Infertility

What do you know about autoimmune diseases? Info requested

I am currently being tested for autoimmune diseases. I went to check-in virtually for my appointment with Dr. KK this week and saw a list of diagnoses.

Blood coagulation disorder

Female reproductive system disorder

Infertility due to azoospermia

Disorder of connective tissue

Selective immunoglobulin A deficiency

Hyperprolactinemia

Congenital uterine anomaly

Female infertility

Hashimoto thyroiditis

Polyclonal hypergammaglobulinemia

I knew about the azoo already- and at the testing I learned about some issues with my cervix and uterus which might go under 'congenital uterine anomaly'- and maybe my SERs in my eggs is listed under 'female reproductive disorder'? It's the highlighted ones I'm not really sure on. I am hoping to get my MRI results back soon for the hyperprolactinemia. Geesh- I can't even pronounce some of these.
If you know anything at all about the highlighted, please share. Thanks in advance 
***WARNING***

TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

   **ALL WELCOME**                                    My Blog 
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Re: What do you know about autoimmune diseases? Info requested

  • pblgepblge member
    edited February 2014
    Gosh, that is a lot to take in!!! It does seem possible that the same problem could result in multiple checks, especially for the vague ones like "female infertility." I don't have any knowledge to share, but I did want to send you big hugs. Perhaps with all this info in hand you'll finally be successful.

    (((Hugs)))
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
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  • IFinTN pretty muched summed it up... there are antibodies that are attacking your thyroid. It is usually genetic on your maternal line. It can be diagnosed through blood test and/or a sonogram of your thyroid.   Synthroid is the only thing prescribed and monitoring of your thyroid. It can make you feel pretty run down, gain weight, hair loss etc, cold/heat intolerance, etc.  People who have one auto-immune issue are more apt to have another one.  I have not been diagnosed with another one yet.   Not sure about the other ones! Good luck!
    ***siggy/ticker warning***

    Me:36 DH:38 TTC#1 since 4/2012
    Me DX: Hashimotos,Hypothyroid, DOR, MTHFR,  DH: normal

     IUI #1-#4 BFNs and a few cancelled cycles in the mix.
    - poor responder
    ***Suprise BFP on 6/13/13. Natural MC @6wks 3days
    IVF#1 and 2- Cancelled due to no response on max stimms
    FET 5/20- BFP
    1st Beta- 641
    2nd beta- 2166
    Sono- TWINS!!!!
    Two Boys! Born January 2015 @36 weeks.  Healthy and no NICU!  So blessed!



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  • Thanks for the replies.
    These are the disorders I came to the doctor with- not any of the ones she found. And its based on previous bloodwork prescribed by other doctors. I went to 2 rhuematologists and an endocrinologist because I know autoimmune runs in my family. They all said I was healthy. So it's just a little shocking that all of that is 'healthy'. 

    I knew based on the bloodwork that something had to be up. I am really hoping that you are right @IFinTN that these are all just signs of one thing, instead of multiple things. It may very well be lupus since I haven't been able to go out into the sun since 2007 due to horrible skin reactions.
    I go on Wednesday for my appoint. FX she doesn't find anything else.

    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
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