Ganirelix is a pretty easy injection. It doesn't burn like Menopur, and there's no assembly process.
But yeah... it's not the best needle. I personally found it easier to insert into the thigh than into the stomach, although I was more likely to get a skin reaction on the thigh. For me, NO needle was as bad as the ones that came with my two-week Lupron kit. Seriously, it was like inserting a spork into my belly fat.
Overall, though, Ganirelix is really nothing to fret about
Me: 34 / DH: 33
19-year history of endometriosis. Multiple surgeries and cyst removals. Forced directly into IVF due to blocked tubes and severe adhesions.
IVF w/ICSI and CCS #1 - Dec 2013 - Only 1 normal. Ended in CP
I thought it burned a LOT!!!! It took a moment to notice, then OW!!!! When I googled it, it seems like some people are bothered, some aren't. You could do the first run like a normal shot to see how you react. If it burns for you, try the ice trick.
***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen. => M/C @ 8 wks. Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
I guess we're cycle twins @ronniesgirl1981. I got the same instructions after my monitoring appointment today. The needle isn't so bad. It did burn a little to me but not as much as the Menopur.
I thought the needle was definitely blunt compared to the gonal-f ones I had been using beforehand. I had some burning for up to a half hour after, but nothing too bad.
**warning**
Me (31), DH (33), one furbaby (7) - unexplained IF
hysteroscopy and polypectomy 2/14
IVF #1 3/2014 - cancelled (early ovulation)
IVF #1.2 ER 5/16/14: 23R 18F - freeze all (12) due to concern for late onset OHSS
FET #1 in June - delayed due to thin lining, 7/18 SET (7.5 mm lining) resulted in chemical pregnancy
FET #2 in Sept - 9/4 transferred 2 CCS tested embryos (6.5mm lining)
9/13 beta #1 - 400, 9/15 beta #2 - 950, U/S 9/22 one gestational/yolk sac - next up 9/29
The needle does seem harder to get in then others so I do think the needle was duller. I didn't have any burning. And honestly, with the dull needle I only had an issue twice where it just bounced off my belly instead of puncturing the skin so all I had to do was try again and use more force. As for once it goes in - not any harder or hurt any more than doing follistim or menopur.
Seriously - after ALL of the injects you've been through - this is nothing. It actually just becomes a part of your routine. Wake up, brush teeth, inject hormones into your stomach, eat breakfast. You know - a natural part of your day! Ganirelix just replaces your morning coffee. Wasn't that nice of the RE to give you such an awesome substitution?
I had no ill effects and it was SOOOO nice not having to mix and change needles before work as I am usually already running late.
You are an inject pro - YOU GOT THIS girl!!!!
***Siggy Warning***
Me: 35 DH: 34 TTC since May 2012 Unexplained Infertility IUI#1 October 2013- 58m post wash - BFN IUI#2 November 2013- 39m post wash - BFN IUI#3 January 2014- 33m post wash - BFN IVF #1 March 2014- 23R/18F/ZERO Frosties -BFN IVF #2 May 2014 - 17R/14F/1 frozen pea (2-8 cell 10% fragmentation day 3)BFP Beta #1 77.7 (13dp3dt) Beta #2 307 (17dp3dt) Beta #3 695 (19dp3dt) Beta #4 2232 (23dp3dt)
I did have a bit of a reaction to the Ganirelix the first 2 times I injected it but after I googled about it realized that it was very common. I had a little burning but mainly it was itchy and I got like a raised welt in the area where I injected it. It only lasted a few hours but it freaked me out at first.
After that it was easy peasy, although it did seem to be the dullest of the needles I had.
Its not the worst one but it is dull. I'm on day 2 of it for this cycle. I was able to give it to myself today. GL
***SIGGY WARNING***
DX: Unexplained
6 Failed IUIs (Clomid and Gonal F).
IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN, IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1 BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical
Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg. Endo biopsy=negative. WTF is wrong with us???
12/18/13 FET of 1 BB and 1 AC. Hoping for a miracle. Beta 12/26 Low BETA-8 2nd BETA 5- chemical
After 3 failed transfers IDK where to go from here. Still no real answers as to why this isn't working. Getting a second opinion in February and looking into immune testing.
