Antagonist IVF cycles?

pblge

I'm an over-responder, meaning that when given small amounts of injectable drugs I produce dozens of follies. Unfortunately, I'm also "brittle," which means that I usually crash before the follies get big enough for whatever procedure I'm supposed to do. I've had cancelled cycles because of this, and IVF #1 (long lupron proptocol) was nearly cancelled too. My doctor has recommended that I try the antagonist cycle next. I'm confused by this, because everything I've read suggests that these are used for poor responders, which I definitely am not. Does anyone understand why my RE would suggest this?

Thanks!

violetmarie61516

It's also used for better egg quality.  That's probably what your RE is going for.  Good luck!

FloridaSun82

I did an antagonist cycle and I think my doctor expected me to be an over-responder. I think it's so you can stay on a low dose for an extended period of time (low and slow, as my RE says) and not worry about your body trying to ovulate or move too fast. I stimmed for 15 days on an antagonist cycle, but they kept my meds low and a strict eye on my estrogen so they would not get an over-response. Also, when you do this, you can use a Lupron trigger (obvi you can't trigger with Lupron if you're using it) and the Lupron practically eliminates the risk of OHSS, although you need to supplement with a lot of luteal phase support.

Keephope2012

*siggy warning* 

My RE had me on an antagonist protocol with my first round of IVF given my over response to clomid (3-4 follies on 25 mg). He did mention the benefit of possibly being able to use a Lupron trigger. I believe he also said it was one of their standard first IVF protocols at my clinic with no other known issues like DOR or AMA. Good luck!

AquaJacks

I did an antagonist protocol with Lupron trigger. I ended up with 21 to freeze and am currently waiting for my FET. I did a freeze all due to the high response. All the best!