, I'm only taking estrace for now until it's time for the PIO. You're definitely not the only one!
I was prescribed steroids and antibiotics right before my planned fresh transfer (that was cancelled). They weren't prescribed for my FET though.
Best of luck to you!
**warning**
Me (31), DH (33), one furbaby (7) - unexplained IF
hysteroscopy and polypectomy 2/14
IVF #1 3/2014 - cancelled (early ovulation)
IVF #1.2 ER 5/16/14: 23R 18F - freeze all (12) due to concern for late onset OHSS
FET #1 in June - delayed due to thin lining, 7/18 SET (7.5 mm lining) resulted in chemical pregnancy
FET #2 in Sept - 9/4 transferred 2 CCS tested embryos (6.5mm lining)
9/13 beta #1 - 400, 9/15 beta #2 - 950, U/S 9/22 one gestational/yolk sac - next up 9/29
It really depends on the clinic. My clinic uses BCP, lupron, dex or prednisone, cipro, estrogen, and PIO. I've never actually done an FET with them because I've never had anything to freeze. The clinic I did my donor embryo cycle through used estrace or vivelle, cipro, and PIO.
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
Re: Should I be concerned...only Estradiol for FET cycle...
For me, it's a welcome change from the overabundance of meds. It's been a nice, boring cycle so far. My lining was just fine at my check last Friday. I would assume if, at the check, things weren't as thick, they could up the dosage as needed before transfer.
IVF #2: April 2014 Antagonist Protocol|12R 11M 10F|Transfer 2|BFP | m/c 5.8.14
U/S shows two beautiful heartbeats at 122!!
Baby A is our stubborn little fighter with a heartrate of 169!
Team BLUE!
No need to worry!
***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen. => M/C @ 8 wks. Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
You'll do just fine- this process so far seems much easier than the fresh ones!
After having such a rough IVF leading to ER in July, I just don't want to 'waste' any of my embryos. It's reassuring to know that others are doing estradiol alone :-)
08/2011: Clomid 50mg, IUI --> BFN ,
10/2011: Clomid 100mg, IUI --> BFN
04/13: Clomid, IUI BFP --> MC at 6w1d
05/13: Femara 2.5mg, IUI --> BFN , 08/13: Femara 2.5mg --> BFN
03/14: Femara 5mg, IUI --> 1 follicle @ 27d --> BFP! EDD 12/02/14--> blighted ovum, missed MC 6w6d --> D&C
4/23: D&C...starting over again, with a little part of my heart broken off
7/14: Femara 5mg + brevelle + menopur + IUI --> converted to IVF, ER 7/28 --> ET cancelled due to severe OHSS.
9/20/14: Frozen Embryo Transfer --> BFP--> EDD 6/6/15 --> MC at 5w3d
10/16/14: Frozen Embryo Transfer --> BFN
2/6/15: Frozen Embryo Transfer --> BFP --> MC at 5w4d
3/20/16: PGS-tested Frozen Embryo Transfer --> BFP, Living Child born 12/1/15
6/6/17: Fresh IVF Cycle --> Severe OHSS, 5 PGS-tested embryos frozen
2/23/18: PGS-tested FET --> BFN
3/30/18: Cancelled cycle due to lining 4.2mm
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!