2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer. 3/14 Lupron, gonal f, menopur, HGH. ER 15 mature all 15 fertilized! 5dt of an early blast grade 1 and an expanded blast grade 2. BETA on 4/21. 1 grade 2 embryo frozen BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121. US at 8w3d measuring on track HR 177. Released form my RE. EDD 12/28
I must have been an oddball. I too thought the needle sucked, but I got so stinking sick from G. I threw up within 2 hours of my first injection and took me about 2 days to readjust...
Best of luck, I hope I'm just weird and you'll have the luck of the other ladies here!
I remember (not that it was so long ago) that I had to push a little harder to get the needle in, but the plunger was much faster than my other needles which made for a super fast shot. Good luck!
***BFP and Loss Mentioned in Siggy***
Me: 39 (PCOS) DH: 47 (slightly low volume...considered MFI) TTC since 11/2012 10/2013: IUI#1 BFN - 50mg clomid, two .75mg shots of Bravelle, ovidril trigger...1 follicle 11/14/13: IUI#2 BFN - 50mg clomid, two .75 mg shots of Bravelle, ovidrill trigger..2 follicles
IVF #1 w/ICSI: ER 3/12/14; ET 3/17/14: BFP!!! Beta #1 3/31/14=1540; Beta #2 4/2/14 =2551
Thanks everyone! Last's night shot burned like hell, but today was totally fine. I told my husband that you ladies had warned that the needle was dull and he rolled his eyes. 5 seconds later, "oh, it is dull."
My husband rolled his eyes when I started flicking the needle to get the bubbles out. He always thought that it was something they only did on TV. After I explain that it was legit, he became the official 'flicker' when I did shots. LOL
***BFP and Loss Mentioned in Siggy***
Me: 39 (PCOS) DH: 47 (slightly low volume...considered MFI) TTC since 11/2012 10/2013: IUI#1 BFN - 50mg clomid, two .75mg shots of Bravelle, ovidril trigger...1 follicle 11/14/13: IUI#2 BFN - 50mg clomid, two .75 mg shots of Bravelle, ovidrill trigger..2 follicles
IVF #1 w/ICSI: ER 3/12/14; ET 3/17/14: BFP!!! Beta #1 3/31/14=1540; Beta #2 4/2/14 =2551
IVF prep September 2013 cancelled due to Ovarian Cyst IVF #1 October 2013 Antagonistic Protocol with ICSI ER 10/31/13 (18R 16M 11F- 6 blasts to freeze) ET delayed due to OHSS FET scheduled for July 8. Delayed due to a crazy high TSH (it had been under control for YEARS!) FET #1 8/5/14 sET BFN
Re: Ganirelix
IVF #1 Oct 2013- cancelled
IVF #2 Mar 2014- success.... baby girl born 11/28/14
FET #1 Mar 2016- baby boy due 12/16/16
TTC since 08/2012
DX: DOR
Good luck!
***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen. => M/C @ 8 wks. Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
TTC since 08/2012
DX: DOR
dx: Unexplained IF
TTC since May 2011, 1 year trying, and then 3 TI, 2 IUI = BFN
IVF #1 (May 2013): Antagonist Protocol:
24R, 18M, 15F w/ICSI; 5dt of 2 early blasts, no frosties = BFN
IVF #2 (August 2013): Lupron Stop Protocol:
28R, 23M, 15F w/ICSI; 5dt of 1 partially hatched blast, 7 frosties = BFP
EDD 5/23/14, blighted ovum (6w6d), D&C (8w6d)
FET #1 (April 2014): transferred 2 5d blasts = BFP
C.J. born 01/09/15
IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
IUI#5 BFN (April 2013)
S/PAIFW , S/PALW
My Blog
TTC since 08/2012
DX: DOR
***Siggy Warning***
Me: 35 DH: 34
TTC since May 2012
Unexplained Infertility
IUI#1 October 2013- 58m post wash - BFN
IUI#2 November 2013- 39m post wash - BFN
IUI#3 January 2014- 33m post wash - BFN
IVF #1 March 2014- 23R/18F/ZERO Frosties - BFN
IVF #2 May 2014 - 17R/14F/1 frozen pea (2-8 cell 10% fragmentation day 3) BFP
Beta #1 77.7 (13dp3dt)
Beta #2 307 (17dp3dt)
Beta #3 695 (19dp3dt)
Beta #4 2232 (23dp3dt)
1 Beautiful Baby - EDD 1/28/15
After that it was easy peasy, although it did seem to be the dullest of the needles I had.
