Infertility

Intro- loss and Ivf failure mentioned

I am having a really hard time dealing with my emotions and I'm also looking for advice. I posted on secondary IF and someone told me that I might be more comfortable here since I don't have a child. A little about me. My name is Nicole and I'm 29. My husband and I have been together for 9 years, married for 2 1/2. After a little over a year of trying, we got pregnant via unmedicated iui. -- the first time! Unfortunately it was a blighted ovum. I carried until I was 10 weeks and then had a d&c. The loss was so terrible. You start to believe in miracles and then your heart gets broken. Well, fast forward 8 months, 6 more iuis and still not even a hint of a bfp. This month we turned to Ivf. After being so scared to see how my eggs were, my fsh is high for my age (9-10.1 range). I had 30 follicles at my baseline apt. Well, my dr had me trigger after 7 days of stimming. I believe because my estrogen was high (3300). At retrieval I was shocked to get 22 eggs. I woke up ANC my husband was smiling away. Well, only 8 of those eggs were mature. All 8 fertilized and on the day if the 3dt, I had 4 @ 8a and the others were 8b, 6a and 2@5a. We transferred an 8a that was compacting. Well it was a BFN. now I'm lost, scared and have this fear that there's something wrong with me. Is this normal? We're pushing to do a FET this cycle with 2 day 3 embryos since we were Able to freeze all 7. Any advice or input would be greatly appreciated

******Siggy Warning**************

Me 29 - no known issues ( Highest FSH 10.1??) 
DH- 36 - quite the perfect man!
TTC since 1/2011
IUI #1 March 2012 
BETA #1  BFP
B/O at 6 weeks D&C @ 10 weeks 
IUI #2-7 (2012)= BFN
IVF  Jan 14 - Follistim, Ganirelix
22R, 8M, 8F
ET  (1-14-14) - 1 Grade A 8 cell = BFN
FET (2-18-14)  1 grade A 12 cell and one early morula!
BETA #1 (3-3-14) =1,389  p4 17.4
BETA #2  (3-5-14) = 4,553 u/s showed one small g sac
U/S #2      (3-17-14) Shows two little beans with heartbeats!!! TWINS!! 
                                   Heartbeats were 119 & 120 beans measured (6 weeks 1 day) (6 weeks 2 days)
found out at 20 weeks that baby B went to heaven
11/12/14 Baby girl arrived :)
FET (1-24-16) Grade A early morula 
BETA #1 300 p4. 11.1 
BETA#2 1300
u/s d 1 tiny babe :)
10/7/16 another sweet baby girl
4/18 SURPRISE + HPT 
Beta #1 6 weeks 16,202 p4. 13.2




Re: Intro- loss and Ivf failure mentioned

  • Welcome to the board. It's not a happy place to have to be, but there are lots of supportive women here with experiences similar to yours. It's a rough journey, but I have definitely found that these boards help. If you're going to be doing a FET in February, you could join the Hopeful Hearts group to go through the process with others.

    Best of luck for your upcoming cycle! *hugs*
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
  • Welcome. I'm sorry you're going through this. We have also had a failed IVF and are now on #2.
    I know it's so hard to process a failed IVF that seems so perfect. Good luck with your FET next month!
    Me: 30 DH: 30 ~ TTC #1 Since August 2011 
    BFP #1 2/28/13, Ectopic, Tubal surgery 3/25 
    Began RE testing 8/8, Dx Unexplained, 
    IUI #1 11/1=BFN Moving on to IVF 
    IVF #1 12/2 ER 8R 7M 4 fertilized
    12/7 Transferred 2 "perfect" little blasts 12/17 BFN
    New DX= DOR, I fu*kng hate IF
    1/14 Hysteroscopy, new clean uterus!
    IVF #2: bcp, Lupron, follistim 300, menopur 225. 2/21 8R 4M 3F. 3dt of 2 perfect embryos. 1 little penguin 
     3/10 BFFN
    Regrouping. Seeing reproductive immunologist Dr. Kwak Kim 6/10 
    Kwak Kim protocol: Metformin 1000mg, vitamin D 4000iu, vitamin E 400iu, baby aspirin, Metanx, levothyroxine 75mcgs 
     Surprise BFP 9/21!!! Beta #1 247, Beta #2 630. Miscarried 10/13

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  • Thank you both so much for replying and for the advice.
    Missmarypoppins, thank
    You and that was my drs exact wording "everything went perfect". I'm sorry to hear about your IVF. two of my best friends got pregnant in the last year from their first IVF and we all used the same dr. I knew it would be to good to be true. Are you in the middle of your IVF?

