Infertility

Progress Report… Im feeling Bittersweet

jaztasticjaztastic member
edited February 2014 in Infertility

So I had my ER on Tuesday 2/11…

40 Follies Retrieved

31 Mature

25 Fertilized

 

Fast Forward to Day 5… 15 remaining blasts were biopsied and frozen.  I’m feeling bittersweet. I know 15 frosties is amazing!! I shouldn’t be complaining or upset at all… However when you have PGD testing done, that number can go down so quickly… I am not at the place where I want to risk transferring blasts that come back with genetic miscues in the hopes that everything works itself out. So now Im on pins and needles…I really want enough good ones to have 3 solid FET attempts.  Its no longer in my hands so Im trying hard to let go and relax.

In other news, I woke up this morning with some spotting which tells me AF is ON THE WAY!! Im so happy, because the sooner I can call CD1, the sooner I can get started with my FET cycle. 

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Waited a long time, tried a lot of stuff, science made me a mom.
 Loss and IF veteran. Current mom of DS 5.5, DD 2, and sometimes DH 40. Due June 2021 with TWINS

Re: Progress Report… Im feeling Bittersweet

  • 15 frosties sounds like a dream to me! Even after the PGD screens some out, the odds should leave you with enough for a few FETs :)
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • @RunCC37 You are right... I think about people like you and know I should feel much better but I just got that feeling in the pit of my stomach you know. My first fresh cycle I lost about 40% of my embies after PGD. So Im a little freaked out. But I cant do anything but take one day at a time. 
    *~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~
    Waited a long time, tried a lot of stuff, science made me a mom.
     Loss and IF veteran. Current mom of DS 5.5, DD 2, and sometimes DH 40. Due June 2021 with TWINS
  • Loading the player...
  • 15 is exciting! Congrats!
    Me: 30 DH: 30 ~ TTC #1 Since August 2011 
    BFP #1 2/28/13, Ectopic, Tubal surgery 3/25 
    Began RE testing 8/8, Dx Unexplained, 
    IUI #1 11/1=BFN Moving on to IVF 
    IVF #1 12/2 ER 8R 7M 4 fertilized
    12/7 Transferred 2 "perfect" little blasts 12/17 BFN
    New DX= DOR, I fu*kng hate IF
    1/14 Hysteroscopy, new clean uterus!
    IVF #2: bcp, Lupron, follistim 300, menopur 225. 2/21 8R 4M 3F. 3dt of 2 perfect embryos. 1 little penguin 
     3/10 BFFN
    Regrouping. Seeing reproductive immunologist Dr. Kwak Kim 6/10 
    Kwak Kim protocol: Metformin 1000mg, vitamin D 4000iu, vitamin E 400iu, baby aspirin, Metanx, levothyroxine 75mcgs 
     Surprise BFP 9/21!!! Beta #1 247, Beta #2 630. Miscarried 10/13

  • 40% of 15 is 6 which leaves you with 9 :) That sounds awesome to me! Don't you wish we could just fast forward a few days to get the results?! I have found the few days waiting for fert reports to be far worse than any 2ww I've ever gone through. When do you get your results?
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • 15 frosties is a great number, even if you loose 40% after PGD, that would still leave you with 9 frosties, which is still amazing. 

    I know it's hard not to stress and worry, but try not to.  Your cycle is looking amazing right now, try to relax and enjoy the good news.

    imageimageimageimageimage

     

    image

    TTC #1 since August 2011

    My Blog

    September 2012: Start IF testing

    DH (32): SA is ok, slightly low morph, normal SCSA  Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA

    October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos

    November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues.  Converted to freeze all due to lining issues.  2 blasts frozen on day 6!

    January 2015: FET #2 Cancelled due to lining issues

    April 2015: FET #2.1


    PAIF/SAIF Welcome!

  • @RunCC37 Im laughing at myself because I probably sound like such a spaz cat right now. "OHHH THE WORLD IS ENDING" at least that what it feels like in my head. I swear these IF drills take bits of our insanity day by day. I should get results back by Thursday.
    *~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~
    Waited a long time, tried a lot of stuff, science made me a mom.
     Loss and IF veteran. Current mom of DS 5.5, DD 2, and sometimes DH 40. Due June 2021 with TWINS
  • We are all spaztastic going through this! Hang in there! I hope the time zips by between now & Thursday :)
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • I think many people would be happy to have nine retrieved, let alone nine frosties. I see nothing to freak about, although I understand we all freak in this process.
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
  • 15 is a good number to work with. Many people would die for that many.  Its great you can do PGD bc you have so many. Hoping they come back healthy.  
    ***SIGGY WARNING***

    DX: Unexplained
    6 Failed IUIs (Clomid and Gonal F).  
    IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
    Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
    12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
    After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
    2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
    BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