Good luck! You'll be fine!
dream 1 CAME TRUE 2.13.2010
<dream 2> 12.2011
2.10.12 : 4 weeks
6.17.12 : 10 weeks
10.10.12 : 4 weeks, 6 days
12.13.12 : 9 weeks, 1 day
4.6.13 : 4 weeks, 4 days
10.27.13 : 5 weeks, 6 days
4.2.14 (IVF #1) : 4 weeks, 1 day
6.19.14 : IVF #2 Negative
</dream 2>
resolve.org
lyrics
***All always welcome!!***
DX: Unexplained
BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121. US at 8w3d measuring on track HR 177. Released form my RE. EDD 12/28
I must have been an oddball. I too thought the needle sucked, but I got so stinking sick from G. I threw up within 2 hours of my first injection and took me about 2 days to readjust...
Best of luck, I hope I'm just weird and you'll have the luck of the other ladies here!
***BFP and Loss Mentioned in Siggy***
Me: 39 (PCOS)
DH: 47 (slightly low volume...considered MFI)
TTC since 11/2012
10/2013: IUI#1 BFN - 50mg clomid, two .75mg shots of Bravelle, ovidril trigger...1 follicle
11/14/13: IUI#2 BFN - 50mg clomid, two .75 mg shots of Bravelle, ovidrill trigger..2 follicles
IVF #1 w/ICSI: ER 3/12/14; ET 3/17/14: BFP!!! Beta #1 3/31/14=1540; Beta #2 4/2/14 =2551
Twin A became an angel on 4/30/14 (8w6d)
Twin B became an angel on 5/21/14 (11w6d)
D&C 5/23/14
FET#1 - 9/2/14 - BFP!!! Beta #1 (9/15): 926. Beta #2 (9/17): 1946.
MC -9/20/14FET#2 - 4/20/15 - BFP!!! Beta #1 (5/4): 1277. Beta #2 (5/6): 2817. US#5 -153 heartbeat.
Due Date: January 6, 2016
TTC since 08/2012
DX: DOR
***BFP and Loss Mentioned in Siggy***
Me: 39 (PCOS)
DH: 47 (slightly low volume...considered MFI)
TTC since 11/2012
10/2013: IUI#1 BFN - 50mg clomid, two .75mg shots of Bravelle, ovidril trigger...1 follicle
11/14/13: IUI#2 BFN - 50mg clomid, two .75 mg shots of Bravelle, ovidrill trigger..2 follicles
IVF #1 w/ICSI: ER 3/12/14; ET 3/17/14: BFP!!! Beta #1 3/31/14=1540; Beta #2 4/2/14 =2551
Twin A became an angel on 4/30/14 (8w6d)
Twin B became an angel on 5/21/14 (11w6d)
D&C 5/23/14
FET#1 - 9/2/14 - BFP!!! Beta #1 (9/15): 926. Beta #2 (9/17): 1946.
MC -9/20/14FET#2 - 4/20/15 - BFP!!! Beta #1 (5/4): 1277. Beta #2 (5/6): 2817. US#5 -153 heartbeat.
Due Date: January 6, 2016
TTC since 08/2012
DX: DOR
Me: 32 H: 31
IVF #1 October 2013 Antagonistic Protocol with ICSI ER 10/31/13 (18R 16M 11F- 6 blasts to freeze)
ET delayed due to OHSS
FET scheduled for July 8. Delayed due to a crazy high TSH (it had been under control for YEARS!)
FET #1 8/5/14 sET BFN