    ******Siggy Warning**************

    Me 29 - no known issues ( Highest FSH 10.1??) 
    DH- 36 - quite the perfect man!
    TTC since 1/2011
    IUI #1 March 2012 
    BETA #1  BFP
    B/O at 6 weeks D&C @ 10 weeks 
    IUI #2-7 (2012)= BFN
    IVF  Jan 14 - Follistim, Ganirelix
    22R, 8M, 8F
    ET  (1-14-14) - 1 Grade A 8 cell = BFN
    FET (2-18-14)  1 grade A 12 cell and one early morula!
    BETA #1 (3-3-14) =1,389  p4 17.4
    BETA #2  (3-5-14) = 4,553 u/s showed one small g sac
    U/S #2      (3-17-14) Shows two little beans with heartbeats!!! TWINS!! 
                                       Heartbeats were 119 & 120 beans measured (6 weeks 1 day) (6 weeks 2 days)
    found out at 20 weeks that baby B went to heaven
    11/12/14 Baby girl arrived :)
    FET (1-24-16) Grade A early morula 
    BETA #1 300 p4. 11.1 
    BETA#2 1300
    u/s d 1 tiny babe :)
    10/7/16 another sweet baby girl
    4/18 SURPRISE + HPT 
    Beta #1 6 weeks 16,202 p4. 13.2




  • I been there. After my first failed IVF I was so upset. Nothing you can do but keep on trying. Its great you have so many frozen.  I hope you have success with a FET.  
    ***SIGGY WARNING***

    DX: Unexplained
    6 Failed IUIs (Clomid and Gonal F).  
    IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
    Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
    12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
    After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
    2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
    BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


    All Welcome
  • Thank you all. It is terribly hard as some of you know and start to wonder if it's even possible. Sometimes I am okay and others my heart just aches.

    ******Siggy Warning**************

    Me 29 - no known issues ( Highest FSH 10.1??) 
    DH- 36 - quite the perfect man!
    TTC since 1/2011
    IUI #1 March 2012 
    BETA #1  BFP
    B/O at 6 weeks D&C @ 10 weeks 
    IUI #2-7 (2012)= BFN
    IVF  Jan 14 - Follistim, Ganirelix
    22R, 8M, 8F
    ET  (1-14-14) - 1 Grade A 8 cell = BFN
    FET (2-18-14)  1 grade A 12 cell and one early morula!
    BETA #1 (3-3-14) =1,389  p4 17.4
    BETA #2  (3-5-14) = 4,553 u/s showed one small g sac
    U/S #2      (3-17-14) Shows two little beans with heartbeats!!! TWINS!! 
                                       Heartbeats were 119 & 120 beans measured (6 weeks 1 day) (6 weeks 2 days)
    found out at 20 weeks that baby B went to heaven
    11/12/14 Baby girl arrived :)
    FET (1-24-16) Grade A early morula 
    BETA #1 300 p4. 11.1 
    BETA#2 1300
    u/s d 1 tiny babe :)
    10/7/16 another sweet baby girl
    4/18 SURPRISE + HPT 
    Beta #1 6 weeks 16,202 p4. 13.2




  • Im sorry you are dealing with a failed cycle, and very sorry for your loss. This board is amazing- I hope that your FET is a success and your stay here is short. In the meantime, welcome to the board <3
    Image and video hosting by TinyPic
    Anniversary

    TTC since 2008
    Dh:34, no issues.  Me:31, Endo, slightly hypothyroid, deformed ovary, paracentric inversion.
    4 Gonal-F, Cetrotide, HcG, Crinone +TI cycles= all BFN
    Lap in 2012 to remove large unresolving cyst discovered endo and double lobed ovary.
     6 Gonal-F, Cetrotide, HcG, Crinone IUI cycles= All BFN,
    1st IVF w/ICSI- June '13 Antagonist: Gonal-F, Menopur, Ganirelix, HcG, Estradiol, Crinone= 7 retrieved, 4 mature, 1 unfertilized, 2 abnormally fertilized, 1 normally fertilized.  2DT of only embryo and our miracle BFP.
    Our beloved baby boy was born sleeping Oct. 13, 2013 due to pROM/IC/Uterine infection.
    2nd IVF w/ICSI- Feb. '14 EPP/lupron/antagonist: Estrace, lupron, HGH, Gonal-F, Menopur, HcG, PIO, lovenox, doxy/dex.=21 retrieved, 16 mature, 15 fertilized!!  5dt of 1 blast/ 6 frozen. BFP!  Beta 1 9dp5dt:83.9  Beta 2: 11dp5dt: 145.2  Beta 3  14dp5dt: 497  Please be our sticky rainbow baby!

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    Lilypie Angel and Memorial tickers


    imageimage
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