    All Welcome
  • DH has Translocation so PGD is pretty much mandatory. RE strongly advises against us doing a transfer without it (damn near refuses to let us do it). I know 15 is a lot... but when you have to push your body so hard to get high numbers to start out with its devastating watching them dwindle down so fast. My first IVF at ER I had 53 Follies... and ended up with 0 babies. So paranoia set in after my day 5 update call. 
    *~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~
    Waited a long time, tried a lot of stuff, science made me a mom.
     Loss and IF veteran. Current mom of DS 5.5, DD 2, and sometimes DH 40. Due June 2021 with TWINS
  • that is awesome, good luck!
  • HopefulSoul2HopefulSoul2 member
    edited February 2014
    @jaztaz1 - I can imagine how stressful it must be worrying about your little embies dwindling down.  Our worry never seems to end.  Try to stay positive - we are all rooting for you! Fingers crossed tight :)

    f/k/a/ Kari3629

    Me: 40/DH: 34

    Unexplained IF

    IVF #1 - 9/2013 8ER/5M/4EF/4ET = BFN

    IVF #2 - 2/2014 - Fingers crossed this is the one!

    4ER/3EF/3 "beautiful embryos" transferred - Beta March 7 = BFN :(

    Everyone Welcome!

    Image and video hosting by TinyPicimageimage

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  • FX for you!!  15 sounds like a great number to me!

    Me (36) - LOR, DH (34) - MFI (low count & poor motility)

    TTC since 01/2012

    11/2012-04/2013 Unmonitored Clomid cycles through OB/GYN; Referred to RE

    05/2013-Benched due to cyst

    06/2013 - Clomid 50 mg + HCG Trigger + TI = BFN

    07/2013 - Clomid 50 mg + HCG Trigger + IUI #1 = BFN

     08/2013 - Clomid 50 mg + HCG Trigger + IUI #2 = BFN

    09/2013 - Benched for lap & hysteroscopy (Stage II Endo Removed)

    10/2013 - Menopur + HCG Trigger + IUI #3 = BFN

    11/2013 - Menopur + HCG Trigger + IUI #4 = BFN

     12/2013 - Clomid + HCG Trigger + IUI #5 = BFN

    2/2014 - IVF #1 - Microdose Lupron Flare Protocol - 5R/4M/4F w/ICSI; 2 embies transferred on day 3 (none to freeze)

    2/27/14 - First BFP Ever!!!  EDD 11/3/14

     

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  • Good luck!!!


     

     All Welcome :)

    imageimage

    ***Losses mentioned***

    ***TTC since June 2011
    ***DH to see urologist Feb. 2013
    ***BFP #1: Feb. 2nd, 2013; M/C #1: Feb. 12th, 2013 5w3d :'(
    ***1st RE appt. April 10th, 2013
    ***IUIs #1-4 all failed
    ***IVF Consult October 7th, 2013
    ***IVF #1- January 2014: ER 1/20, ET of 2 embryos 1/23, Beta 2/5 *none to freeze*

    ***Feb 14th, 2014- M/C #2 @ 5w5d :'(

    ***RPL Bloodwork---- diagnosed with Factor V Leiden and MTHFR

    ***appt. w/ Genetic Counselor- April 18th

    ***hysteroscopy/laparoscopy scheduled for May 22nd- looks good

    ***IVF #2- July 2014

    ***7/26 Retrieval- 3 eggs :( , 2 fertilized :), none to freeze

    ***7/28 ET- 2dt of 2 embryos, stick little embies!!!

    ***8/11 beta- BFN :(

    ***WTF- DE IVF best option now

    ***DE IVF- January 2015

    image

    imageimage

    imageimage

    imageMissing my 5 angels

  • I just sent 9 for testing and I'm ESTATIC! lol But I know translocation is a whole different ballgame. Since we doing CGH testing my RE will only allow me to transfer 1. If you end up with 40% back that's 9 transfers!! Holy cow!
    Me (28) DH (32)  Endometriosis                                                                                   IVF  #1 (1/2013) - 17 Retrieved, 16 Mature, 14 Fertilized- 2 transferred- BFN
    FET #1 (7/2013) - 2 embryos - BFN
    FET #2 (9/2013) - 2 emrbyos - BFN
    New RE. Fresh Start
    IVF  #2 (2/2014) - 25 Retrieved, 19 Mature, 16 Fertilized, 9 blasts.
                                 CGH Testing: 6 Normal
    FET #3 (4/2014) -1 embryo -  BFP! Beta#1: 35 Beta #2: 16 :(
    FET #4 (5/2014) -1 embryo -  BFP! Beta#1: 321!!! Beta #2: 727.9!
    6/5/2014 Heartbeat! 144bpm It's a girl!
    Due January!
     
     

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