Tonight was my first PIO injection and I was pretty scared. When we first started IVF way back when my DH had to coax me for an hour before he gave me my subcutaneous shots. So that gives you an idea of my fear level. Anyway I did really well staying calm and iced before hand. When it came time I didn't feel a thing except a small poke. It was so small that I had to ask DH if it was in! (He lied and said no... LOL)
My question is, does it get worse over time? Because this really was nothing at all. He massaged for a few minutes after with a warm facecloth and I've been sitting on a heating pad for a half an hour now.
TTC since 4/12
Me: 32, All clear, DH: 34, low count
IVF /ICSI: 4/18/13~ OHSS~Freeze-all
FET #1 6/28/13 BFN
FET #2 7/29/13 BFN
FET #3 12/16/13 BFN
*NEW RE*
IVF/ICSI #2 3/18/14 BFP, twins m/c 9w4d
IVF/ICSI #3 08/25/14 BFN
FET #4 10/14 BFN
IVF/ICSI #4 1/23/14 BFP Twins!
Re: PIO graduates
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
DX: Unexplained
BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121. US at 8w3d measuring on track HR 177. Released form my RE. EDD 12/28
@babydreams13 I would like a full report on your PIO experience too!
ET 9/10 - transferred 1 perfect 5AA blast
7dp5dt BFP ~~ Beta on 9/19 - 77.4 Beta #2 on 9/21 - 357
Low heartbeat on 10/7 86, lower heartbeat on 10/11 76, no heartbeat 10/14/13. D&C 10/15/13
Tests revealed MTHFR c677t mutation, put on Folgard.
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FET #1 1/6/14 - 4BB blast - BFN
Married September 17, 2011.
Me 38, PCOS
H 43, SA normal.
TTC #1 since November 2011.
HSG - both tubes clear.
Metformin+ Clomid + Prometrium (Ob/Gyn)
January 2012- Chemical Pregnancy
June 2012- BFP- Ectopic (5 weeks), Methotrexate
November 2012- BFP- Miscarriage (5 weeks),D&C(12/14/12)
December 17, 2012 first apt with RE
Metformin + Folgard+ Clomid+ Bravelle + TI +Prometrium (RE)
March 2013- 2 follicles- BFN
April 2013- 2 follicles- BFN
Oct 2013, IVF #1- fresh cycle cancelled due to increased progesterone
ER 11/7/2013- 20 retrieved, 19 mature, 14 fertilized naturally, 3 blasts frozen
FET #1- 12/6/13, 2 blasts xfered- BFN
FET #2- Cancelled while sitting in the waiting room... blast didn't survive thaw
I did them for IVF#1 and was scared too. They are not bad. I didn't ice...just massaged afterwards and then kept moving....i.e. walking, doing laundry, etc. My husband was more nervous to have to give them to me, but remember to put your weight on the leg NOT getting the shot in. It allows the muscle to be relaxed. You'll do great and in a week will be like "what was the big deal?"
************** Siggy Warning************
Married August 2012 -- Me (40 yrs old) My husband (45 yrs. old)
RE referral from ObGYN in late Jan. 2013 -- Testing Confirms Unexplained IF
IUI #"s1 - 3 (Femara + IUI) April - June 2013 - all BFN
Decided to do IVF... Began stimming on September 10th! Egg Retrieval 9/20/13. 19 eggs: 6 to mature to freeze after 6 fertilized with ICSI
3 morula stage embryos transferred on 9/25/13.....Beta #1 on 10/4/13/ = 7.5 Beta #2 on 10/6/13 = negative
IVF#2 - Lupron plan (set to begin on 10/28/13) (Planning on thawing and fertilizing our 6 eggs with ICSI as well as all of the mature eggs they retrieve with this fresh cycle.)
Late October 2013 - ectopic pregnancy - methotrexate injection....benched 3 months
CD1 - 12/5/13...Lupron set to start on 12/26/13; CD1 - 1/2/14....Baseline 1/3/14....begin follistim tonight and continue with lupron. (Got my calendar today! IVF#2 is a go!)
ER = 1/14/14 (11 eggs....9 were mature. 9 fertilized. Of the 6 mature eggs we thawed, only 4 fertilized. At this time, we have 13 eggs fertilized and growing. Waiting for news about a 3-day or 5-day transfer.)
ET = 1/19/14 (5dt).....3 blastocysts transferred! (All nine embryos didn't make it to freeze. =( )
Beta #1 = 1/28/14 (2 weeks after ER) BFP! 209 (9dp5dt) EDD 10/7/14
Beta #2 - 1/30/14 (11 dp5dt) 302
Beta #3 - 2/3/14 (15 dp5dt) 1222
Ultrasound set for 2/17/14......TWINS! Twin A - HR 124 bpm; Twin B - HR 126 bpm
Final Ultrasound with RE 3/10/14 - Twin A - HR 176 bpm; Twin B - HR 177 bpm.
PAIF/SAIF Welcome!
DX: Unexplained
BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121. US at 8w3d measuring on track HR 177. Released form my RE. EDD 12/28
Good discussion going on here about PIO. The first week or so wasn't bad at all for me, I iced and massaged after. No lumps or pain really. However, I am really starting to get quite sore and even having some pain (just in general, not from the shot itself). I think that's because I haven't been using heat. Guess I thought since it started out okay, I didn't really need it, but boy am I going to need to start!
However, I'm in my 2ww and wanted to double check that a heating pad would be okay to use during this time period after the transfer..........
**** Ticker Warning ****
Me: 37, DH: 38 Married since 2005, TTC since 2007
IVF#1 February 2013 - 6R, 4M, 3F - transferred 2 day 3; 1 frozen - BFN
IVF#2 May 2013 - Menopur, Follistim, Ganirilex - 16R, 13M - freeze all eggs due to MFI 0% Motility day of retreival
FET September 2013 - 9 eggs thawed, 0 fertilized transferred frostie from IVF #1 - Estrace & PIO - BFN
**Change RE**
January 2014 - IVF #3 (Lucky #3?!) ER 2/5/14 19R, 16M, 11F with PICSI.
2/10/14 Transferred 2 AA day 5 blasts , 5 Frozen - Estrace & Endometrim (which IMO is worse than PIO!!)
Beta 2/24/14 Beta #1: 2229, Beta #2: 3577 BFP!!
6 week u/s - TWO heartbeats
EDD 10/30/14
***** All Welcome *******
Yes, a heating pad is okay to use, my nurse said that if you are icing then you should sit on heat for a little bit afterwards. I noticed that the longer I sit on it the better. So usually I heat for 30 minutes or more, on the couch watching tv/reading.
Obsessive Charting & OPK'ing
Clomid 3/2011: BFN
HSG: Normal
Dx: DOR (at 29... currently 31)
IVF #1 7/2011 On BCP & Lupron 10iu 8/6: Stim Start (Menopur & Gonal F
Day 14 of stims: One 19.9 and one 20 follicle Estro: 908.
ER 8/21/11. 4 Eggs... only 2 were mature enough. ET: 8/24 ICSI
9/6 Beta: 9.2 (low positive) 9/7 HPT: BFN
9/8/11 ANOTHER Beta: BFN
TTC Naturally
3/2012 Lap done, very little endo. What now?
12/30/13 Beta- Hcg in the negatives. BFN
TTC Naturally again...